| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| F656879-1ml |
1ml |
期货  |
|
| 规格或纯度 | 10mM in DMSO |
|---|---|
| 英文名称 | FASN-IN-3 |
| 生化机理 | FASN-IN-3 是一种脂肪酸合成酶（FASN）抑制剂，提取自专利 US20170119786A1，即化合物 242A。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
FASN-IN-3 is a fatty acid synthase ( FASN ) inhibitor extracted from patent US20170119786A1, compound 242A In Vitro Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 (Compound 242A), results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation. For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:FASN |
| Isomeric SMILES | CC1=CC(=C(C=C1C2=NNC(=C2C)C)C(=O)N3CC(C3)C4=CC=C(C=C4)C#N)C |
|---|---|
| PubChem CID | 72947731 |
| MeSH Entry Terms | 4-(1-(5-(3,4-dimethyl-1H-pyrazol-5-yl)-2,4-dimethylbenzoyl)azetidin-3-yl)benzonitrile;TVB 3166;TVB-3166;TVB3166 |
| 分子量 | 384.5 |
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