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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| M109874-5g |
5g |
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| M109874-25g |
25g |
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| M109874-100g |
100g |
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| M109874-500g |
500g |
现货 ![]() |
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| 别名 | 2-甲基-5-硝基咪唑-1-乙醇 |
|---|---|
| 英文别名 | 2-(2-methyl-5-nitro-1-imidazolyl)ethanol | BAY-5360 | NSC69587 | NSC-69587 | Trimeks | Flagesol | Orvagil | Metronidazol | SC 10295 | 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole | Flagemona | Elyzol | Metronidazol [INN-Spanish] | EPA Pesticide Chemical Co |
| 规格或纯度 | Moligand™, ≥99% |
| 英文名称 | Metronidazole |
| 生化机理 | 硝基咪唑化合物具有抗寄生虫和抗菌活性。体内具有活性 |
| 应用 | Usually used to treat amebiasis, vaginitis, Trichomonas infections, giardiasis, anaerobic bacteria and treponemal infections. Metronidazole is used to study DNA damage and repair and has been found to induce the gene transfer agent VSH-1 in Brachyspira hyodysenteriae. It is commonly used for treatment of periodontitis and is used in bioavailability studies. |
| 储存温度 | 2-8°C储存,避光 |
| 运输条件 | 冰袋运输 |
| 备注 | 如果有可能,您尽量在使用的当天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
| 产品介绍 |
溶于热水,略溶于乙醇,微溶于水或氯仿,极微溶于乙醇。味苦而略咸。Usually used to treat amebiasis, vaginitis, Trichomonas infections, giardiasis, anaerobic bacteria and treponemal infections. Metronidazole is used to study DNA damage and repair and has been found to induce the gene transfer agent VSH-1 in Brachyspira hyodysenteriae. It is commonly used for treatment of periodontitis and is used in bioavailability studies. Usually used to treat amebiasis, vaginitis, Trichomonas infections, giardiasis, anaerobic bacteria and treponemal infections. Metronidazole is used to study DNA damage and repair and has been found to induce the gene transfer agent VSH-1 in Brachyspira hyodysenteriae. It is commonly used for treatment of periodontitis and is used in bioavailability studies. |
| 纯度 | ≥99% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 207-136-1 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 2-(2-methyl-5-nitroimidazol-1-yl)ethanol |
| INCHI | 1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3 |
| InChi Key | VAOCPAMSLUNLGC-UHFFFAOYSA-N |
| Smiles | CC1=NC=C(N1CCO)[N+](=O)[O-] |
| Isomeric SMILES | CC1=NC=C(N1CCO)[N+](=O)[O-] |
| 分子量 | 171.15 |
| Beilstein号 | 611683 |
| Reaxy-Rn | 611683 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=611683&ln= |
| 溶解性 | Soluble in water (10 mg/ml at 20°C), ethanol, methanol, chloroform, and dimethyl sulfoxide. |
|---|---|
| 密度 | 1.45 |
| 敏感性 | 对光线敏感 |
| 熔点 | 161°C |
| 分子量 | 171.150 g/mol |
| XLogP3 | 0.000 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 2 |
| 精确质量Exact Mass | 171.064 Da |
| 单同位素质量Monoisotopic Mass | 171.064 Da |
| 拓扑极表面积Topological Polar Surface Area | 83.900 Ų |
