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乌洛托品(易制爆)

494篇引用文献 COA COA
    级别和纯度:
  • AR
    •
  • ≥99%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
H116380-100g
 100g 现货 Stock Image
H116380-500g
 500g 现货 Stock Image
H116380-5kg
 5kg 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
main product photo

基本描述

别名 六次甲基四胺 | 六亚甲基四胺
英文别名 CHEBI:6824 | EC 202-905-8 | Hexa (vulcanization accelerator) | Metenamina (INN-Spanish) | Formin (the heterocyclic compound) | 1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane | Herax UTS | Methenamine (USP/INN) | Methenaminum [INN-Latin] | 1,3,5,7-tetrazatricy
规格或纯度 AR, ≥99%
英文名称 Hexamethylenetetramine
运输条件 常规运输
产品介绍

可燃。如超过此熔点即升华并分解，但不熔融。升温至300℃时放出氰化氢，温度再升高时，则分解为甲烷、氢和氮。几乎无臭，味甜而苦。可溶于水和氯仿，难溶于四氯化碳、丙酮、苯和乙醚，不溶于石油醚。在弱酸溶液中分解为氨及甲醛。与火焰接触时，立即燃烧并产生无烟火焰。有挥发性.肝功能试验中配制麝香草酚浊度液，检定和测定物铋、铁、锰、钴、钍、铂和镁，检定锂、铁氰化物溴化物和碘化物，测定铜、铀、铍、碲等，气相色谱固定液(最高使用温度180℃，溶剂为氯仿)。
纯度 ≥99%

关联靶点（人）

F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 202-905-8
分子类型 小分子
IIUPAC Name 1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane
INCHI 1S/C6H12N4/c1-7-2-9-4-8(1)5-10(3-7)6-9/h1-6H2
InChi Key VKYKSIONXSXAKP-UHFFFAOYSA-N
Smiles C1N2CN3CN1CN(C2)C3
Isomeric SMILES C1N2CN3CN1CN(C2)C3
UN Number 1328
Packing Group III
分子量 140.19
Beilstein号 2018
Reaxy-Rn 2018
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2018&ln=

化学和物理性质

溶解性 溶于水、乙醇、氯仿、四氯化碳，不溶于乙醚、石油醚、芳烃。
密度 1.331
敏感性 对湿度敏感
闪点(℉) 482.0 °F
闪点(℃) 250°C
熔点 280°C
分子量 140.190 g/mol
XLogP3 0.300
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 4
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 140.106 Da
单同位素质量Monoisotopic Mass 140.106 Da
拓扑极表面积Topological Polar Surface Area 13.000 Ų
重原子数Heavy Atom Count 10
形式电荷Formal Charge 0
复杂度Complexity 84.800
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

一般危化品 一般危化品,易制爆
象形图 GHS02,   GHS07
信号词 警告
危险声明

H228: 易燃固体

H317: 可能引起皮肤过敏反应

H401: 对水生生物有毒
预防措施声明

P201: 使用前获取特殊说明

P210: 远离热源，热表面，火花，明火和其他点火源。 - 禁止抽烟。

P202: 在阅读并理解所有安全预防措施之前，不要进行操作。

P240: 地面/粘结容器和接收设备

P241: 使用防爆的[电气/通风/照明/.../]设备。

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P272: 被污染的工作服不允许离开工作场所

P273: 避免释放到环境中。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P302+P352: 如皮肤沾染：用水充分清洗。

P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。

P370+P378: 火灾时：使用干砂、干粉或抗醇泡沫灭火。

P405: 密闭存放

P501: 将内容物/容器处理到。。。
WGK Germany 1
RTECS MN4725000
Class 4.1
个人防护装备 Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到54个结果

批号(Lot Number) 证书类型 货号
I2504399 分析证书 H116380
E2528479 分析证书 H116380
E2528805 分析证书 H116380
E2528462 分析证书 H116380
E2516762 分析证书 H116380
E2516763 分析证书 H116380
G2518034 分析证书 H116380
D2515333 分析证书 H116380
D2515334 分析证书 H116380
D2515335 分析证书 H116380
A2513522 分析证书 H116380
A2513516 分析证书 H116380
A2513518 分析证书 H116380
K2426584 分析证书 H116380
K2426585 分析证书 H116380
H2430386 分析证书 H116380
H2430387 分析证书 H116380
H2430388 分析证书 H116380
G2429356 分析证书 H116380
G2429354 分析证书 H116380
G2429357 分析证书 H116380
D2423243 分析证书 H116380
D2423242 分析证书 H116380
D2423304 分析证书 H116380
B2401103 分析证书 H116380
B2401101 分析证书 H116380
B2401102 分析证书 H116380
L2304166 分析证书 H116380
L2313050 分析证书 H116380
L2304187 分析证书 H116380
L2304185 分析证书 H116380
L2304188 分析证书 H116380
L2304186 分析证书 H116380
H2312146 分析证书 H116380
H2312303 分析证书 H116380
H2312305 分析证书 H116380
E2317671 分析证书 H116380
E2317649 分析证书 H116380
E2317669 分析证书 H116380
A2314128 分析证书 H116380
A2314130 分析证书 H116380
A2314133 分析证书 H116380
L2219081 分析证书 H116380
K2221127 分析证书 H116380
J2222380 分析证书 H116380
J2222379 分析证书 H116380
J2222419 分析证书 H116380
G2207259 分析证书 H116380
G2207260 分析证书 H116380
G2207262 分析证书 H116380
C2201243 分析证书 H116380
C2201244 分析证书 H116380
C2201249 分析证书 H116380
A2220054 分析证书 H116380

