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2-羟基-4-甲氧基苯甲醛

13篇引用文献 COA COA
    级别和纯度:
  • ≥98%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
H106333-1g
 1g 现货 Stock Image
H106333-5g
 5g 现货 Stock Image
H106333-25g
 25g 现货 Stock Image
H106333-100g
 100g 现货 Stock Image
H106333-500g
 500g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
Amino Acid/Protein Metabolism (4559) Bacterial (5911) Metabolic Enzyme/Protease (4889) Tyrosinase (72) 醛 (398) 非杂环砌块 (8221)
main product photo

基本描述

别名 4-甲氧基水杨醛 | 2-羟基对甲氧基苯甲醛
英文别名 A835710 | InChI=1/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H | 2-Hydroxy-4-methoxybenazldehyde | 2-Hydroxy-p-anisaldehyde | 2N395P88LW | ghl.PD_Mitscher_leg0.298 | Salicylaldehyde, 4-methoxy- | EN300-24375 | Z188964138 | DTXSID1060970 | AC-24065 | Benz
规格或纯度 ≥98%
英文名称 2-Hydroxy-4-methoxybenzaldehyde
储存温度 充氩
运输条件 常规运输
产品介绍

2-Hydroxy-4-methoxybenzaldehyde is the main component of root bark essential oil of Periploca sepium Bunge.It is a potential tyrosinase inhibitor present in African medicinal plantsUsually used in the synthesis of Schiff base ligand.

2-Hydroxy-4-methoxybenzaldehyde is the main component of root bark essential oil of Periploca sepium Bunge.It is a potential tyrosinase inhibitor present in African medicinal plants
Usually used in the synthesis of Schiff base ligand.
纯度 ≥98%

关联靶点（人）

TRIM24 Tchem 转录中介因子1-alpha(Transcription intermediary factor 1-alpha) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TRIM33 Tchem E3 泛素蛋白连接酶 TRIM33(E3 ubiquitin-protein ligase TRIM33) (2 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TYR Tclin Tyrosinase (717 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TRIM33 Tchem E3 ubiquitin-protein ligase TRIM33 (162 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488184368
EC号 211-604-0
分子类型 小分子
IIUPAC Name 2-hydroxy-4-methoxybenzaldehyde
INCHI 1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3
InChi Key WZUODJNEIXSNEU-UHFFFAOYSA-N
Smiles COC1=CC(=C(C=C1)C=O)O
Isomeric SMILES COC1=CC(=C(C=C1)C=O)O
分子量 152.15
Beilstein号 1072443
Reaxy-Rn 1072443
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1072443&ln=

化学和物理性质

溶解性 Solubility in methanol is almost transparent. Insoluble in water.
密度 1.231
敏感性 对空气敏感
闪点(℉) 235.4 °F
闪点(℃) 113 °C
沸点 124°C/12mmHg
熔点 40-44°C
分子量 152.150 g/mol
XLogP3 1.500
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 2
精确质量Exact Mass 152.047 Da
单同位素质量Monoisotopic Mass 152.047 Da
拓扑极表面积Topological Polar Surface Area 46.500 Ų
重原子数Heavy Atom Count 11
形式电荷Formal Charge 0
复杂度Complexity 135.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
RTECS BZ2810000
个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

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找到27个结果

批号(Lot Number) 证书类型 货号
L2325200 分析证书 H106333
L2325201 分析证书 H106333
L2325202 分析证书 H106333
L2325203 分析证书 H106333
B2313065 分析证书 H106333
F2214802 分析证书 H106333
L2128231 分析证书 H106333
H2310313 分析证书 H106333
H2310296 分析证书 H106333
H2310308 分析证书 H106333
H2310487 分析证书 H106333
H2310582 分析证书 H106333
H2310608 分析证书 H106333
C1814037 分析证书 H106333
L2208373 分析证书 H106333
L2208376 分析证书 H106333
L2208904 分析证书 H106333
L2208364 分析证书 H106333
L2208372 分析证书 H106333
L2208377 分析证书 H106333
L2208387 分析证书 H106333
D2314067 分析证书 H106333
E1924011 分析证书 H106333
I2201568 分析证书 H106333
I2201569 分析证书 H106333
F2214725 分析证书 H106333
F2214809 分析证书 H106333

