计算溶液所需的质量、体积或浓度。
This is a demo store. No orders will be fulfilled.
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C103344-250mg |
250mg |
现货 ![]() |
| |
| C103344-1g |
1g |
现货 ![]() |
| |
| C103344-5g |
5g |
现货 ![]() |
|
| 英文别名 | 9YA6SX5S4D | AC-1409 | DTXSID4022785 | C74975 | Cefradina [INN-Spanish] | Cephradine [USAN:BAN] | Tox21_113488 | Velosef | BRN 6075388 | CEFRADINE [JAN] | KBio1_000739 | SQ 11436 | SQ-11436 | NCGC00263658-01 | VELOSEF '250' | CCG-208520 | Cefradine | Ceph |
|---|---|
| 规格或纯度 | Moligand™, ≥97% |
| 英文名称 | Cephradine |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 作用类型 | 抑制剂 |
| 作用机制 | 细菌青霉素结合蛋白抑制剂 |
| 纯度 | ≥97% |
| ALogP | 0.4 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 254-137-8 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| INCHI | 1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 |
| InChi Key | RDLPVSKMFDYCOR-UEKVPHQBSA-N |
| Smiles | CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O |
| Isomeric SMILES | CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CCC=CC3)N)SC1)C(=O)O |
| 分子量 | 349.4 |
| Reaxy-Rn | 630803 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=630803&ln= |
| 密度 | 1.47 |
|---|---|
| 分子量 | 349.400 g/mol |
| XLogP3 | 0.400 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 6 |
| 可旋转键计数Rotatable Bond Count | 4 |
| 精确质量Exact Mass | 349.11 Da |
| 单同位素质量Monoisotopic Mass | 349.11 Da |
| 拓扑极表面积Topological Polar Surface Area | 138.000 Ų |
| 重原子数Heavy Atom Count | 24 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 697.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 3 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07, GHS08 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H315: 引起皮肤刺激 H317: 可能引起皮肤过敏反应 H319: 引起严重眼睛刺激 H334: 吸入可能引起过敏或哮喘病症状或呼吸困难 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P272: 被污染的工作服不允许离开工作场所 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P284: 如果通风不良,请佩戴呼吸防护装置。 P321: 特殊处理(请参阅此标签上的...)。 P302+P352: 如皮肤沾染:用水充分清洗。 P304+P340: 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。 P333+P313: 如发生皮肤刺激或皮疹:求医/就诊。 P362+P364: 脱掉沾污的衣服,清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续:寻求医疗帮助。 P332+P317: 如果出现皮肤刺激:请寻求医疗帮助。 P319: 如果你感到不适,请寻求医疗帮助。 P342+P316: 如果出现呼吸道症状:立即寻求急救。 |
| WGK Germany | 2 |
| 1. X Yang,Q Q Yang,Q Y Guo,C Y Yi,H P Mao,J X Lin,Z P Jiang,X Q Yu. (2008-05-14) Aeromonas salmonicida peritonitis after eating fish in a patient undergoing CAPD.. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 28 ((3)): (316-317). [PMID:18474929] |
| 2. James R Adams,Douglas G Bryant. (2008-05-20) Cranial osteomyelitis: a late complication of a dental infection.. The British journal of oral & maxillofacial surgery, 46 ((8)): (673-674). [PMID:18486999] |
| 3. Muhammad Harris Shoaib,Dilnawaz Shaikh,Rabia Ismail Yousuf,Baqir S Naqvi,Khursheed Hashmi. (2008-10-22) Pharmacokinetic study of cephradine in Pakistani healthy male volunteers.. Pakistan journal of pharmaceutical sciences, 21 ((4)): (400-406). [PMID:18930862] |
| 4. Shayesteh Jahanfar,Chirk-Jenn Ng,Cheong Lieng Teng. (2009-01-23) Antibiotics for mastitis in breastfeeding women.. The Cochrane database of systematic reviews, ((1)): (CD005458-CD005458). [PMID:19160255] |
| 5. David R Foster,Shiyin Yee,Barry E Bleske,Peggy L Carver,Michael J Shea,Sujatha S Menon,Chandrasekharan Ramachandran,Lynda S Welage,Gordon L Amidon. (2009-02-28) Lack of interaction between the peptidomimetic substrates captopril and cephradine.. Journal of clinical pharmacology, 49 ((3)): (360-367). [PMID:19246733] |
| 6. Sang-Jun Choi,Ju-Hee Ryu,Heon-Woo Lee,Myung-Jae Lee,Ji-Hyung Seo,Seong-Kun Tak,Kyung-Tae Lee. (2009-10-27) Rapid and simple method for determination of cephradine in human plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS): application to the bioequivalence study.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877 ((31)): (4059-4064). [PMID:19854118] |
