This is a demo store. No orders will be fulfilled.

首页   400-620-6333
  • 登录
  • 注册
  • 英文站
切换导航
我的购物车
搜索
高级搜索
菜单
登录
设置
྾

薯蓣皂素

15篇引用文献 COA COA
有货

库存信息

关闭

库存信息

关闭

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
D101263-20mg
 20mg 现货 Stock Image
D101263-5g
 5g 现货 Stock Image
D101263-25g
 25g 现货 Stock Image
D101263-100g
 100g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
查看相关系列
JAK/STAT Signaling (508) MicroRNA (35) Non-coding RNA (34664) STAT (138) Stem Cell/Wnt (1018) 表观遗传学 (1497)
main product photo

基本描述

别名 薯蓣皂苷元,薯芋皂素
英文别名 (3beta,25R)-spirost-5-en-3-ol | AKOS015961083 | DIOSGENIN | (25R)-5-Spirosten-3A-ol | K49P2K8WLX | MFCD00016887 | DIOSGENIN [MI] | (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,16'S)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo[10.8.0.0^{2,9}.0^{4
规格或纯度 分析标准品, ≥95%
英文名称 Diosgenine
应用 薯蓣皂素是一种植物类固醇,诱导结肠癌细胞凋亡和诱导骨肉瘤细胞凋亡，细胞周期阻滞和COX活性。
运输条件 常规运输
产品介绍

易溶于汽油、乙醇，氯仿等有机溶剂，不溶于水。
纯度 ≥95%

关联靶点（人）

STAT3 Tchem Signal transducer and activator of transcription 3 (3313 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BXPC-3 (2997 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DU-145 (51482 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HL-60 (67320 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HT-29 (80576 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Huh-7 (12904 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
K562 (73714 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MKN-45 (2102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MM96L (154 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NCI-H358 (882 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NFF (353 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SW480 (6023 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
T-24 (2342 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
THP-1 (11052 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
A549 (127892 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HBL-100 (746 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HCT-116 (91556 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HepG2 (196354 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NCI-H460 (60772 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SF-268 (49410 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KM-20L2 (14967 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HeLa (62764 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SW-620 (52400 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ASPC1 (1310 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SMMC-7721 (5516 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 (448 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 (233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
UGT1A3 Tbio UDP-glucuronosyltransferase 1-3 (217 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GES1 (603 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L02 (4864 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus pneumoniae (31063 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Enterobacter cloacae (7976 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Micrococcus luteus (7463 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Neisseria gonorrhoeae (1461 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mycobacterium tuberculosis (203094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Enterococcus faecalis (29875 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Acyrthosiphon pisum (40 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mus musculus (284745 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Stenotrophomonas maltophilia (1743 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAW (181 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Vero (26788 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 208-134-3
分子类型 小分子
IIUPAC Name (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol
INCHI 1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChi Key WQLVFSAGQJTQCK-VKROHFNGSA-N
Smiles CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1
Isomeric SMILES C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1
分子量 414.62
Beilstein号 94582
Reaxy-Rn 1296718
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1296718&ln=

化学和物理性质

密度 1.13
比旋光度 -126° (C=1,CHCl3)
熔点 205°C
分子量 414.600 g/mol
XLogP3 5.700
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 414.313 Da
单同位素质量Monoisotopic Mass 414.313 Da
拓扑极表面积Topological Polar Surface Area 38.700 Ų
重原子数Heavy Atom Count 30
形式电荷Formal Charge 0
复杂度Complexity 746.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 11
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

危险声明

H413: 可能对水生生物造成长期的有害影响
预防措施声明

P273: 避免释放到环境中。

P501: 将内容物/容器处理到。。。
WGK Germany 2
Merck Index 3295
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number) 证书类型 货号
C2222029 分析证书 D101263
D1621002 分析证书 D101263
K1707054 分析证书 D101263
L2206676 分析证书 D101263
L2206645 分析证书 D101263
L2206691 分析证书 D101263

