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1-溴十七氟辛烷
有货
库存信息
| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| B423918-1ml |
1ml |
期货  |
|
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基本描述
| 别名 | 全氟溴辛烷 | 1-溴-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-十七氟辛烷 | 全氟辛基溴 | 全氟辛烷基溴 | 1-溴全氟辛烷 |
|---|---|
| 英文别名 | D05439 | FS-4333 | SR-01000944517-1 | SR-01000944517 | HY-B1724 | Imagent (TN) | PERFLUBRON [USP-RS] | SCHEMBL33826 | V08CX01 | Heptadecafluoro-n-octyl Bromide | PERFLUBRON [ORANGE BOOK] | FT-0607546 | Long's compound | N-perfluorooctyl bromide | bromure |
| 规格或纯度 | 10mM in DMSO |
| 英文名称 | 1-Bromoheptadecafluorooctane |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
1-溴十七氟辛烷是一种全氟化碳。使用精氨酸-甘氨酸-天冬氨酸 (RGD) 多肽对全氟辛基溴的聚乙二醇化聚酯纳米胶囊进行表面修饰，用于肿瘤成像。全氟辛基溴纳米胶囊已被开发作为超声和磁共振成像 (MRI) 的双重造影剂。 1-溴十七氟辛烷可作为氟-19 磁共振成像血管系统造影剂或用于合成氧载体，也被用作血液替代品乳剂中的氧载体。 1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI). Oxygen carrier in emulsions used as blood substitutes. |
关联靶点（人）
LMNA
Tbio
Prelamin-A/C
(36751 活性数据)
关联靶点（其它种属）
Hdac6
Histone deacetylase 6 (222 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
名称和识别符
| EC号 | 207-028-4 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane |
| INCHI | 1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 |
| InChi Key | WTWWXOGTJWMJHI-UHFFFAOYSA-N |
| Smiles | C(C(C(C(C(F)(F)Br)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F |
| Isomeric SMILES | C(C(C(C(C(F)(F)Br)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F |
| 分子量 | 498.96 |
| Beilstein号 | 2016022 |
| Reaxy-Rn | 2016022 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2016022&ln= |
化学和物理性质
| 敏感性 | 对光敏感 |
|---|---|
| 折光率 | 1.305 |
| 沸点 | 141°C |
| 熔点 | 6°C |
| 分子量 | 498.960 g/mol |
| XLogP3 | 6.900 |
| 氢键供体数Hydrogen Bond Donor Count | 0 |
| 氢键受体数Hydrogen Bond Acceptor Count | 17 |
| 可旋转键计数Rotatable Bond Count | 6 |
| 精确质量Exact Mass | 497.891 Da |
| 单同位素质量Monoisotopic Mass | 497.891 Da |
| 拓扑极表面积Topological Polar Surface Area | 0.000 Ų |
| 重原子数Heavy Atom Count | 26 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 527.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
安全和危险性（GHS）
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 3 |
| RTECS | RG8700000 |
| Merck Index | 7156 |
| 个人防护装备 | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
此产品的引用文献
引用文献
| 1. Yupeng Cao, Xiaohan Zhou, Xiaoli Liu, Mei Yang, Wentao Liu, Dong Han. (2023) High-Sensitivity, Low-Field 19F-MRI Approach Using High Manganese Ferrite Concentrations. ANALYTICAL CHEMISTRY, 95 (28): (10572–10579). [PMID:37403032] [10.1021/acs.analchem.3c00379] |
| 2. Xu Xiaolin, Guan Wencai, Yu Xiaolei, Xu Guoxiong, Wang Chenglong. (2023) Non-interfacial self-assembly of synthetic protocells. Biomaterials Research, 27 (1): (1-12). [PMID:37400932] [10.1186/s40824-023-00402-w] |
