甘氨酰-L-苯丙氨酸

2篇引用文献

COA

级别和纯度:

≥98%

CAS编号: 3321-03-7
分子式: C₁₁H₁₄N₂O₃
分子量: 222.24
Beilstein号: 2279318
MDL号: MFCD00065110
PubChem编号: 92953
PubChem SID: 504756153

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货号 (SKU)	包装规格	是否现货
G121421-1g	1g	现货
G121421-5g	5g	现货
G121421-25g	25g	现货

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基本描述

英文别名	G0136 \| T72314 \| (S)-2-(2-Aminoacetamido)-3-phenylpropanoicacid \| N-Glycyl-3-phenylalanine \| SCHEMBL232699 \| (S)-2-(2-Aminoacetamido)-3-phenylpropanoic acid \| (S)-2-(2-Amino-acetylamino)-3-phenyl-propionic acid \| AKOS010366203 \| CHEBI:73912 \| Glycylphenyl
规格或纯度	≥98%
英文名称	Glycyl-L-phenylalanine
储存温度	-20°C储存
运输条件	超低温冰袋运输
产品介绍	储存温度：?20°C
纯度	≥98%

关联靶点（人）

ACE Tclin Angiotensin-converting enzyme (1423 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 活性数据)

点击查看靶蛋白信息： SLC15A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A2 Tchem Solute carrier family 15 member 2 (186 活性数据)

点击查看靶蛋白信息： SLC15A2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Tpp2 Tripeptidyl aminopeptidase (141 活性数据)

点击查看靶蛋白信息： Tpp2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Slc15a2 Oligopeptide transporter, kidney isoform (114 活性数据)

点击查看靶蛋白信息： Slc15a2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Plasma (328 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Slc15a1 Solute carrier family 15 member 1 (124 活性数据)

点击查看靶蛋白信息： Slc15a1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GAP1 General amino-acid permease GAP1 (481 活性数据)

点击查看靶蛋白信息： GAP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504756153
分子类型	小分子
IIUPAC Name	(2S)-2-[(2-aminoacetyl)amino]-3-phenylpropanoic acid
INCHI	1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1
InChi Key	JBCLFWXMTIKCCB-VIFPVBQESA-N
Smiles	C1=CC=C(C=C1)CC(C(=O)O)NC(=O)CN
Isomeric SMILES	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)CN
分子量	222.24
Beilstein号	2279318
Reaxy-Rn	2124348
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2124348&ln=

化学和物理性质

敏感性	对热敏感
比旋光度	41° (C=2,H2O)
分子量	222.240 g/mol
XLogP3	-2.700
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	5
精确质量Exact Mass	222.1 Da
单同位素质量Monoisotopic Mass	222.1 Da
拓扑极表面积Topological Polar Surface Area	92.400 Å²
重原子数Heavy Atom Count	16
形式电荷Formal Charge	0
复杂度Complexity	250.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3
个人防护装备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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找到5个结果

批号(Lot Number)	证书类型	货号
K2105703	分析证书	G121421
L2431021	分析证书	G121421
K2215332	分析证书	G121421
K2215334	分析证书	G121421
K2215336	分析证书	G121421

