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1-甲基-D-色氨酸, mTORC1 激活剂

吲哚胺2,3-二加氧酶（IDO）抑制剂
6篇引用文献 COA COA
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货号 (SKU) 包装规格 是否现货 价格 数量
M115830-250mg
 250mg 现货 Stock Image
M115830-1g
 1g 现货 Stock Image
M115830-5g
 5g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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Amino Acid/Protein Metabolism (4559) Indoleamine 2,3-Dioxygenase (IDO) (21) Metabolic Enzyme/Protease (4889)
main product photo

基本描述

英文别名 AKOS015850753 | Indoximod (NLG-8189) | AKOS015898463 | D-1-methyltryptophan | NCGC00346842-01 | NSC721782 | NSC-721782 | SMP2_000028 | A14397 | CCG-266709 | D10640 | AMY22762 | D-Trp(Me)-OH | Indoximod (USAN/INN) | ZADWXFSZEAPBJS-SNVBAGLBSA-N | A822528 |
规格或纯度 Moligand™, ≥96%
英文名称 1-Methyl-D-tryptophan
生化机理 甲基化色氨酸，可作为吲哚胺2,3-二加氧酶（IDO）抑制剂。防止小鼠过度表达IDO的树突状细胞触发的T细胞无反应。
运输条件 常规运输
作用类型 激活剂
作用机制 mTORC1 激活剂
产品介绍

用于制备天然产物如大灵生物碱（macroline alkaloids）；也用在色氨酸酯类和醛类的Pictet-Spengler反应；也用于合成1位取代的indolactam前体。
纯度 ≥96%

产品属性

ALogP -1.3

关联靶点（人）

A498 (42825 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHN (49357 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CAKI-1 (44928 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
COLO 205 (50209 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
K562 (73714 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KM12 (47707 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
M14 (47487 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MOLT-4 (49676 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OVCAR-3 (48710 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OVCAR-4 (44535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OVCAR-5 (45555 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OVCAR-8 (47708 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PC-3 (62116 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RPMI-8226 (44974 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RXF 393 (41971 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SF-295 (48000 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SK-MEL-2 (46422 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SK-MEL-28 (48833 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SK-OV-3 (52876 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SN12C (47755 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SNB-19 (46794 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TK-10 (45540 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
U-251 (51189 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UACC-257 (46019 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UACC-62 (47335 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UO-31 (46270 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
786-0 (47912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NCI/ADR-RES (33767 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
T47D (39041 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EKVX (44102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NCI-H322M (45589 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HCC 2998 (41480 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HCT-116 (91556 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NCI-H460 (60772 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SF-268 (49410 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HUVEC (11049 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
IGROV-1 (47897 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
LOX IMVI (44321 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HOP-62 (47048 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-435 (38290 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-N (28205 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Malme-3M (44254 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ido2 Indoleamine 2,3-dioxygenase 2 (105 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488189681
分子类型 小分子
IIUPAC Name (2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid
INCHI 1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
InChi Key ZADWXFSZEAPBJS-SNVBAGLBSA-N
Smiles CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N
Isomeric SMILES CN1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)N
分子量 218.25
Reaxy-Rn 20071
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20071&ln=

化学和物理性质

密度 1.28
熔点 242-245°C
分子量 218.250 g/mol
XLogP3 -1.300
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 218.106 Da
单同位素质量Monoisotopic Mass 218.106 Da
拓扑极表面积Topological Polar Surface Area 68.300 Ų
重原子数Heavy Atom Count 16
形式电荷Formal Charge 0
复杂度Complexity 270.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 3

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到8个结果

批号(Lot Number) 证书类型 货号
I2526058 分析证书 M115830
G2028027 分析证书 M115830
G2028026 分析证书 M115830
C1922017 分析证书 M115830
H2508809 分析证书 M115830
E2227449 分析证书 M115830
E2227451 分析证书 M115830
E2227463 分析证书 M115830