| 7. Qi Zhong,Zhigang Huang,Wei Guo,Shengzhong Zhang,Wentong Ge. (2009-12-18) Rhinoscleroma: case report.. American journal of otolaryngology, 31 ((5)): (381-383). [PMID:20015775] |
| 8. Fen Xu,Cheng-Gong Song,Rui-Hua Wu,Li-Ni Yang,Li-Xian Sun,Zong-Bao Zhao,Zhi-Heng Zhang,Zhong Cao,Ling Zhang. (2010-01-09) [Microcalorimetric investigation of two cephalosporins on colon bacteria activity].. Yao xue xue bao = Acta pharmaceutica Sinica, 44 ((10)): (1127-1130). [PMID:20055136] |
| 9. Muxian Jiang,Lianhong Wang,Rong Ji. (2010-06-29) Biotic and abiotic degradation of four cephalosporin antibiotics in a lake surface water and sediment.. Chemosphere, 80 ((11)): (1399-1405). [PMID:20579689] |
| 10. Jianxiu Du,Hong Li. (2010-10-12) Sensitive chemiluminescence determination of thirteen cephalosporin antibiotics with luminol-copper(II) reaction.. Applied spectroscopy, 64 ((10)): (1154-1159). [PMID:20925986] |
| 11. Juan C Vazquez,Edgardo Abalos. (2011-01-21) Treatments for symptomatic urinary tract infections during pregnancy.. The Cochrane database of systematic reviews, ((1)): (CD002256-CD002256). [PMID:21249652] |
| 12. De-Qing Lei,Chang-Qin Hu,Yan-Chun Feng,Fang Feng. (2011-03-03) [Feasibility of the extended application of near infrared universal quantitative models].. Yao xue xue bao = Acta pharmaceutica Sinica, 45 ((11)): (1421-1426). [PMID:21361043] |
| 13. J Q Chen,R X Guo. (2012-02-07) Access the toxic effect of the antibiotic cefradine and its UV light degradation products on two freshwater algae.. Journal of hazardous materials, 209-210 (520-523). [PMID:22305202] |
| 14. Yan-Bin Xu,Jia-Xin Xu,Jin-Liang Chen,Lu Huang,Shao-Qi Zhou,Yan Zhou,Li-Hua Wen. (2015-07-05) Antioxidative responses of Pseudomonas fluorescens YZ2 to simultaneous exposure of Zn and Cefradine.. Ecotoxicology (London, England), 24 ((7-8)): (1788-1797). [PMID:26141733] |
| 15. Jianqiu Chen,Fengzhu Zheng,Ruixin Guo. (2015-07-16) Algal Feedback and Removal Efficiency in a Sequencing Batch Reactor Algae Process (SBAR) to Treat the Antibiotic Cefradine.. PloS one, 10 ((7)): (e0133273-e0133273). [PMID:26177093] |
| 16. Yunmei Liang,Xuzhuang Shen,Guoying Huang,Chuanqing Wang,Ying Shen,Yonghong Yang. (2008-08-12) Characteristics of Streptococcus pyogenes strains isolated from Chinese children with scarlet fever.. Acta paediatrica (Oslo, Norway : 1992), 97 ((12)): (1681-1685). [PMID:18691162] |
| 17. Zhuming Wang,Xijuan Tan,Donghua Chen,Qiaoli Yue,Zhenghua Song. (2009-04-04) Study on the binding behavior of lysozyme with cephalosporin analogues by fluorescence spectroscopy.. Journal of fluorescence, 19 ((5)): (801-808). [PMID:19343485] |
| 18. Lichuan Niu,Zhenghua Song,Xili He. (2009-08-26) A study of the chemiluminescence behavior of cephalosporins with luminol and its analytical application.. Drug metabolism letters, 3 ((3)): (144-151). [PMID:19702549] |
| 19. Chao Lu,Nan Zhang,Jinge Li,Qianqian Li. (2010-03-02) Colorimetric detection of cephradine in pharmaceutical formulations via fluorosurfactant-capped gold nanoparticles.. Talanta, 81 ((1-2)): (698-702). [PMID:20188984] |
| 20. Mu Li,Lin-Chuan Liao,You-Yi Yan,Lin Yang,Xiao-Min Liu,Jin Dai,Xiao-Na Ma,Xin Sheng,Hong Huang,Gui Su. (2010-03-17) [Analysis of multiple cephalosporins in blood and urine by HPLC].. Fa yi xue za zhi, 25 ((6)): (437-439). [PMID:20225621] |
| 21. Men-Tai Wu,Sung-Nan Pei. (2010-09-03) Development of cephradine-induced acquired factor V inhibitors: a case report.. The Annals of pharmacotherapy, 44 ((10)): (1673-1676). [PMID:20807866] |
| 22. Jimin Han,Hyojeong Lee,Yoon Su Lee,Yun-Jeong Bae,You Sook Cho,Hee-Bom Moon,Tae-Bum Kim. (2010-10-22) Cephalosporin-induced recurrent aplastic anemia.. European journal of clinical pharmacology, 67 ((3)): (317-318). [PMID:20963403] |
| 23. Zhuming Wang,Zhenghua Song,Donghua Chen. (2010-11-30) Study on the binding behavior of bovine serum albumin with cephalosporin analogues by chemiluminescence method.. Talanta, 83 ((2)): (312-319). [PMID:21111139] |
