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G2328084
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乙醇酸
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| G434198-100g |
100g |
现货  |
|
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基本描述
| 英文别名 | DTXSID0025363 | Kyselina hydroxyoctova [Czech] | GlyPure 70 | EN300-19242 | Glycolic Acid, Crystal, Reagent | Kyselina glykolova | USEPA/OPP Pesticide Code: 000101 | CCRIS 9474 | FT-0612572 | HOCH2COOH | HO-CH2-COOH | 2-hydroxyl ethanoic acid | GLYCOLIC A |
|---|---|
| 规格或纯度 | 适用于分析, 优级品 |
| 英文名称 | Glycolic acid |
| 储存温度 | 室温 |
| 运输条件 | 常规运输 |
| 产品介绍 |
乙醇酸（羟基乙酸）已用于制备PLGA-PEG-PLGA共聚物（PLGA = 聚乳酸聚乙醇酸共聚物，PEG =聚乙二醇）。
|
关联靶点（人）
PDE5A
Tclin
Phosphodiesterase 5A
(5113 活性数据)
EGFR
Tclin
Epidermal growth factor receptor erbB1
(33727 活性数据)
F2
Tclin
Thrombin
(11687 活性数据)
CA2
Tclin
Carbonic anhydrase II
(17698 活性数据)
ESR1
Tclin
Estrogen receptor alpha
(17718 活性数据)
HMGCR
Tclin
HMG-CoA reductase
(2475 活性数据)
NR3C1
Tclin
Glucocorticoid receptor
(14987 活性数据)
INSR
Tclin
Insulin receptor
(5558 活性数据)
PGR
Tclin
Progesterone receptor
(8562 活性数据)
ADRB2
Tclin
Beta-2 adrenergic receptor
(11824 活性数据)
CHRM2
Tclin
Muscarinic acetylcholine receptor M2
(10671 活性数据)
ADRB1
Tclin
Beta-1 adrenergic receptor
(6630 活性数据)
HTR1A
Tclin
Serotonin 1a (5-HT1a) receptor
(14969 活性数据)
ADRA2A
Tclin
Alpha-2a adrenergic receptor
(9450 活性数据)
AR
Tclin
Androgen Receptor
(11781 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
ACE
Tclin
Angiotensin-converting enzyme
(1423 活性数据)
DRD2
Tclin
Dopamine D2 receptor
(23596 活性数据)
GABRA1
Tclin
GABA receptor alpha-1 subunit
(399 活性数据)
MAOA
Tclin
Monoamine oxidase A
(11911 活性数据)
CNR1
Tclin
Cannabinoid CB1 receptor
(20913 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
DRD4
Tchem
Dopamine D4 receptor
(7907 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
PTGS1
Tclin
Cyclooxygenase-1
(9233 活性数据)
SLC6A2
Tclin
Norepinephrine transporter
(10102 活性数据)
HRH2
Tclin
Histamine H2 receptor
(5428 活性数据)
ADRA1D
Tclin
Alpha-1d adrenergic receptor
(4171 活性数据)
HTR1B
Tclin
Serotonin 1b (5-HT1b) receptor
(2801 活性数据)
HTR2A
Tclin
Serotonin 2a (5-HT2a) receptor
(14758 活性数据)
HTR2C
Tclin
Serotonin 2c (5-HT2c) receptor
(11471 活性数据)
ADORA1
Tclin
Adenosine A1 receptor
(17603 活性数据)
CALCR
Tclin
Calcitonin receptor
(2215 活性数据)
SLC6A4
Tclin
Serotonin transporter
(12625 活性数据)
ADRA1A
Tclin
Alpha-1a adrenergic receptor
(8359 活性数据)
PTGS2
Tclin
Cyclooxygenase-2
(13999 活性数据)
HRH1
Tclin
Histamine H1 receptor
(7573 活性数据)
ADRA1B
Tclin
Alpha-1b adrenergic receptor
(2912 活性数据)
OPRM1
Tclin
Mu opioid receptor
(19785 活性数据)
DRD3
Tclin
Dopamine D3 receptor
(14368 活性数据)
AVPR1A
Tclin
Vasopressin V1a receptor
(5412 活性数据)
OPRD1
Tclin
Delta opioid receptor
(15096 活性数据)
OPRK1
Tclin
Kappa opioid receptor
(16155 活性数据)
SLC6A3
Tclin
Dopamine transporter
(10535 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
HTR4
Tclin
Serotonin 4 (5-HT4) receptor
(2068 活性数据)
PDE3A
Tclin
Phosphodiesterase 3A
(3309 活性数据)
ESR2
Tclin
Estrogen receptor beta
(9272 活性数据)
CYSLTR1
Tclin
Cysteinyl leukotriene receptor 1
(2118 活性数据)
ERBB2
Tclin