此产品的引用文献

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引用文献

1. Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC.  (2007)  Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan..  Cancer Res,  67  (15): (7082-7).  [PMID:17671174]
2. Ball HJ, Yuasa HJ, Austin CJ, Weiser S, Hunt NH.  (2009)  Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway..  Int J Biochem Cell Biol,  41  (3): (467-71).  [PMID:18282734]
3. Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, Sutherland CL.  (2011)  Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors..  Biochim Biophys Acta,  1814  (12): (1947-54).  [PMID:21835273]
4. Fatokun AA, Hunt NH, Ball HJ.  (2013)  Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease..  Amino Acids,  45  (6): (1319-29).  [PMID:24105077]
5. Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LM, Pigott E, Keough MP, Rust S, Mellor AL et al..  (2014)  IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation..  Int Immunol,  26  (7): (357-67).  [PMID:24402311]
6. Charlotte A Williams,Rachel A Harry,Julie D McLeod.  (2007-12-11)  Apoptotic cells induce dendritic cell-mediated suppression via interferon-gamma-induced IDO..  Immunology,  124  ((1)): (89-101).  [PMID:18067553]
7. Adriano Boasso,Andrew W Hardy,Stephanie A Anderson,Matthew J Dolan,Gene M Shearer.  (2008-08-14)  HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation..  PloS one,  3  ((8)): (e2961-e2961).  [PMID:18698365]
8. Ute F Röhrig,Loay Awad,Aurélien Grosdidier,Pierre Larrieu,Vincent Stroobant,Didier Colau,Vincenzo Cerundolo,Andrew J G Simpson,Pierre Vogel,Benoît J Van den Eynde,Vincent Zoete,Olivier Michielin.  (2010-01-09)  Rational design of indoleamine 2,3-dioxygenase inhibitors..  Journal of medicinal chemistry,  53  ((3)): (1172-1189).  [PMID:20055453]
9. Carla M Cuda,Alexander V Misharin,Angelica K Gierut,Rana Saber,G Kenneth Haines,Jack Hutcheson,Stephen M Hedrick,Chandra Mohan,G Scott Budinger,Christian Stehlik,Harris Perlman.  (2014-05-09)  Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation..  Journal of immunology (Baltimore, Md. : 1950),  192  ((12)): (5548-5560).  [PMID:24808358]
10. Yuko Tanizaki,Aya Kobayashi,Saori Toujima,Michihisa Shiro,Mika Mizoguchi,Yasushi Mabuchi,Shigetaka Yagi,Sawako Minami,Osamu Takikawa,Kazuhiko Ino.  (2014-05-16)  Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment..  Cancer science,  105  ((8)): (966-973).  [PMID:24826982]
11. Hiroyasu Ito,Tatsuya Ando,Yuko Arioka,Kuniaki Saito,Mitsuru Seishima.  (2014-10-18)  Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model..  Immunology,  144  ((4)): (621-630).  [PMID:25322876]
12. Soranobu Ninomiya,Neeharika Narala,Leslie Huye,Shigeki Yagyu,Barbara Savoldo,Gianpietro Dotti,Helen E Heslop,Malcolm K Brenner,Cliona M Rooney,Carlos A Ramos.  (2015-05-06)  Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs..  Blood,  125  ((25)): (3905-3916).  [PMID:25940712]
13. Adrian M Seifert,Shan Zeng,Jennifer Q Zhang,Teresa S Kim,Noah A Cohen,Michael J Beckman,Benjamin D Medina,Joanna H Maltbaek,Jennifer K Loo,Megan H Crawley,Ferdinand Rossi,Peter Besmer,Cristina R Antonescu,Ronald P DeMatteo.  (2016-07-30)  PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors..  Clinical cancer research : an official journal of the American Association for Cancer Research,  23  ((2)): (454-465).  [PMID:27470968]