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引用文献

1. Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN. (2006) Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.. J Med Chem, 49 (12): (3636-44). [PMID:16759105]
2. S J Reshkin,G A Ahearn. (1991-03-01) Intestinal glycyl-L-phenylalanine and L-phenylalanine transport in a euryhaline teleost.. The American journal of physiology, 260 ((3 Pt 2)): (R563-R569). [PMID:2001005]
3. B J Clark,J E Mama. (1989-01-01) Resolution of chiral compounds by HPLC using mobile phase additives and a porous graphitic carbon stationary phase.. Journal of pharmaceutical and biomedical analysis, 7 ((12)): (1883-1888). [PMID:2490578]
4. H U Demuth,A Schierhorn,P Bryan,R Höfke,H Kirschke,D Brömme. (1996-07-18) N-peptidyl, O-acyl hydroxamates: comparison of the selective inhibition of serine and cysteine proteinases.. Biochimica et biophysica acta, 1295 ((2)): (179-186). [PMID:8695644]
5. O K Argirov,I I Kerina. (1996-01-01) Interaction of glycyl-phenylalanine with carbohydrates as a model of N-terminal glycation of proteins.. Ophthalmic research, 28 Suppl 1 (62-64). [PMID:8727968]
6. J J Sperinde,B D Martens,L G Griffith. (1999-03-17) Tresyl-mediated synthesis: kinetics of competing coupling and hydrolysis reactions as a function of pH, temperature, and steric factors.. Bioconjugate chemistry, 10 ((2)): (213-220). [PMID:10077470]
7. C E Sänger-van de Griend. (1999-12-23) Enantiomeric separation of glycyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors.. Electrophoresis, 20 ((17)): (3417-3424). [PMID:10608709]
8. T Takarada,M Yashiro,M Komiyama. (2000-12-29) Catalytic hydrolysis of peptides by cerium(IV).. Chemistry (Weinheim an der Bergstrasse, Germany), 6 ((21)): (3906-3913). [PMID:11126951]
9. M Komiyama. (2001-02-24) Lanthanide ion-mediated peptide hydrolysis.. Metal ions in biological systems, 38 (25-41). [PMID:11219011]
10. Martin G Schmid,Maria Hölbling,Nikola Schnedlitz,Gerald Gübitz. (2004-11-25) Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors.. Journal of biochemical and biophysical methods, 61 ((1-2)): (1-10). [PMID:15560917]
11. Wutharath Chin,Jean-Pierre Dognon,François Piuzzi,Benjamin Tardivel,Iliana Dimicoli,Michel Mons. (2005-01-13) Intrinsic folding of small peptide chains: spectroscopic evidence for the formation of beta-turns in the gas phase.. Journal of the American Chemical Society, 127 ((2)): (707-712). [PMID:15643896]
12. Ish Kumar,R F Pratt. (2005-07-27) Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.. Biochemistry, 44 ((30)): (9961-9970). [PMID:16042373]
13. Ish Kumar,R F Pratt. (2005-07-27) Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.. Biochemistry, 44 ((30)): (9971-9979). [PMID:16042374]
14. Christina Gatschelhofer,Martin G Schmid,Karin Schreiner,Thomas R Pieber,Frank M Sinner,Gerald Gübitz. (2006-03-25) Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).. Journal of biochemical and biophysical methods, 69 ((1-2)): (67-77). [PMID:16556463]
15. Roderick Y H Lim,Ning-Ping Huang,Joachim Köser,Jie Deng,K H Aaron Lau,Kyrill Schwarz-Herion,Birthe Fahrenkrog,Ueli Aebi. (2006-06-14) Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport.. Proceedings of the National Academy of Sciences of the United States of America, 103 ((25)): (9512-9517). [PMID:16769882]
16. Martin G Schmid,Karin Schreiner,Daniela Reisinger,Gerald Gübitz. (2006-08-10) Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column.. Journal of separation science, 29 ((10)): (1470-1475). [PMID:16894792]
17. Kuniyo Inouye,Koji Nakamura,Masayuki Kusano,Kiyoshi Yasukawa. (2007-08-11) Improvement in performance of affinity gels containing Gly-D-Phe as a ligand to thermolysin due to increasing the spacer chain length.. Bioscience, biotechnology, and biochemistry, 71 ((8)): (2083-2086). [PMID:17690447]
18. Kenji Maehashi,Mami Matano,Miho Nonaka,Shigezo Udaka,Yasushi Yamamoto. (2007-09-12) Riboflavin-binding protein is a novel bitter inhibitor.. Chemical senses, 33 ((1)): (57-63). [PMID:17846099]
19. Heike Hödl,Martin G Schmid,Gerald Gübitz. (2008-06-24) Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.. Journal of chromatography. A, 1204 ((2)): (210-218). [PMID:18571185]
20. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912]
21. Alexandra Rollett,Marc Schroeder,Konstantin P Schneider,Roland Fischer,Franz Kaufmann,Rainer Schöftner,Georg M Guebitz. (2010-06-16) Covalent immobilisation of protease and laccase substrates onto siloxanes.. Chemosphere, 80 ((8)): (922-928). [PMID:20547407]
22. Diego Jose Z Delfiol,Jose P Oliveira-Filho,Fernanda L Casalecchi,Thatiane Kievitsbosch,Carlos A Hussni,Franklin Riet-Correa,João P Araujo,Alexandre S Borges. (2012-01-14) Equine poisoning by coffee husk (Coffea arabica L.).. BMC veterinary research, 8 (4-4). [PMID:22239973]