| 重原子数Heavy Atom Count | 12 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 170.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS08 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H302: 吞食有害 H312: 皮肤接触有害 H332: 吸入有害 H341: 怀疑引起遗传缺陷 H350: 可能导致癌症 H351: 怀疑引起遗传缺陷 H373: 通过长时间或反复暴露对器官造成损害 H412: 对水生生物有害并具有长期持续影响 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时,请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P273: 避免释放到环境中。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P281: 根据需要使用个人防护设备。 P321: 特殊处理(请参阅此标签上的...)。 P330: 漱口 P302+P352: 如皮肤沾染:用水充分清洗。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P203: 使用前,获取、阅读并遵守所有安全说明。 P301+P317: 如果被吞咽:请寻求医疗帮助。 P318: 如果暴露或担心,请就医。 P317: 寻求紧急医疗救助。 P319: 如果你感到不适,请寻求医疗帮助。 |
| WGK Germany | 3 |
| RTECS | NI5600000 |
| Merck Index | 6157 |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
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| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 | |
| 分析证书 | M109874 |
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| 2. Lee IK et al.. (2018) Regulation of CD4+CD8-CD25+ and CD4+CD8+CD25+ T cells by gut microbiota in chicken.. Sci Rep, 8 (8627). [PMID:29872084] |
| 3. Chao Nie, Yunyi Zhao, Pengjie Wang, Ran Wang, Yixuan Li, Xifan Wang, Bing Fang, Xiaoyu Wang, Jing Zhan, Longjiao Zhu, Chong Chen, Weibo Zhang, Haiping Liao, Rong Liu. (2024) Momordica charantia Polysaccharide intervention ameliorates the symptoms of dextran sulfate sodium (DSS)-induced colitis by modulating gut microbiota and inhibiting inflammation. Journal of Functional Foods, 112 (105970). [10.1016/j.jff.2023.105970] |
| 4. Huijie Duan, Junya Hu, Yang Deng, Junqing Zou, Wangli Ding, Qiang Peng, Rui Duan, Jianguo Sun, Junrong Zhu. (2024) Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice. Nutrients, 16 (1): (9). [PMID:38201839] [10.3390/nu16010009] |
| 5. Zhiwei Yang, Jing Zhang, Xixi Sun, Xinyu Wang, Yueqi Pan, Jiagang Wu, Xianchun Chen. (2024) Piezoelectric charges elicited a chain reaction of sulfite activation: Performance and mechanism. SEPARATION AND PURIFICATION TECHNOLOGY, 332 (125711). [10.1016/j.seppur.2023.125711] |
| 6. Yanqiu Zhang, Minrui Sun, Yang Lu, Mingguo Peng, Erdeng Du, Xia Xu. (2023) Nitrogen-Doped Carbon Dots Encapsulated a Polyoxomolybdate-Based Coordination Polymer as a Sensitive Platform for Trace Tetracycline Determination in Water. Nanomaterials, 13 (19): (2676). [PMID:37836317] [10.3390/nano13192676] |
| 7. Junping Zheng, Jianghui Hu, Yong Yang, Lei Xiong, Huabing Yang, Zhigang Zhang, Nan Jiang, Hongtao Liu. (2023) Suppressive effect of Tripterygium hypoglaucum (Levl.) Hutch extract on rheumatoid arthritis in mice by modulating inflammasome and bile acid metabolism. BIOMEDICINE & PHARMACOTHERAPY, 167 (115494). [PMID:37734264] [10.1016/j.biopha.2023.115494] |
| 8. Kai Wang, Xiaoyan Lu, Dedong Wu, Pengfei Xiao. (2023) Sustainable activation of sulfite by oxygen vacancies-enriched spherical Li3PO4-Co3O4 composite catalyst for efficient degradation of metronidazole. Journal of Environmental Chemical Engineering, 11 (111053). [10.1016/j.jece.2023.111053] |
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| 12. Huijiao Wang, Lingwei Gao, Yuxin Xie, Gang Yu, Yujue Wang. (2023) Clarification of the role of singlet oxygen for pollutant abatement during persulfate-based advanced oxidation processes: Co3O4@CNTs activated peroxymonosulfate as an example. WATER RESEARCH, 244 (120480). [PMID:37598568] [10.1016/j.watres.2023.120480] |