14. Cara C Schafer,Yong Wang,Kenneth P Hough,Anandi Sawant,Stefan C Grant,Victor J Thannickal,Jaroslaw Zmijewski,Selvarangan Ponnazhagan,Jessy S Deshane.  (2016-10-06)  Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment..  Oncotarget,  7  ((46)): (75407-75424).  [PMID:27705910]
15. Kyu Hwan Kwack,Jung Min Lee,Sang Hyuk Park,Hyeon Woo Lee.  (2016-11-23)  Human Dental Pulp Stem Cells Suppress Alloantigen-induced Immunity by Stimulating T Cells to Release Transforming Growth Factor Beta..  Journal of endodontics,  43  ((1)): (100-108).  [PMID:27871783]
16. M A G Rabbani,Sailen Barik.  (2017-01-24)  5-Hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus..  Virology,  503  (46-51).  [PMID:28113063]
17. Z Xie,M Zhang,W Xiong,H Y Wan,X C Zhao,T Xie,H Lei,Z C Lin,D S Luo,X L Liang,Y H Chen.  (2017-01-31)  Immunotolerant indoleamine-2,3-dioxygenase is increased in condyloma acuminata..  The British journal of dermatology,  177  ((3)): (809-817).  [PMID:28132413]
18. Tatsuya Sakamoto,Riho Onuma,Shoko Furukawa,Akane Hayasaka,Mayu Onozato,Hiromi Nakazawa,Hideaki Iizuka,Hideaki Ichiba,Takeshi Fukushima.  (2017-10-20)  Liquid chromatography-mass spectrometry with triazole-bonded stationary phase for N-methyl-D-aspartate receptor-related amino acids: development and application in microdialysis studies..  Analytical and bioanalytical chemistry,  409  ((30)): (7201-7210).  [PMID:29046924]
19. Oluyomi Stephen Adeyemi,David Adeiza Otohinoyi,Oluwakemi Josephine Awakan,Adebukola Anne Adeyanju.  (2018-10-26)  Cellular apoptosis of HFF cells by inorganic nanoparticles not susceptible to modulation by Toxoplasma gondii infection in vitro..  Toxicology in vitro : an international journal published in association with BIBRA,  54  (280-285).  [PMID:30359720]
20. Mahboubeh Yazdanifar,Ru Zhou,Priyanka Grover,Chandra Williams,Mukulika Bose,Laura J Moore,Shu-Ta Wu,John Maher,Didier Dreau,And Pinku Mukherjee.  (2019-09-14)  Overcoming Immunological Resistance Enhances the Efficacy of A Novel Anti-tMUC1-CAR T Cell Treatment against Pancreatic Ductal Adenocarcinoma..  Cells,  8  ((9)): [PMID:31514488]
21. Raul Castro-Portuguez,George L Sutphin.  (2020-01-20)  Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan..  Experimental gerontology,  132  (110841-110841).  [PMID:31954874]
22. Luiz Henrique Gomes Matheus,Stephanie Vanin Dalmazzo,Rodrigo Barbosa Oliveira Brito,Lucas Alves Pereira,Robson José de Almeida,Cleber Pinto Camacho,Humberto Dellê.  (2020-09-11)  1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression..  BMC cancer,  20  ((1)): (869-869).  [PMID:32907554]
23. Kuo-Ching Mei,Yu-Pei Liao,Jinhong Jiang,Michelle Chiang,Mercedeh Khazaieli,Xiangsheng Liu,Xiang Wang,Qi Liu,Chong Hyun Chang,Xiao Zhang,Juan Li,Ying Ji,Brenda Melano,Donatello Telesca,Tian Xia,Huan Meng,Andre E Nel.  (2020-09-18)  Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors..  ACS nano,  14  ((10)): (13343-13366).  [PMID:32940463]
24. Claudia Cantoni,Martina Serra,Erica Parisi,Bruno Azzarone,Angela Rita Sementa,Luigi Aurelio Nasto,Lorenzo Moretta,Giovanni Candiano,Cristina Bottino,Gian Marco Ghiggeri,Grazia Maria Spaggiari.  (2021-03-25)  Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells..  Oncoimmunology,  10  ((1)): (1879530-1879530).  [PMID:33758675]
