| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C134199-10mg |
10mg |
期货  |
|
| 别名 | 2-氨基-5-(1-羟基-2-异丙基氨基乙基)苯甲腈 |
|---|---|
| 英文别名 | cimaterol | 54239-37-1 | Cimater | Cimaterolum | AB-A 663 | AC 263,780 | 2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile | ABA-663 | ZPY8VRF0GB | AC-263780 | DTXSID2045652 | AB-A 66 | AB-A-66 | Cimaterol D7 | Benzonitrile, 2-amino-5-(1-hydroxy-2-((1-methylethyl)amino)eth |
| 规格或纯度 | Moligand™, 分析标准品 |
| 英文名称 | Cimaterol |
| 应用 | An agonist of the β-AR adrenoreceptor. |
| 运输条件 | 常规运输 |
| 作用类型 | 激动剂 |
| 作用机制 | β 1-肾上腺素受体激动剂；β 2-肾上腺素受体激动剂 |
| 产品介绍 |
Cimaterol is a β-AR adrenergic agonist. AR (adrenoreceptors; adrenergic receptors) are a family of G protein-coupled proteins involved in a variety of sympathetic nervous system activities.An agonist of the β-AR adrenoreceptor. Cimaterol is a β-AR adrenergic agonist. AR (adrenoreceptors; adrenergic receptors) are a family of G protein-coupled proteins involved in a variety of sympathetic nervous system activities. |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 632-644-9 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile |
| INCHI | 1S/C12H17N3O/c1-8(2)15-7-12(16)9-3-4-11(14)10(5-9)6-13/h3-5,8,12,15-16H,7,14H2,1-2H3 |
| InChi Key | BUXRLJCGHZZYNE-UHFFFAOYSA-N |
| Smiles | CC(C)NCC(C1=CC(=C(C=C1)N)C#N)O |
| Isomeric SMILES | CC(C)NCC(C1=CC(=C(C=C1)N)C#N)O |
| 关联CAS | 54239-37-1 |
| MeSH Entry Terms | 5-(1-hydroxy-2-(isopropylamino)ethyl)anthranilonitrile;cimaterol;cimatrol;CL 263,780;CL-263,780 |
| 分子量 | 219.28 |
| Beilstein号 | 2418129 |
| Reaxy-Rn | 2418129 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2418129&ln= |
| 溶解性 | Soluble in water (partly miscible), ethanol (100 mM), DMSO (100 mM), and methanol. |
|---|---|
| 分子量 | 219.280 g/mol |
| XLogP3 | 1.700 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 4 |
| 精确质量Exact Mass | 219.137 Da |
| 单同位素质量Monoisotopic Mass | 219.137 Da |
| 拓扑极表面积Topological Polar Surface Area | 82.100 Ų |
| 重原子数Heavy Atom Count | 16 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 258.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| WGK Germany | 3 |
| RTECS | DI2457930 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| 1. Byrem TM, Beermann DH, Robinson TF. (1998) The beta-agonist cimaterol directly enhances chronic protein accretion in skeletal muscle.. J Anim Sci, 76 (4): (988-98). [PMID:9581921] |
| 2. Lanteng Wang, Jin Wang, Ang Zhang, Xin-an Huang, Hongtao Lei. (2022) Two binding epitopes modulating specificity of immunoassay for β-agonist detection: Quantitative structure–activity relationship. FOOD CHEMISTRY, 371 (131071). [PMID:34537613] [10.1016/j.foodchem.2021.131071] |
| 3. Yufeng Zhou, Haijiao Zheng, Jiutong Ma, Qiong Jia. (2017) Preparation of a polymer monolith modified with delaminated layered double hydroxides for the microextraction of β-agonists. JOURNAL OF SEPARATION SCIENCE, 40 (7): (1548-1555). [PMID:28181395] [10.1002/jssc.201601324] |
| 4. Liang Luo, Chaochao Chen, Jincheng Xiong, Yanton Pan, Qiang Li, Xiaonan Wang, Sihan Wang, Jianzhong Shen, Zhanhui Wang. (2024) Nanozyme–Enzyme Cascade Reaction-Enhanced Ratiometric Fluorescence Immunosensing Platform for Sensitive and Accurate Detection of Ractopamine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 72 (47): (26504-26513). [PMID:39537347] [10.1021/acs.jafc.4c08869] |
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