Recombinant CD4 Antibody (FITC)

COA

级别和纯度:

重组

已验证

ExactAb™

0.5mg/mL

Accession #: P06332

有货

库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
Ab223921-10μg	10μg	现货
Ab223921-25μg	25μg	现货
Ab223921-100μg	100μg	现货

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Accession#:P06332 (20) Cd4 (49) FITC (209) Gene ID:12504 (20)

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基本描述

产品名称	Recombinant CD4 Antibody (FITC)
别名	分化决定族抗原4 \| CD4 抗体 \| Anti-CD4抗体
英文别名	CD_antigen: CD4 \| CD4 antigen (p55) \| CD4 antigen \| CD4 molecule \| CD4 receptor \| CD4 \| CD4mut \| T-cell surface antigen T4/Leu-3 \| T-cell surface glycoprotein CD4 \| CD 4 antibody \| CD4 (L3T4) antibody \| CD4 antibody \| CD4 antigen (p55) antibody \| CD4 anti
规格或纯度	ExactAb™, 已验证, 重组, 0.5mg/mL
生化机理	Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. Post-translational modification Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts. Phosphorylated by PKC; phosphorylation plays an important role for CD4 internalization.
产品介绍	Recombinant CD4 Antibody, clone P48A42, could be used for Flow Cytometry.
偶联	FITC
Excitation(nm)	Blue Laser(488nm)
Emission(nm)	517nm
Ex/Em(nm)	Ex:498nm;Em:517nm
Accession #	P06332
来源	CHO细胞培养上清

关联靶点（人）

CD4 Tclin T 细胞表面糖蛋白 CD4(T-cell surface glycoprotein CD4) (0 活性数据)

点击查看靶蛋白信息： CD4

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

储存与运输

物理形态	液体
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	0.5mg/mL
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

图片

Flow Cytometry: Recombinant CD4 Antibody (FITC) (Ab223921)

Recombinant CD4 Antibody (FITC) (Ab223921) - Flow Cytometry
Flow cytometry analysis of CD4 expression by C57BL/6 mouse splenocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD4 Antibody (FITC) (Ab223921) at 0.3μg/test for 1 hour at 4°C. Left panel - Rat IgG (FITC) (Ab180311).

Flow Cytometry: Recombinant CD4 Antibody (FITC) (Ab223921)

Recombinant CD4 Antibody (FITC) (Ab223921) - Flow Cytometry
Flow cytometry analysis of CD4 expression by C57BL/6 mouse splenocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD4 Antibody (FITC) (Ab223921) at 0.3μg/test for 1 hour at 4°C. Blue - Rat IgG (FITC) (Ab180311). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F0927041	分析证书	Ab223921
ZJ25F0927040	分析证书	Ab223921
ZJ25F0927039	分析证书	Ab223921

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