25. Shoba Amarnath,Carliann M Costanzo,Jacopo Mariotti,Jessica L Ullman,William G Telford,Veena Kapoor,James L Riley,Bruce L Levine,Carl H June,Timothy Fong,Noel L Warner,Daniel H Fowler.  (2010-02-04)  Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1..  PLoS biology,  8  ((2)): (e1000302-e1000302).  [PMID:20126379]
26. Franco Carranza,Cristian Roberto Falcón,Nicolás Nuñez,Carolina Knubel,Silvia Graciela Correa,Ismael Bianco,Mariana Maccioni,Ricardo Fretes,María Fernanda Triquell,Claudia Cristina Motrán,Laura Cervi.  (2012-08-01)  Helminth antigens enable CpG-activated dendritic cells to inhibit the symptoms of collagen-induced arthritis through Foxp3+ regulatory T cells..  PloS one,  7  ((7)): (e40356-e40356).  [PMID:22848374]
27. Luciana Cavalheiro Marti,Lorena Pavon,Patricia Severino,Tatiana Sibov,Daiane Guilhen,Carlos Alberto Moreira-Filho.  (2013-10-22)  Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation..  Memorias do Instituto Oswaldo Cruz,  109  ((1)): (70-79).  [PMID:24141959]
28. Anle Zhang,Yuanhong Zheng,Zujun Que,Lingling Zhang,Shengchao Lin,Vanminh Le,Jianwen Liu,Jianhui Tian.  (2014-07-02)  Astragaloside IV inhibits progression of lung cancer by mediating immune function of Tregs and CTLs by interfering with IDO..  Journal of cancer research and clinical oncology,  140  ((11)): (1883-1890).  [PMID:24980548]
29. Allison Ehrlich,Tiago Moreno Castilho,Karen Goldsmith-Pestana,Wook-Jin Chae,Alfred L M Bothwell,Tim Sparwasser,Diane McMahon-Pratt.  (2014-08-08)  The immunotherapeutic role of regulatory T cells in Leishmania (Viannia) panamensis infection..  Journal of immunology (Baltimore, Md. : 1950),  193  ((6)): (2961-2970).  [PMID:25098291]
30. María I Cuartero,Iván Ballesteros,Juan de la Parra,Andrew L Harkin,Aine Abautret-Daly,Eoin Sherwin,Pedro Fernández-Salguero,Angel L Corbí,Ignacio Lizasoain,María A Moro.  (2014-11-02)  L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke..  Circulation,  130  ((23)): (2040-2051).  [PMID:25359166]
31. Kapil Chaudhary,Rahul Shinde,Haiyun Liu,Jaya P Gnana-Prakasam,Rajalakshmi Veeranan-Karmegam,Lei Huang,Buvana Ravishankar,Jillian Bradley,Nino Kvirkvelia,Malgorzata McMenamin,Wei Xiao,Daniel Kleven,Andrew L Mellor,Michael P Madaio,Tracy L McGaha.  (2015-05-17)  Amino acid metabolism inhibits antibody-driven kidney injury by inducing autophagy..  Journal of immunology (Baltimore, Md. : 1950),  194  ((12)): (5713-5724).  [PMID:25980011]
32. Holly C Lewis,Raghavan Chinnadurai,Steven E Bosinger,Jacques Galipeau.  (2017-12-02)  The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells..  Oncotarget,  8  ((54)): (91914-91927).  [PMID:29190885]
33. Oluyomi Stephen Adeyemi,Yuho Murata,Tatsuki Sugi,Yongmei Han,Kentaro Kato.  (2018-06-09)  Exploring Amino Acid-Capped Nanoparticles for Selective Anti-Parasitic Action and Improved Host Biocompatibility..  Journal of biomedical nanotechnology,  14  ((5)): (847-867).  [PMID:29883557]
