| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| D655049-1ml |
1ml |
期货  |
|
| 别名 | 7,4'-二羟基黄酮 |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | 7,4'-Dihydroxyflavone |
| 生化机理 | 7,4'-二羟基黄酮（7,4'-DHF）是一种从甘草中分离出来的黄酮类化合物，它是一种 eotaxin/CCL11 抑制剂，能够持续抑制 eotaxin 的生成，并防止地塞米松（Dex）对 eotaxin 生成的副作用。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis , the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB , STAT6 and HDAC2 .7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC 50 value of 1.4 µM IC50& Target:IC50: 1.4 μM (NCI-H292 human airway epithelial cell) (7,4'-Dihydroxyflavone) |
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