| 3. Liang Hong, Jianman Wang, Yi Zhou, Guofu Shang, Tao Guo, Hailong Tang, Jiangmin Li, Yali Luo, Xiangyu Zeng, Zhu Zeng, Zuquan Hu. (2023) Orthogonal Optimization, Characterization, and In Vitro Anticancer Activity Evaluation of a Hydrogen Peroxide-Responsive and Oxygen-Reserving Nanoemulsion for Hypoxic Tumor Photodynamic Therapy. Cancers, 15 (5): (1576). [PMID:36900370] [10.3390/cancers15051576] |
| 4. Liyao Zhang, Peijie Huang, Shubin Huang, Tao Wang, Shufeng Chen, Zhihao Chen, Yi Zhou, Linghao Qin. (2022) Development of ligand modified erythrocyte coated polydopamine nanomedicine to codeliver chemotherapeutic agent and oxygen for chemo-photothermal synergistic cancer therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 626 (122156). [PMID:36058410] [10.1016/j.ijpharm.2022.122156] |
| 5. Zhang Dong, You Yuanyuan, Xu Yuan, Cheng Qingqing, Xiao Zeyu, Chen Tianfeng, Shi Changzheng, Luo Liangping. (2022) Facile synthesis of near-infrared responsive on-demand oxygen releasing nanoplatform for precise MRI-guided theranostics of hypoxia-induced tumor chemoresistance and metastasis in triple negative breast cancer. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-19). [PMID:35246149] [10.1186/s12951-022-01294-z] |
| 6. Qin Bing, Jiang Mengshi, Li Xiang, Shi Yingying, Zhang Junlei, Luo Zhenyu, Luo Lihua, Lu Yichao, Liu Xu, Wang Sijie, Du Yongzhong, Qiu Yunqing, Lou Yan, You Jian. (2021) Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy. JOURNAL OF NANOBIOTECHNOLOGY, 19 (1): (1-14). [PMID:34922537] [10.1186/s12951-021-01144-4] |
| 7. Xiaoxuan Mai, Yanzhou Chang, Yuanyuan You, Lizhen He, Tianfeng Chen. (2021) Designing intelligent nano-bomb with on-demand site-specific drug burst release to synergize with high-intensity focused ultrasound cancer ablation. JOURNAL OF CONTROLLED RELEASE, 331 (270). [PMID:33010331] [10.1016/j.jconrel.2020.09.051] |
| 8. Zheng Wang, Jinsong Ding, Xiaoqian Ma, Shengjuan Luo. (2018) Selective ultrasound contrast enhancement in the tumor by nanocapsules with perfluorooctylbromide: effect of PLGA–PEG proportion. RSC Advances, 8 (32): (17958-17966). [PMID:35542111] [10.1039/C8RA01824C] |
| 9. Shengjuan Luo, Jinsong Ding, Peiqi Wang, Zheng Wang, Xiaoqian Ma, Cejun Yang, Qi Liang, Pengfei Rong, Wei Wang. (2018) Carboxyl of Poly(D,L-lactide-co-glycolide) Nanoparticles of Perfluorooctyl Bromide for Ultrasonic Imaging of Tumor. Contrast Media & Molecular Imaging, 2018 (2957459). [PMID:29568245] [10.1155/2018/2957459] |
| 10. Xichun Qin,Yeqing Zhou,Yuzhuo Wang,Ziyao Wang,Yun Wang,Jiali Chen,Lidong Zhu,Xiaoyu Quan,Zhiwei Liu,Hao Zhang,Liqun Jiang,Hongyan Dong,Zhongming Zhang. (2020-12-29) Preparation and Characterization of Protein-loaded PFC Nanoemulsions for the Treatment of Heart Diseases by Pulmonary Administration.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 158 (105690-105690). [PMID:33359617] |
| 11. Minghui Sun, Muthu Murugananthan, Zhiming Zhou, Yan Shen, Yanrong Zhang, Xiaoguang Wang. (2024) Hydrophobic covalent organic frameworks utilized Fluorocarbon/Water system for efficient hydrogen peroxide photosynthesis. CHEMICAL ENGINEERING JOURNAL, 486 (150245). [10.1016/j.cej.2024.150245] |