Receptor protein-tyrosine kinase erbB-2
(7851 活性数据)
关联靶点（其它种属）
Agtr2
Angiotensin II type 2 (AT-2) receptor (803 活性数据)
Mc4r
Melanocortin receptor 4 (1205 活性数据)
Ltc4s
Leukotriene C4 synthase (1 活性数据)
Sigmar1
Sigma opioid receptor (160 活性数据)
Npy1r
Neuropeptide Y receptor type 1 (8 活性数据)
Cckar
Cholecystokinin A receptor (90 活性数据)
Nos2
Nitric oxide synthase, inducible (3573 活性数据)
Mapk1
MAP kinase ERK2 (650 活性数据)
Mmp9
Matrix metalloproteinase 9 (38 活性数据)
Glra2
Glycine receptor (1745 活性数据)
SARS-CoV-2 (38078 活性数据)
citA
Putative citrate synthase 2 (14 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| EC号 | 201-180-5 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 2-hydroxyacetic acid |
| INCHI | 1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5) |
| InChi Key | AEMRFAOFKBGASW-UHFFFAOYSA-N |
| Smiles | C(C(=O)O)O |
| Isomeric SMILES | C(C(=O)O)O |
| UN Number | 3261 |
| 分子量 | 76.05 |
| Beilstein号 | 1209322 |
| Reaxy-Rn | 1209322 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209322&ln= |
化学和物理性质
| 溶解性 | 水：可溶于20°C |
|---|---|
| 密度 | 1.49g/cm3at 25°C |
| 折光率 | 1.41 |
| 沸点 | 100°C |
| 熔点 | 72-80°C |
| 分子量 | 76.050 g/mol |
| XLogP3 | -1.100 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 76.016 Da |
| 单同位素质量Monoisotopic Mass | 76.016 Da |
| 拓扑极表面积Topological Polar Surface Area | 57.500 Ų |
| 重原子数Heavy Atom Count | 5 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 40.200 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
安全和危险性（GHS）
| 象形图 | GHS05, GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H302: 吞食有害 H314: 造成严重的皮肤灼伤和眼睛损伤 H318: 造成严重的眼睛损伤 H332: 吸入有害 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P363: 再次使用之前，请清洗受污染的衣物。 P301+P330+P331: 如误吞咽：漱口。不要诱导呕吐。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P405: 密闭存放 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。 P317: 寻求紧急医疗救助。 P302+P361+P354: 如果接触皮肤：立即脱掉所有被污染的衣服。立即用水冲洗几分钟。 P316: 立即寻求紧急医疗救助。 |
| WGK Germany | 1 |
| RTECS | MC5250000 |
| Merck Index | 4498 |
| 个人防护装备 | Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
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硫代乙醇酸（TGA）
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此产品的引用文献
引用文献
| 1. Dongao Zhu, Lixian Xu, Beibei Zhang, Linhua Zhu, Jing He, Hongping Li, Huaming Li, Wei Jiang. (2023) Designing Inorganic–Organic Dual-Acid Deep Eutectic Solvents for Synergistically Enhanced Extractive and Oxidative Desulfurization. MOLECULES, 28 (23): (7743). [PMID:38067473] [10.3390/molecules28237743] |
| 2. Xiaomei Ning, Liang Zhan, Xiaosong Zhou, Jin Luo, Yanli Wang. (2024) In-situ Bi-modified Pt towards glycerol and formic acid electro-oxidation: Effects of catalyst structure and surface microenvironment on activity and selectivity. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 655 (920). [PMID:37979297] [10.1016/j.jcis.2023.11.075] |
| 3. Meng Xia, Zheng Shen, Shaoze Xiao, Minyan Gu, Yalei Zhang. (2023) Synergistic effects of bimetals and hierarchical structures in Mg–Sn-Beta-H zeolites for lactic acid synthesis from biomass-derived carbohydrates. Catalysis Science & Technology, 13 (13): (3974-3986). [10.1039/D3CY00471F] |
