L-苹果酸

53篇引用文献

COA

级别和纯度:

用于细胞培养

适用于昆虫细胞培养

CAS编号: 97-67-6
分子式: C₄H₆O₅
分子量: 134.09
Beilstein号: 1723540
EC号: 202-601-5
MDL号: MFCD00064213
PubChem编号: 222656
PubChem SID: 504757916

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货号 (SKU)	包装规格	是否现货
M119455-25g	25g	现货
M119455-100g	100g	现货
M119455-500g	500g	现货

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代谢物 (8911) 手性拆分剂 (8) 手性砌块 (39) 手性非杂环砌块 (288) 羧酸 (2181)

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基本描述

别名	L-羟基丁二酸 \| L-(-)-苹果酸 \| L-(-)-羟基丁二酸 \| (S)-(-)-2-羟基琥珀酸
英文别名	Apple acid \| L-2-Hydroxybutanedioic acid \| malic-acid \| L-Maleic Acid \| L-MALIC ACID [WHO-DD] \| M0022 \| STK048584 \| (S)-Hydroxybutanedioic acid \| (S)-hydroxy-Butanedioic acid \| 3-08-00-03357 (Beilstein Handbook Reference) \| 4elc \| L-(-)-Malic acid, BioXtr
规格或纯度	用于细胞培养, 用于昆虫细胞培养
英文名称	L-(-)-Malic acid
生化机理	苹果酸是细胞代谢的一部分。它可应用于制药领域中。它可有效治疗肝功能不全、对抗高氨血症。它可用作氨基酸输注的一部分。苹果酸还可以作为纳米药物治疗脑神经系统疾病。一种TCA（Krebs循环）中间体以及苹果酸天门冬氨酸穿梭的分子伴侣。
应用	γ-氨基丁酸合成酶抑制剂。
储存温度	避光,充氩,干燥
运输条件	常规运输
产品介绍	苹果酸可用作昆虫组织培养的成分。它也可用作软饮料、果酱、水果和蔬菜汁中的酸化剂。产品用途苹果酸已被用于：在线粒体细胞培养中诱导基础呼吸；测定线粒体ETC（电子传输链）活性；作为线粒体底物成分的一种。 Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices. Product Application Malic acid has been used: to induce basal respiration in mitochondrial cell culture. to measure the mitochondrial ETC (electron transport chain) activity. as a component of mitochondrial substrate stock.

关联靶点（其它种属）

A085R Prolyl 4-hydroxylase (72 活性数据)

点击查看靶蛋白信息： A085R

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504757916
EC号	202-601-5
分子类型	小分子
IIUPAC Name	(2S)-2-hydroxybutanedioic acid
INCHI	1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChi Key	BJEPYKJPYRNKOW-REOHCLBHSA-N
Smiles	C(C(C(=O)O)O)C(=O)O
Isomeric SMILES	C([C@@H](C(=O)O)O)C(=O)O
分子量	134.09
Beilstein号	1723540
Reaxy-Rn	1723539
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723539&ln=

化学和物理性质

溶解性	water: 100 mg/mL, clear to slightly hazy, colorless
密度	1.7197
敏感性	对湿度敏感;对空气敏感
比旋光度	-6.5° (C=10,Acetone)
闪点(℃)	220°C
熔点	101-103°C
分子量	134.090 g/mol
XLogP3	-1.300
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	5
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	134.022 Da
单同位素质量Monoisotopic Mass	134.022 Da
拓扑极表面积Topological Polar Surface Area	94.800 Å²
重原子数Heavy Atom Count	9
形式电荷Formal Charge	0
复杂度Complexity	129.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany	3
Merck Index	5707
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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批号(Lot Number)	证书类型	货号
A2215437	分析证书	M119455
A2215438	分析证书	M119455
A2215536	分析证书	M119455
I2107497	分析证书	M119455
G2110010	分析证书	M119455
A2424102	分析证书	M119455
I2525020	分析证书	M119455
A2424098	分析证书	M119455
A2424101	分析证书	M119455
A2424202	分析证书	M119455
K1520164	分析证书	M119455
F2213127	分析证书	M119455
F2213128	分析证书	M119455
F2217222	分析证书	M119455
F2217223	分析证书	M119455

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引用文献

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溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度