| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C656745-1ml |
1ml |
期货  |
|
| 别名 | (S)-塞拉拉塞特 |
|---|---|
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | (S)-Ceralasertib |
| 生化机理 | (S)-Ceralasertib（(S)-AZD6738）提取自专利 WO2011154737A1，化合物 II 的 IC 50 为 2.578 nM。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
(S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC 50 of 2.578 nM.(S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics.(S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition . |
| 分子类型 | 小分子 |
|---|---|
| Isomeric SMILES | C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)[S@@](=N)(=O)C)C4=C5C=CNC5=NC=C4 |
| MeSH Entry Terms | 4-(4-(1-((S(R))-S-methylsulfonimidoyl)cyclopropyl)-6-((3R)-3-methyl-4-morpholinyl)-2-pyrimidinyl)-1H-pyrrolo(2,3-b)pyridine;AZD-6738;AZD6738;ceralasertib |
| 分子量 | 412.51 |
| Reaxy-Rn | 31199993 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31199993&ln= |
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