| 4. Ji Cheng, Zhang Chengcheng, Xu Zeya, Chen Yan, Gan Yanming, Zhou Minghui, Li Lan, Duan Qinying, Huang Tingting, Lin Jinxin. (2023) Mussel-inspired HA@TA-CS/SA biomimetic 3D printed scaffolds with antibacterial activity for bone repair. Frontiers in Bioengineering and Biotechnology, 11 [PMID:37229495] [10.3389/fbioe.2023.1193605] |
| 5. Xiaoyuan Liu, Yu Zou, Jiang Jiang. (2023) Selective aerobic photocatalytic glycerol oxidation on Au/TiO2 with borate additives. APPLIED CATALYSIS A-GENERAL, 660 (119216). [10.1016/j.apcata.2023.119216] |
| 6. Feng Du, Mengyu Wang, Libin Wang, Yushan Li, Yuangao Wang, Wenan Deng, Wenjuan Yan, Xin Jin. (2023) Catalytic conversion of polyoxymethylene with bio-derived substrates: kinetic modeling on solvent enhancement effect and experimental studies on reaction mechanism. CHEMICAL ENGINEERING SCIENCE, 274 (118670). [10.1016/j.ces.2023.118670] |
| 7. Yiru Gao, Wenxin Zhang, Rong Xue, Yang Shu, Jianhua Wang. (2023) An ionic gel incorporating copper nanodots with antibacterial and antioxidant dual functions for deep tissue penetration treatment of periodontitis in rats. Biomaterials Science, 11 (10): (3547-3560). [PMID:37000509] [10.1039/D3BM00309D] |
| 8. Ernest Pahuyo Delmo, Yian Wang, Shangqian Zhu, Tiehuai Li, Yinuo Wang, Juhee Jang, Qinglan Zhao, Alexander Perez Roxas, Gabriel Sikukuu Nambafu, Zhengtang Luo, Lu-Tao Weng, Minhua Shao. (2023) The Role of Glyoxal as an Intermediate in the Electrochemical CO2 Reduction Reaction on Copper. Journal of Physical Chemistry C, 127 (9): (4496–4510). [10.1021/acs.jpcc.3c00589] |
| 9. Tao Sun, Junxia Bian, Yangyang Wang, Jian Hu, Xueyan Yun, Eerdunbayaer Chen, Tungalag Dong. (2023) One-Step Synthesis of Poly(L-Lactic Acid)-Based Soft Films with Gas Permselectivity for White Mushrooms (Agaricus bisporus) Preservation. Foods, 12 (3): (586). [PMID:36766115] [10.3390/foods12030586] |
| 10. Fenfen Wang, Dongxue Qu, Shaoshuai Wang, Guojun Liu, Qiang Zhao, Jiaxue Hu, Wendi Dong, Yong Huang, Jinjia Xu, Yuhui Chen. (2022) Bismuth-Decorated Beta Zeolites Catalysts for Highly Selective Catalytic Oxidation of Cellulose to Biomass-Derived Glycolic Acid. International Journal of Environmental Research and Public Health, 19 (23): (16298). [PMID:36498370] [10.3390/ijerph192316298] |
| 11. Yongfang Zhou, Thomas J.A. Slater, Xuanli Luo, Yi Shen. (2023) A versatile single-copper-atom electrocatalyst for biomass valorization. APPLIED CATALYSIS B-ENVIRONMENTAL, 324 (122218). [10.1016/j.apcatb.2022.122218] |
| 12. Tianqi Niu, Fuchao Zhen, Yue-Min Xie, Tinghuan Yang, Qin Yao, Jing Lu, Kui Zhao, Hin-Lap Yip. (2022) Molecularly Functionalized SnO2 Films by Carboxylic Acids for High-Performance Perovskite Solar Cells. ACS Applied Materials & Interfaces, 14 (47): (52838–52848). [PMID:36383432] [10.1021/acsami.2c14494] |
| 13. Qin Chang, Dong Jing, Xie Beibei, Wang Hongkun, Zhang Na, Zhao Chunhua, Qiao Congde, Liu Mingxia, Yang Xiaodeng, Li Tianduo. (2023) Synthesis, Characterization and Application of Poly(lactic-co-glycolic acid) with a Mass Ratio of Lactic to Glycolic Segments of 52/48. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 39 (2): (290-295). [10.1007/s40242-022-2226-3] |
