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L-精氨酸盐酸盐
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| L420636-1ml |
1ml |
现货  |
|
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基本描述
| 别名 | 盐酸精氨酸 |
|---|---|
| 英文别名 | (S)-2-Amino-5-guanidinopentanoic acid hydrochloride | L-ARGININE HCL | L-Arginine monohydrochloride, BioUltra, >=99.5% (AT) | NSC-203450 | ARGININE HYDROCHLORIDE [ORANGE BOOK] | ARGININE HYDROCHLORIDE [USAN] | L-ARGININE HYDROCHLORIDE [JAN] | H-Arg-OH.HCl |
| 规格或纯度 | 10mM in Water |
| 英文名称 | L-Arginine hydrochloride |
| 生化机理 | 一氧化氮合成酶的底物，可以转化为瓜氨酸和一氧化氮 (NO)。通过与一氧化氮相关的机理诱导胰岛素释放。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 激活剂 |
| 产品介绍 |
无气味。溶于水，微溶于热乙醇，不溶于乙醚。水溶液呈酸性。218℃时熔结，225℃时成固态。 |
关联靶点（人）
F2
Tclin
Thrombin
(11687 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
HTR2B
Tclin
Serotonin 2b (5-HT2b) receptor
(10323 活性数据)
TBXA2R
Tclin
Thromboxane A2 receptor
(5717 活性数据)
PDE4A
Tclin
Phosphodiesterase 4A
(1943 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
HRH3
Tclin
Histamine H3 receptor
(10389 活性数据)
KDR
Tclin
Vascular endothelial growth factor receptor 2
(20924 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| EC号 | 214-275-1 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride |
| INCHI | 1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1 |
| InChi Key | KWTQSFXGGICVPE-WCCKRBBISA-N |
| Smiles | Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O |
| Isomeric SMILES | C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl |
| 关联CAS | 15595-35-4 |
| 分子量 | 210.66 |
| Beilstein号 | 6099937 |
| Reaxy-Rn | 3631658 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3631658&ln= |
化学和物理性质
| 敏感性 | 对光敏感 |
|---|---|
| 比旋光度 | 23 ° (C=8, HCl(1+1)) |
| 熔点 | 226-230°C |
| 分子量 | 210.660 g/mol |
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 5 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 5 |
| 精确质量Exact Mass | 210.088 Da |
| 单同位素质量Monoisotopic Mass | 210.088 Da |
| 拓扑极表面积Topological Polar Surface Area | 128.000 Ų |
| 重原子数Heavy Atom Count | 13 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 176.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 1 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 2 |
安全和危险性（GHS）
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 |
| 预防措施声明 |
P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 |
| WGK Germany | 1 |
| Merck Index | 780 |
| 个人防护装备 | Eyeshields,Gloves |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
此产品的引用文献
引用文献
| 1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934] |
| 2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [10.1016/j.lwt.2021.111749] |
| 3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535] |
| 4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091] |
| 5. Qiang Zheng, Song-Lin Xu, Xin-Lin Guo, Chuan-Yu Wang, Meng-Die Ma, Jin-Fang Ge. (2025) Effects of melatonin on the pharmacokinetics and amino acid metabolism profile of vigabatrin in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY, (117247). [PMID:39884559] [10.1016/j.taap.2025.117247] |
| 6. Wang Jiteng, Zhang Jingyi, Li Xinyu, Xu Hanying Y., Yang Yeshun, Zhang Jiankun, Feng Wenping, Chen Qiang, Dong Fen, Han Tao. (2025) Metabolism of arginine in juvenile largemouth bass (Micropterus salmoides) after oral or intraperitoneal administration of arginine or its substrates. AMINO ACIDS, 57 (1): (1-15). [PMID:39945913] [10.1007/s00726-024-03436-z] |
| 7. Shuangshuang Wan, Wurui Liu, Qian Wu, Kepeng Wang, Yaocheng Li, Peihong Huang, Yu Wu, Yunfei Mu, Yulin Fan, Jun Tao, Jia Yao, Fei Peng, Yu Zou, Lianhui Wang, Zhiyao Yuan, Xianguang Ding. (2024) Nanobiohybrid Extracellular Vesicle Nanoreactor with Improving Metabolical Activity for Biocatalytic Therapy. ACS Nano, 18 (47): (32899-32909). [PMID:39536071] [10.1021/acsnano.4c12458] |
| 8. Yingjie Sun, Changheng Li, Xiaofei Deng, Wenjie Li, Xiaoyi Deng, Weiqi Ge, Miaoyuan Shi, Ying Guo, Yanxun V Yu, Hai-bing Zhou, Youngnam N Jin. (2024) Target protein identification in live cells and organisms with a non-diffusive proximity tagging system. eLife, (2024 Dec). [PMID:39728918] [10.7554/eLife.102667] |