Recombinant CD11b Antibody (PE)

COA

级别和纯度:

重组

已验证

ExactAb™

5 μL/test

应用:

Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG1
克隆号: P56E55
偶联: PE

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货号 (SKU)	包装规格	是否现货
Ab223990-10T	10T	现货
Ab223990-25T	25T	现货
Ab223990-100T	100T	现货

查看相关系列

点击查看靶蛋白信息: ITGAM

Accession#:P11215 (27) CD11B (23) CR3A (23) Gene ID:3684 (27) Itgam (28) PE (196)

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基本信息

产品名称	Recombinant CD11b Antibody (PE)
别名	CD11抗原样家族成员B \| 整合素alpha M \| CD11b抗体 \| ITGAM抗体 \| Anti-CD11b抗体 \| 小鼠抗人CD11b抗体
英文别名	antigen CD11b (p170) antibody \| Antigen CD11b p170 antibody \| CD11 antigen like family member B antibody \| CD11 antigen-like family member B antibody \| CD11b antibody \| CD11b/CD18 antibody \| CD49d antibody \| Cell surface glycoprotein MAC-1 subunit alpha a
规格或纯度	ExactAb™, 已验证, 重组, 5 μL/test
生化机理	Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity). May play a role in mast cell development (By similarity). Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity)
宿主种属	小鼠(Mouse)
特异性	Human CD11b
种属反应性	人(Human)
免疫原	Human monocytes
阳性对照	Flow Cytometry: Human peripheral blood monocytes
偶联	PE
Excitation(nm)	Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)	575nm
Ex/Em(nm)	Ex:565nm;Em:575nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

ITGAM Tbio 整合素α-M(Integrin alpha-M) (0 活性数据)

点击查看靶蛋白信息： ITGAM

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD11b Antibody (PE) (Ab223990)

Recombinant CD11b Antibody (PE) (Ab223990) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood cells (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD11b Antibody (PE) (Ab223990) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (PE) (Ab180308).

Flow Cytometry: Recombinant CD11b Antibody (PE) (Ab223990)

Recombinant CD11b Antibody (PE) (Ab223990) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD11b Antibody (PE) (Ab223990) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (PE) (Ab180308). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	5μl/test For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.

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批号(Lot Number)	证书类型	货号
ZJ25F0826040	分析证书	Ab223990
ZJ25F0826041	分析证书	Ab223990
ZJ25F0826042	分析证书	Ab223990

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