基本描述

别名	甘氨酰谷氨酸
英文别名	EINECS 231-019-4 \| IEFJWDNGDZAYNZ-BYPYZUCNSA-N \| G0123 \| N-(Aminoacetyl)glutamic acid # \| T72896 \| 1-[4-[4-amino-7-[1-(2-hydroxyethyl)pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl]phenyl]-3-(3-fluorophenyl)urea \| 2-(2-Amino-acetylamino)-pentanedioic acid \| (S)-2
规格或纯度	≥98%
英文名称	Gly-Glu
储存温度	-20°C储存
运输条件	超低温冰袋运输
纯度	≥98%

关联靶点（人）

ACE Tclin Angiotensin-converting enzyme (1423 活性数据)

点击查看靶蛋白信息： ACE

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 活性数据)

点击查看靶蛋白信息： SLC15A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

Slc15a1 Solute carrier family 15 member 1 (124 活性数据)

点击查看靶蛋白信息： Slc15a1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GAP1 General amino-acid permease GAP1 (481 活性数据)

点击查看靶蛋白信息： GAP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504756429
分子类型	小分子
IIUPAC Name	(2S)-2-[(2-aminoacetyl)amino]pentanedioic acid
INCHI	1S/C7H12N2O5/c8-3-5(10)9-4(7(13)14)1-2-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1
InChi Key	IEFJWDNGDZAYNZ-BYPYZUCNSA-N
Smiles	C(CC(=O)O)C(C(=O)O)NC(=O)CN
Isomeric SMILES	C(CC(=O)O)[C@@H](C(=O)O)NC(=O)CN
分子量	204.18
Beilstein号	204.18
Reaxy-Rn	1728200
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728200&ln=

化学和物理性质

敏感性	对热敏感
比旋光度	-7° (C=5,H2O)
熔点	158 °C(dec.)
分子量	204.180 g/mol
XLogP3	-5.000
氢键供体数Hydrogen Bond Donor Count	4
氢键受体数Hydrogen Bond Acceptor Count	6
可旋转键计数Rotatable Bond Count	6
精确质量Exact Mass	204.075 Da
单同位素质量Monoisotopic Mass	204.075 Da
拓扑极表面积Topological Polar Surface Area	130.000 Å²
重原子数Heavy Atom Count	14
形式电荷Formal Charge	0
复杂度Complexity	240.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

WGK Germany	3

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到5个结果

批号(Lot Number)	证书类型	货号
L2205008	分析证书	G121415
L2205009	分析证书	G121415
L2205011	分析证书	G121415
L2205587	分析证书	G121415
J1421057	分析证书	G121415

