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甘氨酰-L-酪氨酸水合物

    级别和纯度:
  • ≥98%
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货号 (SKU) 包装规格 是否现货 价格 数量
G121425-1g
1g 现货 Stock Image
G121425-5g
5g 现货 Stock Image
G121425-10g
10g 现货 Stock Image
G121425-25g
25g 现货 Stock Image
G121425-100g
100g 现货 Stock Image
G121425-500g
500g 现货 Stock Image
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多肽 (100)

基本描述

别名 甘氨酰-L-酪氨酸 | 甘氨酸-酪氨酸 | N-甘氨酰-L-酪氨酸
英文别名 Gly-Tyr | EINECS 211-525-1 | NSC 118362 | NSC-83260 | AKOS010366204 | Glycyl-L-tyrosine | GY | G-Y | GLYCYL-L-TYROSINE [USP-RS] | s10390 | GY dipeptide | G-Y Dipeptide | Oocyan | Quertine | NSC 83260 | UNII-A226496H4O | 2-Morpholin-4-yl-6-thianthren-1-ylp
规格或纯度 ≥98%
英文名称 Glycyl-L-tyrosine Hydrate
储存温度 -20°C储存
运输条件 超低温冰袋运输
纯度 ≥98%

关联靶点(人)

ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

Slc15a2 Oligopeptide transporter, kidney isoform (114 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Slc15a1 Solute carrier family 15 member 1 (124 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504756142
EC号 211-525-1
分子类型
IIUPAC Name (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid
INCHI 1S/C11H14N2O4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1
InChi Key XBGGUPMXALFZOT-VIFPVBQESA-N
Smiles C1=CC(=CC=C1CC(C(=O)O)NC(=O)CN)O
Isomeric SMILES C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CN)O
关联CAS 207300-83-2
分子量 238.24 (as Anhydrous)
Beilstein号 2700715
Reaxy-Rn 2138993
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2138993&ln=

化学和物理性质

比旋光度 47.5°
熔点 282 °C
分子量 238.240 g/mol
XLogP3 -3.300
氢键供体数Hydrogen Bond Donor Count 4
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 5
精确质量Exact Mass 238.095 Da
单同位素质量Monoisotopic Mass 238.095 Da
拓扑极表面积Topological Polar Surface Area 113.000 Ų
重原子数Heavy Atom Count 17
形式电荷Formal Charge 0
复杂度Complexity 275.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 1
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
个人防护装备 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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找到15个结果

批号(Lot Number) 证书类型 货号
I2128028 分析证书 G121425
H2420539 分析证书 G121425
H2420544 分析证书 G121425
H2420537 分析证书 G121425
H2420538 分析证书 G121425
H2406438 分析证书 G121425
F2009062 分析证书 G121425
K1511058 分析证书 G121425
H1930052 分析证书 G121425
C2219270 分析证书 G121425
C2219271 分析证书 G121425
C2219272 分析证书 G121425
C2219302 分析证书 G121425
D1823058 分析证书 G121425
D1823059 分析证书 G121425

