| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| K422880-1ml |
1ml |
现货  |
|
| 英文别名 | Cantrex | KANAMYCIN MONO SULFATE | Kannasyn | J80EX28SMQ | KANAMYCIN SULFATE [GREEN BOOK] | KANAMYCIN A SULFATE [MI] | Kanamytrex | Kanatrol | s2315 | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydro |
|---|---|
| 规格或纯度 | 10mM in Water |
| 英文名称 | Kanamycin sulfate |
| 生化机理 | 卡那霉素（又称卡那霉素 A）是一种氨基糖苷类抗生素，对革兰氏阳性和革兰氏阴性菌有效。它是蛋白质生物合成的抑制剂，作用于 30S 核糖体，导致对遗传密码的误读。氨基糖苷类抗生素。氨基糖苷类抗生素制剂，与细菌 30S 核糖体亚基不可逆转地结合。导致 t-RNA 读取错误。抑制蛋白质合成。在体内对需氧革兰阴性菌和某些分枝杆菌有活性。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
无臭；有引湿性。在水中易溶，在氯仿或乙醚中几乎不溶。单硫酸卡那霉素的１２％的水溶液的pH为７.０－－９.０；硫酸卡那霉素的３０％的水溶液的pH为６.０－－８.０。 Used in biotechnology applications to inhibit protein synthesis. Used as a selection agent for cells transformed with kanamycin B (neoR, kanR) resistance gene. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid |
| INCHI | 1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1 |
| InChi Key | OOYGSFOGFJDDHP-KMCOLRRFSA-N |
| Smiles | C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O |
| Isomeric SMILES | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N.OS(=O)(=O)O |
| 关联CAS | 70560-51-9 |
| UN Number | 2811 |
| Packing Group | III |
| 分子量 | 582.58 |
| Beilstein号 | 18(4)7631 |
| Reaxy-Rn | 18153648 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18153648&ln= |
| 比旋光度 | 117.5 ° (C=1, H2O) |
|---|---|
| 熔点 | 250°C(dec.)(lit.) |
| 分子量 | 582.600 g/mol |
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 13 |
| 氢键受体数Hydrogen Bond Acceptor Count | 19 |
| 可旋转键计数Rotatable Bond Count | 6 |
| 精确质量Exact Mass | 582.205 Da |
| 单同位素质量Monoisotopic Mass | 582.205 Da |
| 拓扑极表面积Topological Polar Surface Area | 366.000 Ų |
| 重原子数Heavy Atom Count | 38 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 720.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 15 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 2 |
| 象形图 | GHS08 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H360: 可能损害生育力或未出生的孩子 H360D: 可能会伤害未出生的孩子 |
| 预防措施声明 |
P201: 使用前获取特殊说明 P202: 在阅读并理解所有安全预防措施之前，不要进行操作。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P308+P313: 如接触到或有疑虑：求医/就诊。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 |
| RTECS | NZ3225030 |
| Class | 6.1 |
| Merck Index | 5281 |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
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