| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C431523-25g |
25g |
期货  |
| |
| C431523-100g |
100g |
期货 |
|
| 别名 | 辛可宁 单盐酸盐 二水合物 |
|---|---|
| 英文别名 | (S)-quinolin-4-yl((2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol | GNF-Pf-3189 | NCGC00262542-03 | .alpha.-Quinidine | NSC 6176 | HMS2096J18 | Prestwick3_000608 | LA40221 | (8R,9S)-Cinchonine | UNII-V43X79NZCD | 2-Quinuclidinemethanol, .alpha.-4-quinolyl-5-v |
| 规格或纯度 | ≥85% |
| 英文名称 | (+)-Cinchonine |
| 作用类型 | 抑制剂 |
| 产品介绍 |
其他说明 残留二氢金鸡宁 General Description (+)-Cinchonine, one of the alkaloids found in the barks of cinchona tree, is mainly used in the treatment of malaria. It belongs to the monoclinic crystal system and P 2 1 space group. The solubility of cinchonine can be improved by the formation of inclusion complexes with cyclodextrins. Application (+)-Cinchonine, in the presence of lithium diisopropylamide (LDA) forms a complex, which can catalyze the asymmetric conjugate addition of benzyl- and alkylphosphonates to aromatic and heteroaromatic nitroalkenes to form the corresponding adducts. Other Notes remainder dihydrocinchonine |
| 纯度 | ≥85% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 204-234-6 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol |
| INCHI | 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18+,19-/m0/s1 |
| InChi Key | KMPWYEUPVWOPIM-QAMTZSDWSA-N |
| Smiles | C=CC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O |
| Isomeric SMILES | C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](C3=CC=NC4=CC=CC=C34)O |
| 分子量 | 294.39 |
| Beilstein号 | 89689 |
| Reaxy-Rn | 89687 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=89687&ln= |
| 比旋光度 | 223 ° (C=0.5, EtOH) |
|---|---|
| 熔点 | 256-266°C |
| 分子量 | 294.400 g/mol |
| XLogP3 | 2.700 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 294.173 Da |
| 单同位素质量Monoisotopic Mass | 294.173 Da |
| 拓扑极表面积Topological Polar Surface Area | 36.400 Ų |
| 重原子数Heavy Atom Count | 22 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 412.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 4 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H302: 吞食有害 H317: 可能引起皮肤过敏反应 H332: 吸入有害 |
| WGK Germany | 3 |
| RTECS | GD3500000 |
| Merck Index | 2287 |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
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