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羧苄青霉素 二钠盐

2篇引用文献 COA COA
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货号 (SKU) 包装规格 是否现货 价格 数量
C432748-250mg
 250mg 期货 Stock Image
C432748-1g
 1g 期货 Stock Image
C432748-5g
 5g 期货 Stock Image
C432748-10g
 10g 期货 Stock Image
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Anti-infection (2804) Antibiotic (2632) Bacterial (5911)
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基本描述

别名 α-Carboxybenzylpenicillin disodium salt 二钠盐
英文别名 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxyphenylacetyl)amino)-3,3-dimethyl-7-oxo, disodium salt, (6S-(2alpha,5alpha,6beta))- | SW220220-1 | Disodium alpha-carboxybenzylpenicillin | Disodium, Carbenicillin | N-(2-Carboxy-3,3-dimethyl-
规格或纯度 无水级, ≥89%
英文名称 Carbenicillin disodium salt
生化机理 羧青霉素抗生素，可通过灭活细菌细胞膜内表面的转肽酶来抑制细菌细胞壁合成（肽聚糖交联）。类似于氨苄青霉素。 抗菌谱：革兰氏阳性和革兰氏阴性细菌， 假单胞菌 。
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

化学结构：肽


应用

用于选择 ampr 转化的细胞，并研究青霉素敏感的转肽酶在细胞壁生物合成中的作用。


其他说明

保存于密闭容器内，置于干燥通风处。

Chemical structure: peptide


Application

Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.


Other Notes

Keep container tightly closed in a dry and well-ventilated place.
纯度 ≥89%

关联靶点（人）

FPR1 Tchem Formyl peptide receptor 1 (1372 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Slc22a20 Solute carrier family 22 member 20 (86 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 225-360-8
分子类型 小分子
IIUPAC Name disodium;(2S,5R,6R)-6-[(2-carboxylato-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
INCHI 1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1
InChi Key RTYJTGSCYUUYAL-YCAHSCEMSA-L
Smiles CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+]
Isomeric SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+]
关联CAS 4697-36-3（free basis）
分子量 422.36
Beilstein号 5722128
Reaxy-Rn 52589494
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=52589494&ln=

化学和物理性质

溶解性 水：50 毫克/毫升
闪点(℉) 400℃
闪点(℃) 400℃
沸点 738℃
熔点 >200℃
分子量 422.400 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 7
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 422.052 Da
单同位素质量Monoisotopic Mass 422.052 Da
拓扑极表面积Topological Polar Surface Area 155.000 Ų
重原子数Heavy Atom Count 28
形式电荷Formal Charge 0
复杂度Complexity 634.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 3
未定义的原子立体中心计数Undefined Atom Stereocenter Count 1
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 3

安全和危险性（GHS）

象形图 GHS07,   GHS08
信号词 危险
危险声明

H317: 可能引起皮肤过敏反应

H334: 吸入可能引起过敏或哮喘病症状或呼吸困难
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P272: 被污染的工作服不允许离开工作场所

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P284: 如果通风不良，请佩戴呼吸防护装置。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P333+P313: 如发生皮肤刺激或皮疹：求医/就诊。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P501: 将内容物/容器处理到。。。

P342+P316: 如果出现呼吸道症状：立即寻求急救。
WGK Germany 2
RTECS ON9105000
个人防护装备 dust mask type N95 (US),Eyeshields,Faceshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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此产品的引用文献

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引用文献

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