引用文献

1. Vig BS, Stouch TR, Timoszyk JK, Quan Y, Wall DA, Smith RL, Faria TN. (2006) Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.. J Med Chem, 49 (12): (3636-44). [PMID:16759105]
2. L W Haynes. (1991-04-01) Beta-endorphin C-terminal dipeptide elicits calcium influx and release of arachidonic acid metabolism in cortical neurones.. Biochemical Society transactions, 19 ((2)): (149S-149S). [PMID:1889543]
3. K Brand,W Fekl,J von Hintzenstern,K Langer,P Luppa,C Schoerner. (1989-08-01) Metabolism of glutamine in lymphocytes.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (29-33). [PMID:2569663]
4. S A Adibi. (1989-08-01) Intravenous use of glutamine in peptide form: clinical applications of old and new observations.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (89-92). [PMID:2503686]
5. G B Koelle,U J Sanville,S J Wall. (1985-08-01) Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo.. Proceedings of the National Academy of Sciences of the United States of America, 82 ((15)): (5213-5217). [PMID:3860856]
6. S Himmelseher,E Pfenninger,P Herrmann. (1996-07-01) Cerebrospinal and plasma amino acid concentrations after administration of i.v. glycyl-glutamine and glycyl-tyrosine containing amino acid solutions in humans.. JPEN. Journal of parenteral and enteral nutrition, 20 ((4)): (281-286). [PMID:8865110]
7. C E Sänger-van de Griend. (1999-12-23) Enantiomeric separation of glycyl dipeptides by capillary electrophoresis with cyclodextrins as chiral selectors.. Electrophoresis, 20 ((17)): (3417-3424). [PMID:10608709]
8. Martin G Schmid,Maria Hölbling,Nikola Schnedlitz,Gerald Gübitz. (2004-11-25) Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors.. Journal of biochemical and biophysical methods, 61 ((1-2)): (1-10). [PMID:15560917]
9. Christina Gatschelhofer,Martin G Schmid,Karin Schreiner,Thomas R Pieber,Frank M Sinner,Gerald Gübitz. (2006-03-25) Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).. Journal of biochemical and biophysical methods, 69 ((1-2)): (67-77). [PMID:16556463]
10. Martin G Schmid,Karin Schreiner,Daniela Reisinger,Gerald Gübitz. (2006-08-10) Fast chiral separation by ligand-exchange HPLC using a dynamically coated monolithic column.. Journal of separation science, 29 ((10)): (1470-1475). [PMID:16894792]
11. Theresa V Nguyen,David Fleisher,David E Smith. (2007-03-24) In vivo effects of glycyl-glutamate and glycyl-sarcosine on gabapentin oral absorption in rat.. Pharmaceutical research, 24 ((8)): (1538-1543). [PMID:17380260]
12. Heike Hödl,Martin G Schmid,Gerald Gübitz. (2008-06-24) Chiral separation of amino acids and glycyl dipeptides by chiral ligand-exchange capillary electrophoresis comparing Cu(II), Co(II), Ni(II) and Zn(II) complexes of three different sugar acids.. Journal of chromatography. A, 1204 ((2)): (210-218). [PMID:18571185]
13. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912]
14. Patricio Leyton,R Antonio Zárate,Sandra Fuentes,Carolina Paipa,Juan S Gómez-Jeria,Yessica Leyton. (2011-02-01) Influence of aluminum oxide on the prebiotic thermal synthesis of Gly-Glu-(Gly-Glu)(n) polymer.. Bio Systems, 104 ((2-3)): (118-126). [PMID:21277348]
15. Zhanli Wang,Saisai Zhang,Hongwei Jin,Wei Wang,Jianxin Huo,Lishe Zhou,Yongfu Wang,Fengqin Feng,Liangren Zhang. (2011-05-31) Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation.. European journal of medicinal chemistry, 46 ((8)): (3428-3433). [PMID:21621881]
16. Hyangmi Kim,Sang-Chul Yoon,Kwang-Ho Choi,Sung-Tae Kim,Jae-Bong Lee,Dong-Sun Kim,Ho Le Han,Kyung Sook Bae,Doo-Sang Park. (2016-12-29) Lacinutrix chionocetis sp. nov., isolated from gut of a red snow crab.. Archives of microbiology, 199 ((4)): (597-603). [PMID:28028566]
17. Takayuki K Nemoto,Toshio Ono,Yuko Ohara-Nemoto. (2018-02-13) Establishment of potent and specific synthetic substrate for dipeptidyl-peptidase 7.. Analytical biochemistry, 548 (78-81). [PMID:29432753]
18. Piia Liigand,Karl Kaupmees,Anneli Kruve. (2019-03-09) Influence of the amino acid composition on the ionization efficiencies of small peptides.. Journal of mass spectrometry : JMS, 54 ((6)): (481-487). [PMID:30849787]
19. Yuko Ohara-Nemoto,Mohammad Tanvir Sarwar,Yu Shimoyama,Takeshi Kobayakawa,Takayuki K Nemoto. (2020-12-19) Preferential dipeptide incorporation of Porphyromonas gingivalis mediated by proton-dependent oligopeptide transporter (Pot).. FEMS microbiology letters, 367 ((24)): [PMID:33338236]
20. G Ollenschläger,A Simmel,E Roth. (1989-08-01) Availability of glutamine from peptides and acetylglutamine for human tumor-cell cultures.. Metabolism: clinical and experimental, 38 ((8 Suppl 1)): (40-42). [PMID:2761419]
21. K Brand,J Von Hintzenstern,K Langer,W Fekl. (1987-09-01) Pathways of glutamine and glutamate metabolism in resting and proliferating rat thymocytes: comparison between free and peptide-bound glutamine.. Journal of cellular physiology, 132 ((3)): (559-564). [PMID:2888773]
22. G B Koelle,U J Sanville,N S Thampi. (1987-10-01) Direct neurotrophic action of glycyl-L-glutamine in the maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat.. Proceedings of the National Academy of Sciences of the United States of America, 84 ((19)): (6944-6947). [PMID:3477818]
23. A Evans,M E Smith. (1997-01-01) Effect of beta-endorphin C-terminal peptides on glucose uptake in isolated skeletal muscles of the mouse.. Peptides, 18 ((1)): (165-167). [PMID:9114466]
24. D L Owen,J S Morley,D M Ensor,J B Miles. (1998-06-25) The C-terminal tetrapeptide of beta-endorphin (MPF) enhances lymphocyte proliferative responses.. Neuropeptides, 32 ((2)): (131-139). [PMID:9639251]
25. C Winckler,G Breves,M Boll,H Daniel. (1999-12-14) Characteristics of dipeptide transport in pig jejunum in vitro.. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 169 ((7)): (495-500). [PMID:10595319]
26. Marina Ioudina,Etsuro Uemura. (2004-02-11) A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide.. Experimental neurology, 184 ((2)): (923-929). [PMID:14769384]
27. Jemma Evans,Joanne Yap,Thillini Gamage,Lois Salamonsen,Evdokia Dimitriadis,Ellen Menkhorst. (2014-05-02) Galectin-7 is important for normal uterine repair following menstruation.. Molecular human reproduction, 20 ((8)): (787-798). [PMID:24782449]
28. Robert S Jansen,Sunny Mahakena,Marcel de Haas,Piet Borst,Koen van de Wetering. (2015-10-31) ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.. The Journal of biological chemistry, 290 ((51)): (30429-30440). [PMID:26515061]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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体积

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分子量

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稀释计算器

计算配制储备溶液所需的稀释度。

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体积 1 (V1)

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浓度 2 (C2)

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

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质量（小瓶）

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所需的复溶浓度

货号 (SKU)	包装规格	是否现货
G121415-100mg	100mg	现货
G121415-500mg	500mg	现货
G121415-1g	1g	现货
G121415-5g	5g	现货

甘氨酰-L-谷氨酸

库存信息

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器