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引用文献

1. P Restani,A R Restelli,C L Galli.  (1992-09-01)  Formaldehyde and hexamethylenetetramine as food additives: chemical interactions and toxicology..  Food additives and contaminants,  9  ((5)): (597-605).  [PMID:1298665]
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7. Zhao-Peng Deng,Li-Hua Huo,Hui Xu,Hui Zhao,Seik Weng Ng,Shan Gao.  (2011-01-08)  The first metal-organic framework containing an unprecedented in situ-generated C-substituted hexamethylenetetramine ligand..  Dalton transactions (Cambridge, England : 2003),  40  ((6)): (1224-1226).  [PMID:21212868]
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16. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong.  (2011-12-24)  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)..  PLoS computational biology,  7  ((12)): (e1002310-e1002310).  [PMID:22194678]
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18. Jianguo Hu,Fenghua Li,Kaikai Wang,Dongxue Han,Qixian Zhang,Junhua Yuan,Li Niu.  (2012-04-10)  One-step synthesis of graphene-AuNPs by HMTA and the electrocatalytical application for O2 and H2O2..  Talanta,  93  (345-349).  [PMID:22483921]
19. Anja P Mose,Michael D Lundov,Claus Zachariae,Torkil Menné,Niels K Veien,Grete Laurberg,Knud Kaaber,Christian Avnstorp,Klaus E Andersen,Evy Paulsen,Charlotte G Mørtz,Mette Sommerlund,Anne Danielsen,Jens Thormann,Ove Kristensen,Berit Kristensen,Bo L Andersen,Susanne Vissing,Niels H Nielsen,Jeanne D Johansen.  (2012-05-04)  Occupational contact dermatitis in painters: an analysis of patch test data from the Danish Contact Dermatitis Group..  Contact dermatitis,  67  ((5)): (293-297).  [PMID:22551399]
20. Ashika Odhav,Donald V Belsito.  (2012-06-02)  Is quaternium-15 a formaldehyde releaser? Correlation between positive patch test reactions to formaldehyde and quaternium-15..  Dermatitis : contact, atopic, occupational, drug,  23  ((1)): (39-43).  [PMID:22653068]
21. Canting Guo,Saied Ghadersohi,Gail M Kephart,Roger A Laine,David A Sherris,Hirohita Kita,Jens U Ponikau.  (2012-06-13)  Improving the detection of fungi in eosinophilic mucin: seeing what we could not see before..  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,  147  ((5)): (943-949).  [PMID:22687329]
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23. Ann Pontén,Kristiina Aalto-Korte,Tove Agner,Klaus E Andersen,Ana M Giménez-Arnau,Margarida Gonçalo,An Goossens,Jeanne D Johansen,Christophe J Le Coz,Howard I Maibach,Thomas Rustemeyer,Ian R White,Magnus Bruze.  (2012-10-06)  Patch testing with 2.0% (0.60 mg/cm 2) formaldehyde instead of 1.0% (0.30 mg/cm 2) detects significantly more contact allergy..  Contact dermatitis,  68  ((1)): (50-53).  [PMID:23035891]
24. Cecilia Svedman,Klaus E Andersen,F M Brandão,Derk P Bruynzeel,Thomas L Diepgen,Peter J Frosch,Thomas Rustemeyer,Ana Giménez-Arnau,Margarida Gonçalo,An Goossens,Jeanne Duus Johansen,Arto Lahti,Torkil Menné,Stefania Seidenari,Antonella Tosti,Jan E Wahlberg,Ian R White,John D Wilkinson,Martin Mowitz,Magnus Bruze.  (2012-10-09)  Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008..  Contact dermatitis,  67  ((5)): (312-314).  [PMID:23039007]
25. Bon San B Lee,Tushar Bhuta,Judy M Simpson,Jonathan C Craig.  (2012-10-19)  Methenamine hippurate for preventing urinary tract infections..  The Cochrane database of systematic reviews,  10  (CD003265-CD003265).  [PMID:23076896]
26. Jia-Ming Liu,Shu-Lian Jiang,Ma-Lin Cui,Li Jiao,Li-Hong Zhang,Zhi-Yong Zheng.  (2012-12-04)  Ultra-sensitive complex as phosphorescence probe for the determination of trace protein..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  102  (1-6).  [PMID:23201567]
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28. S G Paranjape,A V Turankar,S D Sontakke.  (2013-02-05)  Eradication of Helicobacter pylori. Can methenamine, an antimicrobial designed to be effective at an acidic pH, meet this challenge?.  Medical hypotheses,  80  ((4)): (507-507).  [PMID:23375409]