34. Ewelina Rojewska,Katarzyna Ciapała,Anna Piotrowska,Wioletta Makuch,Joanna Mika.  (2018-07-28)  Pharmacological Inhibition of Indoleamine 2,3-Dioxygenase-2 and Kynurenine 3-Monooxygenase, Enzymes of the Kynurenine Pathway, Significantly Diminishes Neuropathic Pain in a Rat Model..  Frontiers in pharmacology,  9  (724-724).  [PMID:30050435]
35. Konstantin Knoblich,Sara Cruz Migoni,Susan M Siew,Elizabeth Jinks,Baksho Kaul,Hannah C Jeffery,Alfie T Baker,Muath Suliman,Katerina Vrzalikova,Hisham Mehenna,Paul G Murray,Francesca Barone,Ye H Oo,Philip N Newsome,Gideon Hirschfield,Deirdre Kelly,Steven P Lee,Biju Parekkadan,Shannon J Turley,Anne L Fletcher.  (2018-09-05)  The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation..  PLoS biology,  16  ((9)): (e2005046-e2005046).  [PMID:30180168]
36. Shicheng Su,Jinghua Zhao,Yue Xing,Xiaoqian Zhang,Jiang Liu,Qian Ouyang,Jianing Chen,Fengxi Su,Qiang Liu,Erwei Song.  (2018-10-06)  Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages..  Cell,  175  ((2)): (442-457).  [PMID:30290143]
37. Valeria Caffi,Gabriel Espinosa,Gonzalo Gajardo,Natalia Morales,María Carolina Durán,Benjamín Uberti,Gabriel Morán,Anita Plaza,Claudio Henríquez.  (2020-07-14)  Pre-conditioning of Equine Bone Marrow-Derived Mesenchymal Stromal Cells Increases Their Immunomodulatory Capacity..  Frontiers in veterinary science,  7  (318-318).  [PMID:32656251]
38. Xinpei Liu, Xuan Yi, Jingyu Gu, Zhongfang Ji, Minqian Zhu, Mengling Shen, Yuanyuan Ren, Li Guo, Teng Liu, Nan Ding, Kai Yang.  (2023)  Immunoregulatory liposomes hitchhiking on neutrophils for enhanced carbon ion radiotherapy-assisted immunotherapy of glioblastoma.  Nano Today,  53  (102037).  [10.1016/j.nantod.2023.102037]
39. Shikai Zhang, Qing Xu, Changbo Ji, Xiaoyu Han, Yang Zhou, Chao Liang, Linran Ma, Weijian Sun, Yanling Li, Zhengyou Yang, Fengchun Zhao, Yuan Tian.  (2023)  Study on secondary metabolites of endophytic fungus Diaporthe sp. AC1 induced by tryptophan analogs.  Frontiers in Microbiology,  14  (1254609).  [PMID:37876783] [10.3389/fmicb.2023.1254609]
40. Ping Huang, Yao Yang, Wenyan Wang, Zimu Li, Nansha Gao, Hongzhong Chen, Xiaowei Zeng.  (2023)  Self-driven nanoprodrug platform with enhanced ferroptosis for synergistic photothermal-IDO immunotherapy.  BIOMATERIALS,  299  (122157).  [PMID:37196407] [10.1016/j.biomaterials.2023.122157]
41. Li Xiangfei, Qiao Juan, Sun Yongjun, Li Zhiwei, Qi Li.  (2021)  Ligand-modulated synthesis of gold nanoclusters for sensitive and selective detection of folic acid.  Journal of Analytical Science and Technology,  12  (1): (1-8).  [10.1186/s40543-021-00266-6]
42. Qilin Li, Jia Liu, Huiling Fan, Lin Shi, Yan Deng, Lei Zhao, Mengxi Xiang, Yunruo Xu, Xulin Jiang, Guobin Wang, Lin Wang, Zheng Wang.  (2021)  IDO-inhibitor potentiated immunogenic chemotherapy abolishes primary tumor growth and eradicates metastatic lesions by targeting distinct compartments within tumor microenvironment.  BIOMATERIALS,  269  (120388).  [PMID:33172606] [10.1016/j.biomaterials.2020.120388]
43. Wenshuai Li, Saipeng Huang, Huiyun Wen, Yane Luo, Jiewei Cheng, Zhao Jia, Pu Han, Weiming Xue.  (2020)  Pyridine functionalized carbon dots for specific detection of tryptophan in human serum samples and living cells.  MICROCHEMICAL JOURNAL,  154  (104579).  [10.1016/j.microc.2019.104579]

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