23. Sidsel Frølund,Louise Langthaler,Morten A Kall,René Holm,Carsten Uhd Nielsen. (2012-08-03) Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.. Molecular pharmaceutics, 9 ((9)): (2761-2769). [PMID:22853447]
24. S W Polly Chan,John Greaves,Nancy A Da Silva,Szu-Wen Wang. (2012-08-21) Assaying proline hydroxylation in recombinant collagen variants by liquid chromatography-mass spectrometry.. BMC biotechnology, 12 (51-51). [PMID:22901055]
25. Merrell A Johnson,Bruce D Ray,Stephen R Wassall,Horia I Petrache. (2015-02-19) Equivalent Isopropanol Concentrations of Aromatic Amino Acids Interactions with Lipid Vesicles.. The Journal of membrane biology, 248 ((4)): (695-703). [PMID:25691267]
26. Csilla Nemeth,Cai-yun Yang,Paul Kasprzak,Stella Hubbart,Duncan Scholefield,Surbhi Mehra,Emma Skipper,Ian King,Julie King. (2015-06-09) Generation of amphidiploids from hybrids of wheat and related species from the genera Aegilops, Secale, Thinopyrum, and Triticum as a source of genetic variation for wheat improvement.. Genome, 58 ((2)): (71-79). [PMID:26053312]
27. Wentao Wang,Xing Xiao,Jia Chen,Li Jia. (2015-08-13) Carboxyl modified magnetic nanoparticles coated open tubular column for capillary electrochromatographic separation of biomolecules.. Journal of chromatography. A, 1411 (92-100). [PMID:26265004]
28. Julia Dinger,Campbell Woods,Simon D Brandt,Markus R Meyer,Hans H Maurer. (2015-11-26) Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.. Toxicology letters, 241 (82-94). [PMID:26599973]
29. D J Porter,H J Bright. (1987-07-05) The cyanogenic substrate for horseradish peroxidase is a conjugated enamine.. The Journal of biological chemistry, 262 ((19)): (9154-9159). [PMID:3110155]
30. N A Duzhenkova. (1988-09-01) [Radiochemical transformation of glycyl-containing peptides].. Radiobiologiia, 28 ((5)): (579-583). [PMID:3194487]
31. F R Backwell,D Wilson,A Schweizer. (1995-10-13) Evidence for a glycyl-proline transport system in ovine enterocyte brush-border membrane vesicles.. Biochemical and biophysical research communications, 215 ((2)): (561-565). [PMID:7487992]
32. F Yamashita,K J Kim,V H Lee. (1997-02-01) Gly-L-Phe transport and metabolism across primary cultured rabbit tracheal epithelial cell monolayers.. Pharmaceutical research, 14 ((2)): (238-240). [PMID:9090716]
33. T Mizuma,S Masubuchi,S Awazu. (1997-12-24) Intestinal absorption of stable cyclic glycylphenylalanine: comparison with the linear form.. The Journal of pharmacy and pharmacology, 49 ((11)): (1067-1071). [PMID:9401939]
34. D B Shennan,F R Backwell,D T Calvert. (1999-04-27) Metabolism of aminoacyl-p-nitroanilides by rat mammary tissue.. Biochimica et biophysica acta, 1427 ((2)): (227-235). [PMID:10216239]
35. K Morimoto,Y Uehara,K Iwanaga,M Kakemi. (1999-06-22) Tracheal barrier and the permeability of hydrophilic drugs and dipeptides.. Biological & pharmaceutical bulletin, 22 ((5)): (510-514). [PMID:10375173]
36. Susan Weng Larsen,Michael Ankersen,Claus Larsen. (2004-07-22) Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 22 ((5)): (399-408). [PMID:15265509]
37. Carmelo La Rosa,Danilo Milardi,Emanuela Amato,Matteo Pappalardo,Domenico Grasso. (2005-02-01) Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly.. Archives of biochemistry and biophysics, 435 ((1)): (182-189). [PMID:15680920]
38. Bob Thong,James Pilling,Edward Ainscow,Raj Beri,John Unitt. (2010-11-23) Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity.. Journal of biomolecular screening, 16 ((1)): (36-43). [PMID:21088147]
39. Jamie M Ireland,Emil R Unanue. (2011-12-14) Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells.. The Journal of experimental medicine, 208 ((13)): (2625-2632). [PMID:22162830]
40. Omodele Ashiru,Jonathon D Howe,Terry D Butters. (2014-06-28) Nitazoxanide, an antiviral thiazolide, depletes ATP-sensitive intracellular Ca(2+) stores.. Virology, 462-463 (135-148). [PMID:24971706]
41. Lutz Franzen,Juliane Anderski,Maike Windbergs. (2015-04-02) Quantitative detection of caffeine in human skin by confocal Raman spectroscopy--A systematic in vitro validation study.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 95 ((Pt A)): (110-116). [PMID:25828208]
42. Luigi Sbano,Massimo Bonora,Saverio Marchi,Federica Baldassari,Diego L Medina,Andrea Ballabio,Carlotta Giorgi,Paolo Pinton. (2017-01-14) TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry.. Scientific reports, 7 (40797-40797). [PMID:28084445]
43. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang. (2017) Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency. JOURNAL OF CHROMATOGRAPHY A, 1509 (83). [PMID:28629939] [10.1016/j.chroma.2017.06.034]
44. Hongkai Xie, Wenhua Ji, Dahui Liu, Wei Liu, Daijie Wang, Ruimin Lv, Xiao Wang. (2015) Surface molecularly imprinted polymers with dummy templates for the separation of dencichine from Panax notoginseng. RSC Advances, 5 (60): (48885-48892). [10.1039/C5RA06749A]

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