| 13. Kexin Yin, Yanan Shang, Dongdong Chen, Baoyu Gao, Qinyan Yue, Xing Xu. (2023) Redox potentials of pollutants determining the dominate oxidation pathways in manganese single-atom catalyst (Mn-SAC)/peroxymonosulfate system: Selective catalytic mechanisms for versatile pollutants. APPLIED CATALYSIS B-ENVIRONMENTAL, 338 (123029). [10.1016/j.apcatb.2023.123029] |
| 14. Liu Shuan, Dong Zhenlin, Tang Wenjie, Zhou Jian, Guo Liu, Gong Chengyan, Liu Guang, Wan Dan, Yin Yulong. (2023) Dietary iron regulates intestinal goblet cell function and alleviates Salmonella typhimurium invasion in mice. Science China-Life Sciences, (1-14). [PMID:37340176] [10.1007/s11427-022-2298-1] |
| 15. Yu-Ying Li, Feifan Guo, Jin Yang, Jian-Fang Ma. (2023) Efficient detection of metronidazole by a glassy carbon electrode modified with a composite of a cyclotriveratrylene-based metal–organic framework and multi-walled carbon nanotubes. FOOD CHEMISTRY, 425 (136482). [PMID:37285624] [10.1016/j.foodchem.2023.136482] |
| 16. Sun Qing, Hu Xiaofang, Zhao Yingjie, Zhang Jian, Sheng Jiawei. (2023) Construction of Co3O4 anchored on Bi2MoO6 microspheres for highly efficient photocatalytic peroxymonosulfate activation towards degradation of norfloxacin. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (30): (75247-75261). [PMID:37213017] [10.1007/s11356-023-27674-y] |
| 17. Qin Tang, Zhengcai Ma, Xiang Tang, Yan Liu, Huimin Wu, Yu Peng, Baihua Jiao, Rui Wang, Xiaoli Ye, Hang Ma, Xuegang Li. (2023) Coptisine inhibits Helicobacter pylori and reduces the expression of CagA to alleviate host inflammation in vitro and in vivo. JOURNAL OF ETHNOPHARMACOLOGY, (116618). [PMID:37164257] [10.1016/j.jep.2023.116618] |
| 18. Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1): (1-16). [PMID:37147641] [10.1186/s12916-023-02880-0] |
| 19. Lijuan Chen, Lin Guo, Susu Feng, Congcong Wang, Zhicheng Cui, Sijing Wang, Qingmiao Lu, Hang Chang, Bo Hang, Antoine M Snijders, Jian-Hua Mao, Yibing Lu, Dafa Ding. (2023) Fecal microbiota transplantation ameliorates type 2 diabetes via metabolic remodeling of the gut microbiota in db/db mice. BMJ Open Diabetes Research & Care, 11 (3): (e003282). [PMID:37253485] [10.1136/bmjdrc-2022-003282] |
| 20. Mengxue He, Aiyang Liu, Jiachen Shi, Yong-Jiang Xu, Yuanfa Liu. (2023) Multi-Omics Reveals the Effects of Cannabidiol on Gut Microbiota and Metabolic Phenotypes. Cannabis and Cannabinoid Research, [PMID:37098174] [10.1089/can.2022.0331] |
| 21. Xiaojun Hu, Renhan Dong, Sheng Huang, Yisheng Zeng, Wei Zhan, Xiaofang Gao, Dong Tian, Jian Peng, Jiewei Xu, Ting Wang, Yaying Zhang, Xiaohui Wang, Xiaoxia Zhang, Jin Liu, Bing Guang, Tai Yang. (2023) CDBN-YGXZ, a Novel Small-Molecule Drug, Shows Efficacy against Clostridioides difficile Infection and Recurrence in Mouse and Hamster Infection Models. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, [PMID:37052498] [10.1128/aac.01704-22] |
| 22. Zhiyuan Meng, Sen Yan, Wei Sun, Jin Yan, Miaomiao Teng, Ming Jia, Sinuo Tian, Zhiqiang Zhou, Wentao Zhu. (2023) Chlorothalonil induces obesity in mice by regulating host gut microbiota and bile acids metabolism via FXR pathways. JOURNAL OF HAZARDOUS MATERIALS, 452 (131310). [PMID:37003002] [10.1016/j.jhazmat.2023.131310] |