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可替换产品

  1. 2-溴-5-羟基-4-甲氧基苯甲醛
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    • ≥90%

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  2. 2-氯-3-羟基-4-甲氧基苯甲醛
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  4. 2-羟基-4-甲氧基苯甲醛
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此产品的引用文献

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引用文献

1. I Kubo,I Kinst-Hori.  (1999-03-20)  2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants..  Planta medica,  65  ((1)): (19-22).  [PMID:10083839]
2. Subban Nagarajan,Lingamallu Jagan Mohan Rao.  (2003-07-11)  Determination of 2-hydroxy-4-methoxybenzaldehyde in roots of Decalepis hamiltonii (Wight & Arn.) and Hemidesmus indicus R.Br..  Journal of AOAC International,  86  ((3)): (564-567).  [PMID:12852577]
3. Ken-ichi Nihei,Yoshiro Yamagiwa,Tadao Kamikawa,Isao Kubo.  (2004-01-27)  2-hydroxy-4-isopropylbenzaldehyde, a potent partial tyrosinase inhibitor..  Bioorganic & medicinal chemistry letters,  14  ((3)): (681-683).  [PMID:14741268]
4. Chao-Bin Xue,Li Zhang,Wan-Chun Luo,Xian-Ye Xie,Lin Jiang,Ting Xiao.  (2007-01-30)  3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors..  Bioorganic & medicinal chemistry,  15  ((5)): (2006-2015).  [PMID:17258462]
5. Anish Kundu,Adinpunya Mitra.  (2013-05-30)  Flavoring extracts of Hemidesmus indicus roots and Vanilla planifolia pods exhibit in vitro acetylcholinesterase inhibitory activities..  Plant foods for human nutrition (Dordrecht, Netherlands),  68  ((3)): (247-253).  [PMID:23715789]
6. Giancarlo Statti,Mariangela Marrelli,Filomena Conforti,Antonella Spagnoletti,Massimo Tacchini,Carmela Fimognari,Eleonora Brognara,Roberto Gambari,Gianni Sacchetti,Alessandra Guerrini.  (2015-03-11)  Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br..  Phytotherapy research : PTR,  29  ((6)): (857-863).  [PMID:25753739]
7. Zabiulla, V Vigneshwaran, A Begum Bushra, G S Pavankumar, B T Prabhakar, Shaukath Ara Khanum,.  (2017-09-02)  Design and synthesis of conjugated azo-hydrazone analogues using nano BF.  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,  ( 419-428 ).  [PMID:28863382]
8. Julien Tailhades,Hotake Takizawa,Michael J Gait,Don A Wellings,John D Wade,Yoshitsugu Aoki,Fazel Shabanpoor.  (2017-11-03)  Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs..  Frontiers in chemistry,  5  (81-81).  [PMID:29094037]
9. Francesca Bonvicini,Mariacaterina Lianza,Manuela Mandrone,Ferruccio Poli,Giovanna Angela Gentilomi,Fabiana Antognoni.  (2018-06-07)  Hemidesmus indicus (L.) R. Br. extract inhibits the early step of herpes simplex type 1 and type 2 replication..  The new microbiologica,  41  ((3)): (187-194).  [PMID:29874387]
10. Julia Greiser,Christian Kühnel,Helmar Görls,Wolfgang Weigand,Martin Freesmeyer.  (2018-06-21)  N,1,4-Tri(4-alkoxy-2-hydroxybenzyl)-DAZA: efficient one-pot synthesis and labelling with 68Ga for PET liver imaging in ovo..  Dalton transactions (Cambridge, England : 2003),  47  ((27)): (9000-9007).  [PMID:29923561]