| 14. Xiyang Wang, Siraj Ullah, Shuozhen Hu, Xinsheng Zhang. (2022) Investigation and Separation of Chromogenic Substances in Glyoxylic Acid Generated by Electrochemical Reduction of Oxalic Acid. ChemistrySelect, 7 (27): (e202201140). [10.1002/slct.202201140] |
| 15. Haitao Yu, Zhimin Xue, Ruifen Shi, Fengyi Zhou, Tiancheng Mu. (2022) Lignin dissolution and lignocellulose pretreatment by carboxylic acid based deep eutectic solvents. INDUSTRIAL CROPS AND PRODUCTS, 184 (115049). [10.1016/j.indcrop.2022.115049] |
| 16. Dan Yang, Xuan Liu, Fei Song, Yihu Dai, Xiaoyue Wan, Chunmei Zhou, Yanhui Yang. (2022) Chemoselective Oxidation of Glycerol over Platinum-Based Catalysts: Toward the Role of Oxide Promoter. ChemCatChem, 14 (10): (e202200011). [10.1002/cctc.202200011] |
| 17. Zhong-Lei Meng, Ru-Si Wen, Xiao-Rui Huang, Rong-Xiu Qin, Yi-Ming Hu, Yong-Hong Zhou. (2022) Synthesis of Terpineol from Alpha-Pinene Catalyzed by α-Hydroxy Acids. MOLECULES, 27 (3): (1126). [PMID:35164391] [10.3390/molecules27031126] |
| 18. Xinyu Wang, Baoyou Liu, Huilong Yang, Jie Tian. (2022) Properties of binary mixtures of a novel natural deep eutectic solvent (glycolic acid + xylitol) and water at several temperatures. FLUID PHASE EQUILIBRIA, 556 (113390). [10.1016/j.fluid.2022.113390] |
| 19. Kangling Yin, Li Chen, Feng Liu, Taotao Fan, Zongcheng Yan. (2022) Pseudoternary Systems of Deep Eutectic Solvents + tert-Butanol + Water at T = 288.15 K, 298.15 K, and 308.15 K: Liquid–Liquid Equilibrium and Ability for Syringic Acid/Eugenol Separation. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (1): (200–211). [10.1021/acs.jced.1c00802] |
| 20. Shuang Cao, Ning Sui, Peng Zhang, Tingting Zhou, Jinchun Tu, Tong Zhang. (2022) TiO2 nanostructures with different crystal phases for sensitive acetone gas sensors. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 607 (357). [PMID:34509110] [10.1016/j.jcis.2021.08.215] |
| 21. Haipeng Jiang, Xin Qu, Li He, Zheng Lv, Dan Li, Fengyou Wang, Lin Fan, Jinghai Yang, Lili Yang, Yongsheng Yan. (2022) A design strategy of additive molecule for PSCs: Anchoring intrinsic properties of functional groups by suppressing long-range conjugation effect. CHEMICAL ENGINEERING JOURNAL, 427 (131676). [10.1016/j.cej.2021.131676] |
| 22. Zhiyan He, Guangxing Yang, Hongjuan Wang, Fengying Dai, Feng Peng, Hao Yu. (2020) Co–N–C-Supported Platinum Catalyst: Synergistic Effect on the Aerobic Oxidation of Glycerol. ACS Sustainable Chemistry & Engineering, 8 (51): (19062–19071). [10.1021/acssuschemeng.0c07332] |
| 23. Yi-Hu Ke, Xue Wang, Hong-Yu Qin, Hai Liu, Hong Yuan, Chun-Ling Liu, Wen-Sheng Dong. (2020) Cu–Al composite oxides: a highly efficient support for the selective oxidation of glycerol to 1,3-dihydroxyacetone. NEW JOURNAL OF CHEMISTRY, 44 (42): (18173-18184). [10.1039/D0NJ02967J] |