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Shen Weiyi, Shao Wentao, Wang Qihan, Wang Bo, Zhao Gang, Gu Aihua, Jiang Zhaoyan, Hu Hai.  (2023)  Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice.  JOURNAL OF BIOMEDICAL SCIENCE,  30  (1): (1-14).  [PMID:37370162] [10.1186/s12929-023-00933-3]
2. Fan Mingxuan, Tang Lingqian, Wang Yihan, Feng Lu, Zhou Hong.  (2023)  Synthesis and characterization of SO3H-functionalized silica solid acid catalyst and application for the production of diosgenin.  JOURNAL OF NANOPARTICLE RESEARCH,  25  (7): (1-15).  [10.1007/s11051-023-05785-4]
3. Mingxuan Fan, Wenxiu Jiang, Lingqian Tang, Mengqi Zhao, Qingrong Cheng, Lu Feng, Hanjun Wu, Zhiquan Pan, Hong Zhou.  (2022)  Efficient alcoholysis of total saponins in D. zingiberensis C. H. Wright with novel magnetic solid acids through a cleaner approach.  INDUSTRIAL CROPS AND PRODUCTS,  188  (115558).  [10.1016/j.indcrop.2022.115558]
4. Yu Wang, Zhi-jian Lin, Jing Huang, Meng-zhen Chu, Xue-li Ding, Wen-jing Li, Qiu-yue Mao, Bing Zhang.  (2022)  An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery.  JOURNAL OF ETHNOPHARMACOLOGY,  295  (115450).  [PMID:35688256] [10.1016/j.jep.2022.115450]
5. Tang Lingqian, Fan Mingxuan, Pan Zhiquan, Cheng Qingrong, Feng Lu, Wu Hanjun, Zhou Hong.  (2023)  Efficient Alcoholysis of Saponins from Dioscorea zingiberensis by Solid Acids Derived from Diethylenetriamine.  CATALYSIS LETTERS,  153  (4): (1096-1108).  [10.1007/s10562-022-04058-4]
6. Hui Yuan, Xuejun Yu, Wenxiu Jiang, Bowei Shen, Farong Zhang, Zhiquan Pan, Hong Zhou.  (2021)  Polymer-based solid acid catalyst for the green production of diosgenin.  JOURNAL OF APPLIED POLYMER SCIENCE,  139  (6): (51596).  [10.1002/app.51596]
7. Zheng Wan, Huiping Xia, Shiyin Guo, Chaoxi Zeng.  (2021)  Water-in-oil Pickering emulsions stabilized solely by a naturally occurring steroidal sapogenin: Diosgenin.  FOOD RESEARCH INTERNATIONAL,  147  (110573).  [PMID:34399546] [10.1016/j.foodres.2021.110573]
8. Bowei Shen, XueJun Yu, Wenxiu Jiang, Hui Yuan, Mengqi Zhao, Hong Zhou, Zhiquan Pan.  (2021)  Green Conversion of Saponins to Diosgenin in an Alcoholysis System Catalyzed by Solid Acid Derived from Phosphorus Tailings.  ACS Omega,  6  (8): (5423–5435).  [PMID:33681582] [10.1021/acsomega.0c05627]
9. Wenxiu Jiang, Xuejun Yu, Yuan Hui, Bowei Shen, Zhang Farong, Zhiquan Pan, Hong Zhou.  (2021)  Catalytic alcoholysis of saponins in D. zingiberensis C. H. Wright (Curcuma longa L) with magnetic solid acid to prepare diosgenin by response surface methodology.  INDUSTRIAL CROPS AND PRODUCTS,  161  (113197).  [10.1016/j.indcrop.2020.113197]
10. Bowei Shen, XueJun Yu, Farong Zhang, Wenxiu Jiang, Hui Yuan, Zhiquan Pan, Hong Zhou.  (2020)  Green production of diosgenin from alcoholysis of dioscorea zingiberensis C. H. wright by a magnetic solid acid.  Journal of Cleaner Production,  271  (122297).  [10.1016/j.jclepro.2020.122297]
11. Hui Yuan, Xuejun Yu, Bowei Shen, Farong Zhang, Wenxiu Jiang, Zhiquan Pan, Hong Zhou.  (2020)  Preparation of poly (styrene-co-allyl sulfonic acid) as a novel catalyst for the alcoholysis of dioscin.  POLYMERS FOR ADVANCED TECHNOLOGIES,  31  (8): (1776-1782).  [10.1002/pat.4904]
12. Zhang Farong, Shen Bowei, Jiang Wenxiu, Yuan Hui, Zhou Hong.  (2019)  Hydrolysis extraction of diosgenin from Dioscorea nipponica Makino by sulfonated magnetic solid composites.  JOURNAL OF NANOPARTICLE RESEARCH,  21  (12): (1-11).  [10.1007/s11051-019-4702-3]
13. YanXiao Zhang, XiaoNing Gao, Nan Ma, Hong Zhou, Lu Feng.  (2024)  Efficient alcoholysis of total saponins in D. zingiberensis to diosgenin using ionic liquid-grafted MOF superacids.  MATERIALS CHEMISTRY AND PHYSICS,  319  (129389).  [10.1016/j.matchemphys.2024.129389]
14. XiaoNing Gao, YanXiao Zhang, Wei Fu, Hong Zhou, Lu Feng.  (2024)  Strong Lewis acid MOF material for efficient and clean diosgenin extraction from total saponins in D. zingiberensis C. H. Wright.  Molecular Catalysis,  555  (113860).  [10.1016/j.mcat.2024.113860]
15. Qihong Zhang, Xinyu Lin, Weike Su.  (2024)  Study on the components changes of polysaccharides and saponins during nine steaming and drying of Polygonatum sibiricum.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  [PMID:38587108] [10.1002/jsfa.13516]

溶液计算器

上海阿拉丁生化科技股份有限公司
© 2016 ALADDIN-E.COM . 版权所有,未经授权禁止拷贝本站资料,如有违反,将追究法律责任

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。

上海工商 危险品化学品经营许可证（带存储）营业执照(三证合一)