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氢氧化六甲季铵 溶液

    级别和纯度:
  • ca. 25% in Water
有货

库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
H462921-25ml
25ml 现货 Stock Image
H462921-100ml
100ml 期货 Stock Image
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铵盐[相转移催化剂] (1)

基本描述

别名 六甲铵二氢氧化物 (约25%于水中) | N1,N1,N1,N6,N6,N-六甲基己烷-1,6-二铵二氧化物 (约25%于水中) | N,N,N,N',N',N'-六甲基六亚甲基二铵二氢氧化物 (约25%于水中)
英文别名 Hexamethonium Dihydroxide (ca. 25% in Water) | H1762 | Hexamethoniun | Q27288307 | 1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, hydroxide (1:2) | trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;dihydroxide | HEXAMETHONIUM HYDROXIDE | SCHEMBL178044 |
规格或纯度 ca. 25% in Water
英文名称 Hexamethonium hydroxide solution
储存温度 2-8°C储存,充氩
运输条件 冰袋运输

关联靶点(其它种属)

Chrna3 Neuronal acetylcholine receptor; alpha3/beta4 (1368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

分子类型 小分子
IIUPAC Name trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;dihydroxide
INCHI 1S/C12H30N2.2H2O/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H2/q+2;;/p-2
InChi Key GYLUMIIRFKDCKI-UHFFFAOYSA-L
Smiles C[N+](C)(C)CCCCCC[N+](C)(C)C.[OH-].[OH-]
Isomeric SMILES C[N+](C)(C)CCCCCC[N+](C)(C)C.[OH-].[OH-]
分子量 236.39
Reaxy-Rn 8169313
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8169313&ln=

化学和物理性质

密度 1.03
敏感性 对空气敏感;对热敏感
分子量 236.390 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 2
可旋转键计数Rotatable Bond Count 7
精确质量Exact Mass 236.246 Da
单同位素质量Monoisotopic Mass 236.246 Da
拓扑极表面积Topological Polar Surface Area 2.000 Ų
重原子数Heavy Atom Count 16
形式电荷Formal Charge 0
复杂度Complexity 121.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 3

安全和危险性(GHS)

象形图 GHS05
信号词 危险
危险声明

H314: 造成严重的皮肤灼伤和眼睛损伤

预防措施声明

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P264: 处理后要彻底洗手。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理(请参阅此标签上的...)。

P363: 再次使用之前,请清洗受污染的衣物。

P301+P330+P331: 如误吞咽:漱口。不要诱导呕吐。

P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P305+P354+P338: 如果进入眼睛:立即用水冲洗几分钟。取下隐形眼镜(如果有的话),并且操作简单。继续冲洗。

P302+P361+P354: 如果接触皮肤:立即脱掉所有被污染的衣服。立即用水冲洗几分钟。

P316: 立即寻求紧急医疗救助。

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找到6个结果

批号(Lot Number) 证书类型 货号
J2430419 分析证书 H462921
J2430420 分析证书 H462921
L2314320 分析证书 H462921
L2314321 分析证书 H462921
L2314327 分析证书 H462921
L2314328 分析证书 H462921