11. Arunachalam Kannappan,Ramanathan Srinivasan,Arumugam Nivetha,Angusamy Annapoorani,Shunmugiah Karutha Pandian,Arumugam Veera Ravi.  (2019-06-24)  Anti-virulence potential of 2-hydroxy-4-methoxybenzaldehyde against methicillin-resistant Staphylococcus aureus and its clinical isolates..  Applied microbiology and biotechnology,  103  ((16)): (6747-6758).  [PMID:31230099]
12. Arunachalam Kannappan,Ravindran Durgadevi,Ramanathan Srinivasan,Ricardo José Lucas Lagoa,Issac Abraham Sybiya Vasantha Packiavathy,Shunmugiah Karutha Pandian,Arumugam Veera Ravi.  (2020-06-27)  2-Hydroxy-4-methoxybenzaldehyde from Hemidesmus indicus is antagonistic to Staphylococcus epidermidis biofilm formation..  Biofouling,  36  ((5)): (549-563).  [PMID:32586125]
13. P Giridhar,T Rajasekaran,S Nagarajan,G A Ravishankar.  (2004-07-28)  Production of 2-hydroxy-4-methoxybenzaldehyde in roots of tissue culture raised and acclimatized plants of Decalepis hamiltonii Wight & Arn., an endangered shrub endemic to Southern India and evaluation of its performance vis-a-vis plants from natural habitat..  Indian journal of experimental biology,  42  ((1)): (106-110).  [PMID:15274490]
14. K N Chidambara Murthy,T Rajasekaran,P Giridhar,G A Ravishankar.  (2006-11-30)  Antioxidant property of Decalepis hamiltonii Wight & Arn..  Indian journal of experimental biology,  44  ((10)): (832-837).  [PMID:17131914]
15. Rubén Córdoba,Nélida Salvador Tormo,Antonio Fernández Medarde,Joaquín Plumet.  (2007-05-18)  Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1..  Bioorganic & medicinal chemistry,  15  ((15)): (5300-5315).  [PMID:17507232]
16. Dipjyoti Chakraborty,Debabrata Sircar,Adinpunya Mitra.  (2007-11-21)  Phenylalanine ammonia-lyase-mediated biosynthesis of 2-hydroxy-4-methoxybenzaldehyde in roots of Hemidesmus indicus..  Journal of plant physiology,  165  ((10)): (1033-1040).  [PMID:18023917]
17. Jihua Wang,Hao Liu,Jianglin Zhao,Haifeng Gao,Ligang Zhou,Zhilong Liu,Yuanquan Chen,Peng Sui.  (2010-08-26)  Antimicrobial and antioxidant activities of the root bark essential oil of Periploca sepium and its main component 2-hydroxy-4-methoxybenzaldehyde..  Molecules (Basel, Switzerland),  15  ((8)): (5807-5817).  [PMID:20736908]
18. Belagihalli M Srikanta,Mysore A Harish Nayaka,Shylaja M Dharmesh.  (2010-12-28)  Inhibition of Helicobacter pylori growth and its cytotoxicity by 2-hydroxy 4-methoxy benzaldehyde of Decalepis hamiltonii (Wight & Arn); a new functional attribute..  Biochimie,  93  ((4)): (678-688).  [PMID:21185348]
19. Gholamreza Karimipour,Mehrorang Ghaedi,Reza Sahraei,Ali Daneshfar,Mehdi Nejati Biyareh.  (2011-08-13)  Modification of gold nanoparticle loaded on activated carbon with bis(4-methoxysalicylaldehyde)-1,2-phenylenediamine as new sorbent for enrichment of some metal ions..  Biological trace element research,  145  ((1)): (109-117).  [PMID:21837453]
20. Anish Kundu,Narendra Jawali,Adinpunya Mitra.  (2012-05-23)  Shikimate pathway modulates the elicitor-stimulated accumulation of fragrant 2-hydroxy-4-methoxybenzaldehyde in Hemidesmus indicus roots..  Plant physiology and biochemistry : PPB,  56  (104-108).  [PMID:22609460]
21. Ling Yan, Qing-Song Gu, Wen-Li Jiang, Min Tan, Zhi-Ke Tan, Guo-Jiang Mao, Fen Xu, Chun-Yan Li.  (2022)  Near-Infrared Fluorescent Probe with Large Stokes Shift for Imaging of Hydrogen Sulfide in Tumor-Bearing Mice.  ANALYTICAL CHEMISTRY,  94  (14): (5514–5520).  [PMID:35360906] [10.1021/acs.analchem.1c04169]