| 23. Wang Shanshan, Wen Qiuyu, Qin Yan, Xia Quan, Shen Chenlin, Song Shuai. (2023) Gut microbiota and host cytochrome P450 characteristics in the pseudo germ-free model: co-contributors to a diverse metabolic landscape. Gut Pathogens, 15 (1): (1-14). [PMID:36945019] [10.1186/s13099-023-00540-5] |
| 24. Ding Liu, Zhenkun Su, Bo Han, Kaisheng Xia, Chenggang Zhou, Qiang Gao. (2023) Cobalt–aluminum oxide clusters-embedded γ-Al2O3 nanosheets for peroxymonosulfate activation: Interfacial pH-buffering property to eliminate cobalt leaching and boost the catalytic activity. APPLIED CATALYSIS B-ENVIRONMENTAL, 330 (122555). [10.1016/j.apcatb.2023.122555] |
| 25. Kexin Yin, Ruixian Wu, Yanan Shang, Dongdong Chen, Zelin Wu, Xinhao Wang, Baoyu Gao, Xing Xu. (2023) Microenvironment modulation of cobalt single-atom catalysts for boosting both radical oxidation and electron-transfer process in Fenton-like system. APPLIED CATALYSIS B-ENVIRONMENTAL, 329 (122558). [10.1016/j.apcatb.2023.122558] |
| 26. Tianyao Shen, Xiaojing Wang, Jiaqin Li, Peng Xu, Chunyan Yang, Peng Wang, Guangshan Zhang. (2023) Introduction of oxygen vacancy to Bi2Mn4O10 supported by nickel foam for 1O2 dominated metronidazole degradation under dielectric barrier discharge plasma. APPLIED CATALYSIS B-ENVIRONMENTAL, 328 (122518). [10.1016/j.apcatb.2023.122518] |
| 27. Mengxue He, Jiachen Shi, Aiyang Liu, Yong-Jiang Xu, Yuanfa Liu. (2023) Antibiotic-induced gut microbiota dysbiosis altered host metabolism. Molecular Omics, 19 (4): (330-339). [PMID:36852671] [10.1039/D2MO00284A] |
| 28. Yang Xia, Wei Songrui, Ma Xilong, Gao Zhuwei, Huang Wei, Wang Dun, Liu Zhongxin, Wang Jieqiong. (2023) Core–shell CoTiO3@MnO2 heterostructure for the photothermal degradation of tetracycline. JOURNAL OF MATERIALS SCIENCE, 58 (8): (3551-3567). [10.1007/s10853-023-08180-5] |
| 29. Xianglong Tang, Zhen Wang, Yandong Xie, Yuyang Liu, Kun Yang, Taiping Li, Hong Shen, Mengjie Zhao, Juan Jin, Hong Xiao, Hongyi Liu, Ning Gu. (2023) Radiation-Triggered Selenium-Engineered Mesoporous Silica Nanocapsules for RNAi Therapy in Radiotherapy-Resistant Glioblastoma. ACS Nano, 17 (4): (4062–4076). [PMID:36759969] [10.1021/acsnano.3c00269] |
| 30. Yajie Cai, Xiaojiaoyang Li, Qi Han, Jinzhao Bai, Qi Zheng, Rong Sun, Runping Liu. (2023) Si–Ni-San improves experimental colitis by favoring Akkermensia colonization. JOURNAL OF ETHNOPHARMACOLOGY, 305 (116067). [PMID:36586523] [10.1016/j.jep.2022.116067] |
| 31. Ma Ning, Guo Pingting, Chen Jingyu, Qi Zengkai, Liu Chunchen, Shen Jiakun, Sun Yiwei, Chen Xiyue, Chen Guo-Qiang, Ma Xi. (2023) Poly-β-hydroxybutyrate alleviated diarrhea and colitis via Lactobacillus johnsonii biofilm-mediated maturation of sulfomucin. Science China-Life Sciences, 66 (7): (1569-1588). [PMID:36580163] [10.1007/s11427-022-2213-6] |
| 32. Ke Lan, Huabing Yang, Junping Zheng, Haiming Hu, Tianxiang Zhu, Xiaojuan Zou, Baifei Hu, Hongtao Liu. (2023) Poria cocos oligosaccharides ameliorate dextran sodium sulfate-induced colitis mice by regulating gut microbiota dysbiosis. Food & Function, 14 (2): (857-873). [PMID:36537246] [10.1039/D2FO03424G] |