| 24. Jing Ling, Suqin Gong, Yunsheng Xia. (2020) Monodisperse Fe2O3 Supraparticles: Eco-Friendly Fabrication, Gallic Acid Modification, Size-Dependent Photothermal Conversion Efficiency, and Cellular Uptake. Advanced Materials Interfaces, 7 (18): (2000804). [10.1002/admi.202000804] |
| 25. He Ma, Changhua Wang, Songmei Li, Xintong Zhang, Yichun Liu. (2020) High-humidity tolerance of porous TiO2(B) microspheres in photothermal catalytic removal of NOx. CHINESE JOURNAL OF CATALYSIS, 41 (1622). [10.1016/S1872-2067(19)63508-4] |
| 26. C.Q. Zhao, W.G. Liu, Z.Y. Xu, J.G. Li, T.T. Huang, Y.J. Lu, H.G. Huang, J.X. Lin. (2020) Chitosan ducts fabricated by extrusion-based 3D printing for soft-tissue engineering. CARBOHYDRATE POLYMERS, 236 (116058). [PMID:32172873] [10.1016/j.carbpol.2020.116058] |
| 27. Wang Zhen, Hu Jinhua, Yu Jiakang, Chen Daquan. (2020) Preparation and Characterization of Nano-Laponite/PLGA Composite Scaffolds for Urethra Tissue Engineering. MOLECULAR BIOTECHNOLOGY, 62 (3): (192-199). [PMID:32016781] [10.1007/s12033-020-00237-z] |
| 28. Yihu Ke, Xiaohua Li, Jifan Li, Chun-Ling Liu, Chunli Xu, Wen-Sheng Dong. (2019) Conversion of glycerol to dihydroxyacetone over Au catalysts on various supports. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 95 (4): (1153-1162). [10.1002/jctb.6300] |
| 29. Meng Xia, Zheng Shen, Shaoze Xiao, Bo-yu Peng, Minyan Gu, Wenjie Dong, Yalei Zhang. (2019) Synergistic effects and kinetic evidence of a transition metal-tin modified Beta zeolite on conversion of Miscanthus to lactic acid. APPLIED CATALYSIS A-GENERAL, 583 (117126). [10.1016/j.apcata.2019.117126] |
| 30. Han Hu, Ruoyu Zhang, Jinggang Wang, Wu Bin Ying, Lei Shi, Chenkai Yao, Zhengyang Kong, Kai Wang, Jin Zhu. (2019) A mild method to prepare high molecular weight poly(butylene furandicarboxylate-co-glycolate) copolyesters: effects of the glycolate content on thermal, mechanical, and barrier properties and biodegradability. GREEN CHEMISTRY, 21 (11): (3013-3022). [10.1039/C9GC00668K] |
| 31. Jun Sang, Kang Liu, Qun Ma, Bing Li, Cui-qin Li. (2019) Combination of a deep eutectic solvent and macroporous resin for green recovery of anthocyanins from Nitraria tangutorun Bobr. fruit. SEPARATION SCIENCE AND TECHNOLOGY, 54 (18): (3082-3090). [10.1080/01496395.2018.1559190] |
| 32. Wangen Zhao, Fengyang Yu, Shengzhong Frank Liu. (2019) Fabrication of a High-Quality Cu2ZnSn(S,Se)4 Absorber Layer via an Aqueous Solution Process and Application in Solar Cells. ACS Applied Materials & Interfaces, 11 (1): (634–639). [PMID:30560655] [10.1021/acsami.8b15354] |
| 33. Hao Ling, Sen Liu, Hongxia Gao, Zhiwu Liang. (2019) Effect of heat-stable salts on absorption/desorption performance of aqueous monoethanolamine (MEA) solution during carbon dioxide capture process. SEPARATION AND PURIFICATION TECHNOLOGY, 212 (822). [10.1016/j.seppur.2018.12.001] |
| 34. Meng Xia, Wenjie Dong, Minyan Gu, Cheng Chang, Zheng Shen, Yalei Zhang. (2018) Synergetic effects of bimetals in modified beta zeolite for lactic acid synthesis from biomass-derived carbohydrates. RSC Advances, 8 (16): (8965-8975). [PMID:35539821] [10.1039/C7RA12533J] |
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