| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| J611300-5mg |
5mg |
期货  |
| |
| J611300-25mg |
25mg |
期货 |
|
| 规格或纯度 | Moligand™ |
|---|---|
| 英文名称 | JX35 |
| 作用机制 | 恶性疟原虫组蛋白去乙酰化酶 1 |
| 分子类型 | 未知 |
|---|---|
| IIUPAC Name | 2-{2-[(6-cyano-1-methyl-1H-indol-3-yl)methyl]-2,6-diazaspiro[3.4]octan-6-yl}-N-hydroxypyrimidine-5-carboxamide |
| INCHI | 1S/C22H23N7O2/c1-27-10-17(18-3-2-15(7-23)6-19(18)27)11-28-12-22(13-28)4-5-29(14-22)21-24-8-16(9-25-21)20(30)26-31/h2-3,6,8-10,31H,4-5,11-14H2,1H3,(H,26,30) |
| InChi Key | WBVFFDSDELAGSY-UHFFFAOYSA-N |
| Smiles | ONC(=O)c1cnc(N2CC3(CN(Cc4cn(C)c5c4ccc(C#N)c5)C3)CC2)nc1 |
| Isomeric SMILES | CN1C=C(C2=C1C=C(C=C2)C#N)CN3CC4(C3)CCN(C4)C5=NC=C(C=N5)C(=O)NO |
| PubChem CID | 162679550 |
| 1. Wang M, Tang T, Li R, Huang Z, Ling D, Zheng L, Ding Y, Liu T, Xu W, Zhu F et al.. (2022) Drug Repurposing of Quisinostat to Discover Novel Plasmodium falciparum HDAC1 Inhibitors with Enhanced Triple-Stage Antimalarial Activity and Improved Safety.. J Med Chem, 65 (5): (4156-4181). [PMID:35175762] |
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