| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| E431516-10ml |
10ml |
现货  |
|
| 英文别名 | Derimer | Erycin | Skid Gel E | Ermycin | Erythrocin | Kesso-Mycin | erthromycin | Erythromycine | Pantoderm | Akne-Mycin | Ery-B | Sansac | Acnesol | E-Mycin (base) | Eryhexal | Iloticina | Endoeritrin | Erycinum | Mephamycin | Pantodrin | Abomacetin | E |
|---|---|
| 规格或纯度 | Moligand™, 1 mg/mL in H2O |
| 英文名称 | Erythromycin standard solution |
| 生化机理 | 作用方式：红霉素通过与细菌 70s rRNA 复合物的 50s 亚基结合，抑制转肽步骤的延伸，特别是抑制氨基酰基从 A 位点向 P 位点的转移。抗菌谱：本品对革兰氏阴性菌和革兰氏阳性菌均有效。 |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 作用类型 | 抑制剂 |
| 作用机制 | 细菌 70S 核糖体抑制剂 |
| 备注 | 注意: This Erythromycin solution is concentrated at 1 mg/mL in H 2 O and is stable in solution at 37°C for 3 days. Stock solutions should be stored at Store at 2-8°C. |
| 产品介绍 |
Chemical structure: macrolide Application Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus . This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. . |
| ALogP | 2.7 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 204-040-1 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione |
| INCHI | 1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1 |
| InChi Key | ULGZDMOVFRHVEP-RWJQBGPGSA-N |
| Smiles | CC[C@H]1OC(=O)[C@H](C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)C(OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)C(O)[C@]1(C)O |
| Isomeric SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O |
| 分子量 | 733.93 |
| Beilstein号 | 75279 |
| 比旋光度 | -74 ° (C=2, EtOH) |
|---|---|
| 熔点 | 138-140°C |
| 分子量 | 733.900 g/mol |
| XLogP3 | 2.700 |
| 氢键供体数Hydrogen Bond Donor Count | 5 |
| 氢键受体数Hydrogen Bond Acceptor Count | 14 |
| 可旋转键计数Rotatable Bond Count | 7 |
| 精确质量Exact Mass | 733.461 Da |
| 单同位素质量Monoisotopic Mass | 733.461 Da |
| 拓扑极表面积Topological Polar Surface Area | 194.000 Ų |
| 重原子数Heavy Atom Count | 51 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 1180.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 18 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07, GHS08 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H317: 可能引起皮肤过敏反应 H319: 引起严重眼睛刺激 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P272: 被污染的工作服不允许离开工作场所 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P284: 如果通风不良，请佩戴呼吸防护装置。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P342+P316: 如果出现呼吸道症状：立即寻求急救。 |
| WGK Germany | 3 |
| RTECS | KF437500 |
| Merck Index | 3681 |
| 个人防护装备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
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