| 33. Lili Qian, Qian Li, Zhenshan Ding, Kejun Luo, Jiamin Su, Jiawei Chen, Guangying Zhu, Zhihua Gan, Qingsong Yu. (2022) Prodrug Nanosensitizer Overcomes the Radiation Resistance of Hypoxic Tumor. ACS Applied Materials & Interfaces, 14 (51): (56454–56470). [PMID:36525559] [10.1021/acsami.2c14628] |
| 34. Jinglu Hu, Wencheng Jiao, Ziyan Tang, Chunqing Wang, Qi Li, Meng Wei, Shiyong Song, Lina Du, Yiguang Jin. (2023) Quercetin inclusion complex gels ameliorate radiation-induced brain injury by regulating gut microbiota. BIOMEDICINE & PHARMACOTHERAPY, 158 (114142). [PMID:36527844] [10.1016/j.biopha.2022.114142] |
| 35. Zichen Luo, Weichen Xu, Tianjie Yuan, Chen Shi, Tianzi Jin, Ying Chong, Jianjian Ji, Lili Lin, Jianya Xu, Ying Zhang, An Kang, Wei Zhou, Tong Xie, Liuqing Di, Jinjun Shan. (2023) Platycodon grandiflorus root extract activates hepatic PI3K/PIP3/Akt insulin signaling by enriching gut Akkermansia muciniphila in high fat diet fed mice. PHYTOMEDICINE, 109 (154595). [PMID:36610135] [10.1016/j.phymed.2022.154595] |
| 36. Jinxi Feng, Tiantian Zhang, Wen Yan, Jingxiang Sun, Shuanghong Tian, Zhili He, Ya Xiong. (2023) Piezocatalytic activities of SnO2/t-BaTiO3 film towards pollutant degradation: Understanding the performance of piezo-current response. SEPARATION AND PURIFICATION TECHNOLOGY, 307 (122834). [10.1016/j.seppur.2022.122834] |
| 37. Heng Zhao, Xiaolin Ma, Mingjie Lu, Fengting He, Feifei Lin, Yang Zhang, Jinqiang Zhang, Pei Dong, Chaocheng Zhao, Hongqi Sun. (2023) Melamine foam derived nitrogen and boron co-doped metal-free electrode for enhanced electro-Fenton degradation of metronidazole. CHEMICAL ENGINEERING JOURNAL, 455 (140593). [10.1016/j.cej.2022.140593] |
| 38. Wen Qiuyu, Yu Shen, Wang Shanshan, Qin Yan, Xia Quan, Wang Sheng, Chen Guanjun, Shen Chenlin, Song Shuai. (2022) Impact of intestinal microbiota on metabolic toxicity and potential detoxification of amygdalin. Frontiers in Microbiology, 13 [PMID:36504787] [10.3389/fmicb.2022.1030516] |
| 39. Na Zhao, Qiu-Gu Chen, Xiu Chen, Xue-Ting Liu, Fan Geng, Meng-Meng Zhu, Fu-Ling Yan, Zhi-Jun Zhang, Qing-Guo Ren. (2023) Intestinal dysbiosis mediates cognitive impairment via the intestine and brain NLRP3 inflammasome activation in chronic sleep deprivation. BRAIN BEHAVIOR AND IMMUNITY, 108 (98). [PMID:36427810] [10.1016/j.bbi.2022.11.013] |
| 40. Zhimei Wang, Yuehuan Zhang, Qing Chen, Xin Xiao, Carl Redshaw. (2023) Preparation of pelargonic acid vesicles and sustained drug release. Canadian Journal of Chemistry, 101 (2): [10.1139/cjc-2022-0075] |
| 41. Panpan Li, Yanjun Liu, Juan Zhao, Wenjie Pan, Yuan He, Shunzhe Fu, Yuanfa Liu, Yong-Jiang Xu. (2022) Salecan ameliorates liver injury by regulating gut microbiota and its metabolites. Food & Function, 13 (22): (11744-11757). [PMID:36281730] [10.1039/D2FO02210A] |
| 42. Shaojie Wu, Mingyang Li, Lili Xin, Hongming Long, Xiangpeng Gao. (2022) Simultaneously photocatalytic removal of Cr(VI) and metronidazole by asynchronous cross-linked modified sodium alginate. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 116 (339). [10.1016/j.jiec.2022.09.024] |
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