引用文献

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4. Lalah M Niane,Vincent Joseph,Aida Bairam.  (2012-04-13)  Systemic blockade of nicotinic and purinergic receptors inhibits ventilation and increases apnoea frequency in newborn rats..  Experimental physiology,  97  ((8)): (981-993).  [PMID:22496504]
5. Anna K Leal,Megan N Murphy,Gary A Iwamoto,Jere H Mitchell,Scott A Smith.  (2012-05-15)  A role for nitric oxide within the nucleus tractus solitarii in the development of muscle mechanoreflex dysfunction in hypertension..  Experimental physiology,  97  ((12)): (1292-1304).  [PMID:22581746]
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7. Petteri Rinne,Sanna Tikka,Satu Mäkelä,Tomi Streng,Eriika Savontaus.  (2012-09-18)  Hemodynamic actions and mechanisms of systemically administered α-MSH analogs in mice..  Peptides,  38  ((1)): (150-158).  [PMID:22982611]
8. Monalisa W Pereira,Paulo Correia-de-Sá,Wilson Alves-Do-Prado.  (2012-09-28)  Adenosine A(2A) receptor antagonists are broad facilitators of antinicotinic neuromuscular blockade monitored either with 2 Hz train-of-four or 50 Hz tetanic stimuli..  Clinical and experimental pharmacology & physiology,  39  ((10)): (869-877).  [PMID:23013133]
9. Simon Akerman,Philip R Holland,Oliver Summ,Michele P Lasalandra,Peter J Goadsby.  (2012-10-16)  A translational in vivo model of trigeminal autonomic cephalalgias: therapeutic characterization..  Brain : a journal of neurology,  135  ((Pt 12)): (3664-3675).  [PMID:23065481]
10. Kamila Shakarchi,Peter C Zachar,Michael G Jonz.  (2012-11-17)  Serotonergic and cholinergic elements of the hypoxic ventilatory response in developing zebrafish..  The Journal of experimental biology,  216  ((Pt 5)): (869-880).  [PMID:23155078]
11. R C Palheta,M T B Silva,H L G Barbosa,A D N Pinheiro,K V V Cardoso,J R V Graça,P J C Magalhães,R B Oliveira,A A Santos.  (2013-01-29)  Atrial stretch delays gastric emptying of liquids in awake rats..  Life sciences,  92  ((10)): (569-575).  [PMID:23352973]
12. H-Z Sun,S-Z Zhao,H-B Ai.  (2013-02-08)  Role of nitric oxide in the control of the gastric motility within the nucleus ambiguus of rats..  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,  63  ((6)): (623-629).  [PMID:23388478]
13. Anna Sommansson,Wan Salman Wan Saudi,Olof Nylander,Markus Sjöblom.  (2013-05-04)  Melatonin inhibits alcohol-induced increases in duodenal mucosal permeability in rats in vivo..  American journal of physiology. Gastrointestinal and liver physiology,  305  ((1)): (G95-G105).  [PMID:23639810]
14. T C Sia,S J Brookes,P G Dinning,D A Wattchow,N J Spencer.  (2013-10-12)  Peristalsis and propulsion of colonic content can occur after blockade of major neuroneuronal and neuromuscular transmitters in isolated guinea pig colon..  American journal of physiology. Gastrointestinal and liver physiology,  305  ((12)): (G933-G939).  [PMID:24113766]
15. Bart G Borghuis,Loren L Looger,Susumu Tomita,Jonathan B Demb.  (2014-05-03)  Kainate receptors mediate signaling in both transient and sustained OFF bipolar cell pathways in mouse retina..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  34  ((18)): (6128-6139).  [PMID:24790183]
16. Marcos T Kuroki,Pilar A Guzman,Gregory D Fink,John W Osborn.  (2011-11-25)  Time-dependent changes in autonomic control of splanchnic vascular resistance and heart rate in ANG II-salt hypertension..  American journal of physiology. Heart and circulatory physiology,  302  ((3)): (H763-H769).  [PMID:22114134]
17. Masanobu Mori,Tsukasa Yamamoto,Maki Kaseda,Sachiko Yamada,Hideyuki Itabashi.  (2012-02-04)  Capillary ion electrophoresis of inorganic anions and uric acid in human saliva using a polyvinyl alcohol coated capillary column and hexamethonium chloride as additive of background electrolyte..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  887-888  (1-7).  [PMID:22300546]
18. Yasuhiro Nishida,Megumi Tandai-Hiruma,Takehito Kemuriyama,Kohsuke Hagisawa.  (2012-02-04)  Long-term blood pressure control: is there a set-point in the brain?.  The journal of physiological sciences : JPS,  62  ((3)): (147-161).  [PMID:22302247]
19. Hiroshi Hanamoto,Hitoshi Niwa,Mitsutaka Sugimura,Yoshinari Morimoto.  (2012-03-06)  Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats..  International journal of oral science,  ((1)): (24-29).  [PMID:22388694]
20. Edward S Schelegle,William F Walby.  (2012-04-25)  Vagal afferents contribute to exacerbated airway responses following ozone and allergen challenge..  Respiratory physiology & neurobiology,  181  ((3)): (277-285).  [PMID:22525484]
21. P G Dinning,M Costa,S J Brookes,N J Spencer.  (2012-05-05)  Neurogenic and myogenic motor patterns of rabbit proximal, mid, and distal colon..  American journal of physiology. Gastrointestinal and liver physiology,  303  ((1)): (G83-G92).  [PMID:22556138]
22. Jasna Twynstra,Philip J Medeiros,James C Lacefield,Dwayne N Jackson,J Kevin Shoemaker.  (2012-06-21)  Y1R control of sciatic nerve blood flow in the Wistar Kyoto rat..  Microvascular research,  84  ((2)): (133-139).  [PMID:22713926]
23. Wen-Hsien Lu,Kai-Sheng Hsieh,Pei-Jung Lu,Yi-Shan Wu,Wen-Yu Ho,Chi-Cheng Lai,Jyh-Seng Wang,Luo-Ping Ger,Michael Hsiao,Ching-Jiunn Tseng.  (2013-02-08)  Hexamethonium reverses the lethal cardiopulmonary damages in a rat model of brainstem lesions mimicking fatal enterovirus 71 encephalitis..  Critical care medicine,  41  ((5)): (1276-1285).  [PMID:23388515]
24. W J Lavery,J W Kiel.  (2013-04-10)  Effects of head down tilt on episcleral venous pressure in a rabbit model..  Experimental eye research,  111  (88-94).  [PMID:23567205]
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溶液计算器