| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| L110739-5g |
5g |
现货  |
|
| 别名 | 十二烷酸 |
|---|---|
| 英文别名 | ABL | C-1297 | CH3-(CH2)10-COOH | MLS002177807 | MLS002415737 | Dodecanoic (Lauric) acid | s4726 | FEMA No. 2614 | n-Dodecanoic acid | SMR001253907 | fatty acid 12:0 | HYDROFOL ACID 1255 OR 1295 | lauric acid | LAURIC ACID [MI] | Dodecanoic acid, >=99.5% |
| 规格或纯度 | Moligand™, Standard for GC, ≥99.5%(GC) |
| 英文名称 | Lauric acid |
| 应用 | A common saturated fatty acid compound. |
| 运输条件 | 常规运输 |
| 作用类型 | 激动剂 |
| 作用机制 | GPR84 的激动剂 |
| 产品介绍 |
Lauric Acid, a 12 carbon saturated fatty acid, has been shown to be incorporated into rat hepatocytes at a higher preference to other cellular lipids. Other murine studies have sμggested that this compound is a substrate for acylation of certain proteins. Saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFκB (nuclear factor κB) activation. Lauric Acid is a substrate of CYP4A11.A common saturated fatty acid compound. Lauric Acid, a 12 carbon saturated fatty acid, has been shown to be incorporated into rat hepatocytes at a higher preference to other cellular lipids. Other murine studies have suggested that this compound is a substrate for acylation of certain proteins. Saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFκB (nuclear factor κB) activation. Lauric Acid is a substrate of CYP4A11. |
| 纯度 | ≥99.5%(GC) |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 205-582-1 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | dodecanoic acid |
| INCHI | 1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14) |
| InChi Key | POULHZVOKOAJMA-UHFFFAOYSA-N |
| Smiles | CCCCCCCCCCCC(=O)O |
| Isomeric SMILES | CCCCCCCCCCCC(=O)O |
| 分子量 | 200.32 |
| Beilstein号 | 1099477 |
| Reaxy-Rn | 1099477 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1099477&ln= |
| 溶解性 | Soluble in water (0.5 mg/ml at 25 °C), ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and chloroform. |
|---|---|
| 密度 | 0.883 |
| 闪点(℉) | 348.8 °F |
| 闪点(℃) | 176 °C |
| 沸点 | 225°C |
| 熔点 | 44-46°C |
| 分子量 | 200.320 g/mol |
| XLogP3 | 4.200 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 2 |
| 可旋转键计数Rotatable Bond Count | 10 |
| 精确质量Exact Mass | 200.178 Da |
| 单同位素质量Monoisotopic Mass | 200.178 Da |
| 拓扑极表面积Topological Polar Surface Area | 37.300 Ų |
| 重原子数Heavy Atom Count | 14 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 132.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS05, GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H315: 引起皮肤刺激 H318: 造成严重的眼睛损伤 H319: 引起严重眼睛刺激 |
| 预防措施声明 |
P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 |
| WGK Germany | 1 |
| RTECS | OE9800000 |
| Merck Index | 5384 |
| 个人防护装备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
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