22. Yang Tian, Dong-Ye Zhou, Wen-Li Jiang, Zun-Pan She, Yongfei Li, Chun-Yan Li.  (2021)  Novel near-infrared fluorescence probe with large Stokes shift for monitoring CCl4-induced toxic hepatitis.  TALANTA,  223  (121720).  [PMID:33303166] [10.1016/j.talanta.2020.121720]
23. Qian Li, Xiaoman Zhu, Yanli Xie, Shilin Ren.  (2020)  2-Hydroxy-4-methoxybenzaldehyde inhibits the growth of Aspergillus flavus via damaging cell wall, cell membrane, manipulating respiration thus creating a promising antifungal effect on corn kernels.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  56  (1): (178-184).  [10.1111/ijfs.14617]
24. Wen-Xin Wang, Wen-Li Jiang, Yang Liu, Yongfei Li, Jin Zhang, Chun-Yan Li.  (2020)  Near-infrared fluorescence probe with a large stokes shift for visualizing hydrogen peroxide in ulcerative colitis mice.  SENSORS AND ACTUATORS B-CHEMICAL,  320  (128296).  [10.1016/j.snb.2020.128296]
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28. Li Qian, Wang Chong, Xiao Hongying.  (2024)  2-Hydroxy-4-methoxybenzaldehyde, a more effective antifungal aroma than vanillin and its derivatives against Fusarium graminearum, destroys cell membranes, inhibits DON biosynthesis, and performs a promising antifungal effect on wheat grains.  Frontiers in Microbiology,  15  [PMID:38468857] [10.3389/fmicb.2024.1359947]
29. Yingzhen Zhang, Juan Liu, Jun Xiao, Fu Li, Kunming Liu, Min Yang, Jinbiao Liu.  (2025)  A PET based colorimetric/fluorescent dual-signal probe for selective detection of hypochlorite in real water samples.  JOURNAL OF MOLECULAR STRUCTURE,  1322  (140568).  [10.1016/j.molstruc.2024.140568]
30. Kun Yao, Hua Liu, Binbin Fang, Congyang Xia, Lingmin Gu, Lin Fang, Haohao Zhu, Jie Pan, Guofu Zhang.  (2024)  Design and application of a novel “turn-on” fluorescent probe for imaging sulfite in living cells and inflammation models.  BIOORGANIC CHEMISTRY,  146  (107305).  [PMID:38537335] [10.1016/j.bioorg.2024.107305]
31. Gaowei Li, Shichao Jiang, Zongliang Zhang, Xiaoyin Liu, Kai Wu, Peng Liu, Mei Yang, Ting Zhou, Jiamei Xiao, Nini Xin, Xiaoyang Wu, Zhihong Chen, Jie Ding, Chengheng Wu, Dan Wei, Jing Sun, Aiping Tong, Hongsong Fan, Liangxue Zhou.  (2024)  Donor Substitution Engineering of Hemicyanine Nanoparticles to Reprogram the Tumor Microenvironment and Enhance Fn14-Targeted BiTE for Glioblastoma Photoimmunotherapy.  ADVANCED FUNCTIONAL MATERIALS,  (2413847).  [10.1002/adfm.202413847]
32. Jianwei Hou, Xinghai Hao, Jiali Xu, Geoffrey I.N. Waterhouse, Chunhua Ni, Zhiming Zhang, Liangmin Yu.  (2024)  Fluorescent zinc acrylate resins containing coumarin structures with enhanced antifouling performance.  PROGRESS IN ORGANIC COATINGS,  194  (108597).  [10.1016/j.porgcoat.2024.108597]
33. Yuyang Luo, Shiyu Zheng, Congcong Dong, Haojie Yu, Kunming Liu, Juanhua Li, Jinbiao Liu.  (2025)  Synthesis of a dual-response signal sensor and naked-eye recognition of hypochlorite in real water samples.  JOURNAL OF MOLECULAR STRUCTURE,  1320  (139652).  [10.1016/j.molstruc.2024.139652]

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