| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| B135944-1mg |
1mg |
现货  |
| |
| B135944-5mg |
5mg |
现货 |
|
| 别名 | 呕吐毒素 | 3a,7a,15-三羟基-12,13-环氧单端孢霉-9-烯-8-酮 |
|---|---|
| 英文别名 | (1'R,2S,2'R,3'S,7'R,9'R,10'R)-3',10'-dihydroxy-2'-(hydroxymethyl)-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0?,?]dodecan]-5'-en-4'-one | AS-75858 | Trichothec-9-en-8-one, 12,13-epoxy-3,7,15-trihydroxy-, (3-alpha,7-alpha)- | Vomitoxin | 3J6 | |
| 规格或纯度 | ≥98% |
| 英文名称 | Deoxynivalenol |
| 生化机理 | 脱氧雪腐镰刀菌烯醇(DON)通过抑制翻译过程，阻断DNA和RNA合成。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
脱氧雪腐镰刀菌烯醇是一种霉菌毒素，通常由镰刀菌属产生，经常在谷物中检测到。该化合物在高浓度下表现出免疫抑制特性，在低浓度下具有免疫刺激作用。这种霉菌毒素的其他作用包括下调参与蛋白质合成、增殖、核糖体蛋白和线粒体的基因。进一步的研究表明，脱氧雪腐镰刀菌烯醇是内质网钙释放的诱导剂。 应用： Deoxynivalenol is a mycotoxin usually produced by Fusarium species and is often detected in grains. This compound demonstrates immunosuppressive characteristics at high concentrations and immunostimulatory effects at low concentrations. Other effects of this mycotoxin include down-regulation of genes involved in protein synthesis, proliferation, ribosomal proteins, and mitochondria. Further studies show that Deoxynivalenol is an inducer of calcium release from the endoplasmic reticulum. Application： Deoxynivalenol has been used: |
| 纯度 | ≥98% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | (1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one |
| INCHI | 1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1 |
| InChi Key | LINOMUASTDIRTM-QGRHZQQGSA-N |
| Smiles | CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)O)C)CO |
| Isomeric SMILES | CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3(C[C@H]([C@H]([C@@]34CO4)O2)O)C)CO |
| 分子量 | 296.32 |
| Reaxy-Rn | 36544681 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36544681&ln= |
| 溶解性 | Soluble in methanol, chloroform, water (slightly), ethanol (9.8 - 10.2 mg/ml), and DMSO. |
|---|---|
| 敏感性 | 对湿度敏感 |
| 分子量 | 296.310 g/mol |
| XLogP3 | -0.700 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 6 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 296.126 Da |
| 单同位素质量Monoisotopic Mass | 296.126 Da |
| 拓扑极表面积Topological Polar Surface Area | 99.500 Ų |
| 重原子数Heavy Atom Count | 21 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 558.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 7 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS06 |
|---|---|
| 信号词 | 危险 |
| WGK Germany | 3 |
| RTECS | YD0167000 |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
¥17,098.90
¥12,049.90
¥1,157.90
¥1,843.90
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