| 24. Joana Antunes,Raquel Silva,David Pacheco,Rita Travassos,Paulo Filipe. (2011-06-04) Occupational contact allergy to cephalosporins.. Dermatology online journal, 17 ((5)): (13-13). [PMID:21635835] |
| 25. Suying Feng,Wuqing Zhou,Jiechen Zhang,Peiying Jin. (2011-06-24) Analysis of 6 cases of drug-induced pemphigus.. European journal of dermatology : EJD, 21 ((5)): (696-699). [PMID:21697060] |
| 26. Shayesteh Jahanfar,Chirk Jenn Ng,Cheong Lieng Teng. (2013-03-02) Antibiotics for mastitis in breastfeeding women.. The Cochrane database of systematic reviews, 2 ((2)): (CD005458-CD005458). [PMID:23450563] |
| 27. Han Xiao,Fariborz Nasertorabi,Sei-Hyun Choi,Gye Won Han,Sean A Reed,Raymond C Stevens,Peter G Schultz. (2015-06-04) Exploring the potential impact of an expanded genetic code on protein function.. Proceedings of the National Academy of Sciences of the United States of America, 112 ((22)): (6961-6966). [PMID:26038548] |
| 28. Wenjuan Dong, Lu Wang, Rongrong Zhang, Chaochao Wen, Ren Su, Xiaojuan Gong, Wenting Liang. (2023) High luminescent N,S,P co-doped carbon dots for the fluorescence sensing of extreme acidity and folic acid. DALTON TRANSACTIONS, 52 (19): (6551-6558). [PMID:37185994] [10.1039/D3DT00560G] |
| 29. Xuan Ma, Yue Wang, Wenting Wang, Jake Heinlein, Lisa D. Pfefferle, Xuemeng Tian. (2023) Strategic preparation of porous magnetic molecularly imprinted polymers via a simple and green method for high-performance adsorption and removal of meropenem. TALANTA, 258 (124419). [PMID:36893497] [10.1016/j.talanta.2023.124419] |
| 30. Jun-Jie ZHU, Qi-Sen HUANG, Sheng-Quan LIU, Wei-Jia DING, Ya-Hong XIONG, Chun-Yuan LI. (2022) Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum. Chinese Journal of Natural Medicines, 20 (537). [PMID:35907652] [10.1016/S1875-5364(22)60171-7] |
| 31. Junjie Zhu, Ziyang Li, Haihong Lu, Shengquan Liu, Weijia Ding, Jiazhong Li, Yahong Xiong, Chunyuan Li. (2021) New diphenyl ethers from a fungus Epicoccum sorghinum L28 and their antifungal activity against phytopathogens. BIOORGANIC CHEMISTRY, 115 (105232). [PMID:34371373] [10.1016/j.bioorg.2021.105232] |
| 32. Fengli Shao, Xu Zhang, Xiantao Sun, Jingge Shang. (2021) Antibiotic removal by activated biochar: performance, isotherm, and kinetic studies. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, [10.1080/01932691.2020.1737106] |
| 33. Yanan Yan, Lin Li, Huilin Zhang, Fangfang Du, Yating Meng, Shaomin Shuang, Ruibing Wang, Shengmei Song, Chuan Dong. (2021) Carbon dots for ratiometric fluorescence detection of morin. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 256 (119751). [PMID:33819765] [10.1016/j.saa.2021.119751] |
| 34. Xueqing Guo, Yang Liu, Wenjuan Dong, Qin Hu, Yong Li, Shaomin Shuang, Chuan Dong, Lishuai Cai, Xiaojuan Gong. (2021) Azithromycin detection in cells and tablets by N,S co-doped carbon quantum dots. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 252 (119506). [PMID:33561684] [10.1016/j.saa.2021.119506] |
| 35. Guo Feng, Zhu Zihan, Zheng Zhangqin, Jin Ying, Di Xiaoxuan, Xu Zhonghao, Guan Hongwei. (2020) Facile synthesis of highly efficient fluorescent carbon dots for tetracycline detection. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 27 (4): (4520-4527). [PMID:31768961] [10.1007/s11356-019-06779-3] |
| 36. Pengcheng Xing, Di Wu, Jingshuai Chen, Jiming Song, Changjie Mao, Yuanhao Gao, Helin Niu. (2019) A Cd-MOF as a fluorescent probe for highly selective, sensitive and stable detection of antibiotics in water. ANALYST, 144 (8): (2656-2661). [PMID:30843538] [10.1039/C8AN02442A] |
| 37. Zhenbin Chen, Haohan Cai, Feng Huang, Zongping Wang, Yiqun Chen, Zizheng Liu, Pengchao Xie. (2024) Degradation of β-lactam antibiotics by Fe(III)/HSO3− system and their quantitative structure-activity relationship. ENVIRONMENTAL RESEARCH, 259 (119577). [PMID:38986801] [10.1016/j.envres.2024.119577] |
| 38. Chen De Xing, Long Yun Fei. (2024) Multifunctional Copper Nanoclusters for the Detection of pH and Berberine Hydrochloride. JOURNAL OF FLUORESCENCE, (1-11). [PMID:39576459] [10.1007/s10895-024-04033-9] |