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481. Yingyan Ma, Yuan Ha, Liangqiang Chen, Ziqi An, Linzhuang Xing, Zhenni Wang, Zhimin Li.  (2024)  Electrochemically Induced Ru/CoOOH Synergistic Catalyst as Bifunctional Electrode Materials for Alkaline Overall Water Splitting.  Small,  (2311884).  [PMID:38412403] [10.1002/smll.202311884]
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486. Fei Lu, Bin Zhang, Lifeng Shen, Anjie Chen, Yuhe Chen, Yuxue Zhou, Xiuyun Zhang, Bitao Liu, Min Zhou.  (2025)  Enhancing the Kinetics of Glucose Electro-Oxidation by Modulating the Binding Energy of Hydroxyl on Cobalt-Based Catalysts.  INORGANIC CHEMISTRY,  64  (5): (2245-2255).  [PMID:39853310] [10.1021/acs.inorgchem.4c04195]
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489. Cong Wang, Gang Li, Zheng Huang, Anfeng Peng.  (2024)  Ethylene Oligomerization into Linear α-Olefins Catalyzed by VSB-5 without Alkyl-Aluminum Cocatalysts.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  63  (29): (13025-13036).  [10.1021/acs.iecr.4c01435]
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492. Zhidong Jin, Jinbo Zhao, Chuanzhi Chen, Huan Zhou, Nan Xiang, Fei Liu, Lin Liu, Jiurong Liu, Yue Mou, Lili Wu.  (2024)  Functional F-doped SnSx modified ZnOHF heterojunctions for efficient NO2 gas sensing.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  697  (134502).  [10.1016/j.colsurfa.2024.134502]
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498. Wei Guo, Zheng Zhang, Nian Li, Min Xi, Cui Liu, Shudong Zhang, Zhenyang Wang.  (2024)  Hollow flower-like TiO2@CsxWO3 hybrid for effective thermal management using a UV/NIR light absorbing shield strategy.  Journal of Materials Chemistry A,  [10.1039/D4TA06951J]
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512. Sheng Jiang, Xiong Zhao, Jinhua Zhang, Bin Fang, Hongqiang Chen, Li Ma, Zihan Ding, Jinjia Wei, Nanjing Hao.  (2024)  Metal-doped functional zinc oxide nanosheets as flexible piezoelectric generator for self-powered mechanical sensing.  SENSORS AND ACTUATORS A-PHYSICAL,  371  (115337).  [10.1016/j.sna.2024.115337]
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516. Saeed Ahmed, Mohammad A. H. Badsha, Mohammad Ehtisham Khan, Wahid Ali, Akbar Mohammad, Abdullateef H. Bashiri.  (2024)  Morphology controlled fabrication of porous magnesium oxide nanostructures for the efficient elimination of methyl orange.  International Journal of Materials Research,  115  (10): (773-780).  [10.1515/ijmr-2024-0093]
517. Fanqi Kong, Hongyue Yu, Lifei Gao, Enyun Xing, Yan Yu, Xiaofei Sun, Wenxing Wang, Dongyuan Zhao, Xiaomin Li.  (2024)  Multifunctional Hierarchical Nanoplatform with Anisotropic Bimodal Mesopores for Effective Neural Circuit Reconstruction after Spinal Cord Injury.  ACS Nano,  18  (20): (13333-13345).  [PMID:38717602] [10.1021/acsnano.4c03252]
518. Shen Tian, Jiawei Mei, Lisha Zhang, Senyan Wang, Yuhui Yuan, Jia Li, Hongjian Liu, Wanbo Zhu, Dongdong Xu.  (2024)  Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing.  Small,  (2407340).  [PMID:39360460] [10.1002/smll.202407340]
519. Rumin Liu, Kequan Xia, Tao Yu, Feng Gao, Qinghua Zhang, Liping Zhu, Zhizhen Ye, Shikuan Yang, Yaoguang Ma, Jianguo Lu.  (2024)  Multifunctional Smart Fabrics with Integration of Self-Cleaning, Energy Harvesting, and Thermal Management Properties.  ACS Nano,  18  (45): (31085-31097).  [PMID:39480157] [10.1021/acsnano.4c08324]
520. Kun Zhang, Ni Dan, Ruo-Yu Zhang, Jiaojiao Wei, Rui-Xue Tian, Yongfan Zhang, Hong-Ru Fu, Mei Qiu, Lu-Fang Ma, Shuang-Quan Zang.  (2025)  Multi-Stimuli-Responsive Circularly Polarized Luminescence with Handedness Inversion and Near-Infrared Phosphorescence in Chiral Metal-Organic Framework Platform for White Light Emission and Information Encryption.  Advanced Science,  (2502784).  [PMID:40091696] [10.1002/advs.202502784]
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525. Shenyu Lan, Chuan Yu, Yawen Peng, Xiaonan Hu, Wei Yan, Xiang Cui, Mingshan Zhu, Chunyang Zhai.  (2024)  Piezo-modulated interface field facilitating hydroxyl radical formation of SrTiO3/ZnO heterojunction for water purification.  CHEMICAL ENGINEERING JOURNAL,  499  (155862).  [10.1016/j.cej.2024.155862]
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