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此产品的引用文献

引用文献

1. Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN.  (2006)  Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding..  J Med Chem,  49  (12): (3636-44).  [PMID:16759105]
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8. J D House,P B Pencharz,R O Ball.  (1997-04-01)  Tyrosine kinetics and requirements during total parenteral nutrition in the neonatal piglet: the effect of glycyl-L-tyrosine supplementation..  Pediatric research,  41  ((4 Pt 1)): (575-583).  [PMID:9098863]
9. J K Park,S J Cho,S Lee,K S Kim,D H Kim.  (1995-04-01)  Conformational energies of substrates and inhibitors for carboxypeptidase A: stereoelectronic effect..  Journal of biomolecular structure & dynamics,  12  ((5)): (1033-1040).  [PMID:7626238]
10. S Himmelseher,E Pfenninger,P Herrmann.  (1996-07-01)  Cerebrospinal and plasma amino acid concentrations after administration of i.v. glycyl-glutamine and glycyl-tyrosine containing amino acid solutions in humans..  JPEN. Journal of parenteral and enteral nutrition,  20  ((4)): (281-286).  [PMID:8865110]
11. E A Liechty,D W Boyle,H Moorehead,L Auble,S C Denne.  (1999-06-04)  Aromatic amino acids are utilized and protein synthesis is stimulated during amino acid infusion in the ovine fetus..  The Journal of nutrition,  129  ((6)): (1161-1166).  [PMID:10356081]
12. M Miyashita,R Matsunaga,Y Seyama,S Yamashita.  (1999-10-08)  [Studies on iodinated compounds. X. Isolation and purification of iodoglycyltyrosines]..  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan,  119  ((9)): (681-687).  [PMID:10511819]
13. C E Sänger-van de Griend.  (1999-12-23)  Enantiomeric separation of glycyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors..  Electrophoresis,  20  ((17)): (3417-3424).  [PMID:10608709]
14. S A Roberts,R O Ball,A M Moore,R M Filler,P B Pencharz.  (2001-01-03)  The effect of graded intake of glycyl-L-tyrosine on phenylalanine and tyrosine metabolism in parenterally fed neonates with an estimation of tyrosine requirement..  Pediatric research,  49  ((1)): (111-119).  [PMID:11134500]
15. Martin G Schmid,Maria Hölbling,Nikola Schnedlitz,Gerald Gübitz.  (2004-11-25)  Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors..  Journal of biochemical and biophysical methods,  61  ((1-2)): (1-10).  [PMID:15560917]
16. Christina Gatschelhofer,Martin G Schmid,Karin Schreiner,Thomas R Pieber,Frank M Sinner,Gerald Gübitz.  (2006-03-25)  Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP)..  Journal of biochemical and biophysical methods,  69  ((1-2)): (67-77).  [PMID:16556463]
17. Martin G Schmid,Karin Schreiner,Daniela Reisinger,Gerald Gübitz.  (2006-08-10)  Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column..  Journal of separation science,  29  ((10)): (1470-1475).  [PMID:16894792]
18. Heike Hödl,Martin G Schmid,Gerald Gübitz.  (2008-06-24)  Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids..  Journal of chromatography. A,  1204  ((2)): (210-218).  [PMID:18571185]
19. Takeharu Nakahara,Katsutoshi Sugimoto,Atsushi Sano,Hitomi Yamaguchi,Hiroshi Katayama,Riichiro Uchida.  (2012-03-16)  Antihypertensive mechanism of a peptide-enriched soy sauce-like seasoning: the active constituents and its suppressive effect on renin-angiotensin-aldosterone system..  Journal of food science,  76  ((8)): (H201-H206).  [PMID:22417592]
20. Sidsel Frølund,Louise Langthaler,Morten A Kall,René Holm,Carsten Uhd Nielsen.  (2012-08-03)  Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides..  Molecular pharmaceutics,  ((9)): (2761-2769).  [PMID:22853447]
21. Yuanzhong Yang,Reinhard I Boysen,Jamil Chowdhury,Asif Alam,Milton T W Hearn.  (2015-04-22)  Analysis of peptides and protein digests by reversed phase high performance liquid chromatography-electrospray ionisation mass spectrometry using neutral pH elution conditions..  Analytica chimica acta,  872  (84-94).  [PMID:25892073]
22. Wentao Wang,Xing Xiao,Jia Chen,Li Jia.  (2015-08-13)  Carboxyl modified magnetic nanoparticles coated open tubular column for capillary electrochromatographic separation of biomolecules..  Journal of chromatography. A,  1411  (92-100).  [PMID:26265004]
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28. Shanshan Wu,Chunchun Zhang,Ruyin Cao,Dingguo Xu,Hua Guo.  (2011-07-08)  pH-Dependent reactivity for glycyl-L-tyrosine in carboxypeptidase-A-catalyzed hydrolysis..  The journal of physical chemistry. B,  115  ((34)): (10360-10367).  [PMID:21732684]
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