| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C608539-5mg |
5mg |
期货  |
| |
| C608539-25mg |
25mg |
期货 |
|
| 规格或纯度 | Moligand™ |
|---|---|
| 英文名称 | CHMFL-PI4K-127 |
| 作用机制 | 恶性疟原虫磷脂酰肌醇 4-激酶 beta |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 未知 |
|---|---|
| IIUPAC Name | 6'-chloro-N-methyl-5'-(phenylsulfonamido)-[3,3'-bipyridine]-5-carboxamide |
| INCHI | 1S/C18H15ClN4O3S/c1-20-18(24)14-7-12(9-21-10-14)13-8-16(17(19)22-11-13)23-27(25,26)15-5-3-2-4-6-15/h2-11,23H,1H3,(H,20,24) |
| InChi Key | IHWSJFBJORCEAK-UHFFFAOYSA-N |
| Smiles | CNC(=O)c1cncc(c1)c1cnc(c(c1)NS(=O)(=O)c1ccccc1)Cl |
| Isomeric SMILES | CNC(=O)C1=CN=CC(=C1)C2=CC(=C(N=C2)Cl)NS(=O)(=O)C3=CC=CC=C3 |
| PubChem CID | 141754964 |
| 1. Liang X, Jiang Z, Huang Z, Li F, Chen C, Hu C, Wang W, Hu Z, Liu Q, Wang B et al.. (2020) Discovery of 6'-chloro-N-methyl-5'-(phenylsulfonamido)-[3,3'-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium.. Eur J Med Chem, 188 (112012). [PMID:31911293] |
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