| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| H420382-1ml |
1ml |
现货  |
|
| 英文别名 | Hydroxyzine pamoate | 10246-75-0 | Hydroxyzine embonate | Hydroxyzine (pamoate) | Bobsule | Equipose | Hydroxyzine pamoate salt | Hy-Pam | NSC-757063 | MLS000028605 | M20215MUFR | Masmoran | Paxisitil | SMR000058728 | Atarax P | SR-01000003149 | EINECS 233-582-1 | UNII-M20215MUFR | Hydroxyz |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | Hydroxyzine pamoate salt |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 拮抗剂 |
| 作用机制 | 组胺 H1 受体拮抗剂 |
| 产品介绍 |
双羟萘酸羟嗪 (Hydroxyzine pamoate) 是一种组胺受体 H1拮抗剂。 Hydroxyzine pamoate is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative. |
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol |
| INCHI | 1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2 |
| InChi Key | ASDOKGIIKXGMNB-UHFFFAOYSA-N |
| Smiles | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O |
| Isomeric SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O |
| PubChem CID | 25096 |
| 分子量 | 763.27 |
| 分子量 | 763.300 g/mol |
|---|---|
| XLogP3 | |
| 氢键供体数Hydrogen Bond Donor Count | 5 |
| 氢键受体数Hydrogen Bond Acceptor Count | 10 |
| 可旋转键计数Rotatable Bond Count | 12 |
| 精确质量Exact Mass | 762.271 Da |
| 单同位素质量Monoisotopic Mass | 762.271 Da |
| 拓扑极表面积Topological Polar Surface Area | 151.000 Ų |
| 重原子数Heavy Atom Count | 55 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 945.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 2 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H302: 吞食有害 |
| 预防措施声明 |
P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P330: 漱口 P501: 将内容物/容器处理到。。。 P301+P317: 如果被吞咽：请寻求医疗帮助。 |
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