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Recombinant IL3RA/CD123 Antibody (APC)

Recombinant IL3RA/CD123 Antibody (APC)

级别和纯度:

1 μL/test

应用:

Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG1
克隆号: P45B45
偶联: APC

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货号 (SKU)	包装规格	是否现货
Ab223905-10T	10T	现货
Ab223905-25T	25T	现货
Ab223905-100T	100T	现货

查看相关系列

点击查看靶蛋白信息: IL3RA

Accession#:P26951 (27) APC (180) Gene ID:3563 (27) IL3R (11) Il3ra (27)

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基本信息

产品名称	Recombinant IL3RA/CD123 Antibody (APC)
别名	白介素3受体α链 \| 白细胞介素3受体亚单位α \| CD123抗体 \| IL-3RA抗体
英文别名	CD123 antigen \| CD123 \| hIL3Ra \| hIL-3Ra \| IL-3 R alpha \| IL-3 receptor subunit alpha \| IL3R alpha \| IL-3R alpha \| IL-3R subunit alpha \| IL3R \| IL3RA \| IL-3Ra \| IL-3R-alpha \| IL3RAY \| IL3RX \| IL3RY \| interleukin 3 receptor, alpha (low affinity) \| interleu
规格或纯度	重组, 已验证, ExactAb™, 1 μL/test
生化机理	Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity). Post-translational modification Ubiquitinated by RNFT2 in response to IL3. Ubiquitination leads ligand-induced degradation by the proteasome. Ubiquitinated by RNF128 via 'Lys-27'-linked polyubiquitination, facilitating its degradation through the lysosomal pathway.
宿主种属	小鼠(Mouse)
特异性	Human Interleukin-3 receptor subunit alpha
种属反应性	人(Human)
免疫原	Human IL-3Rα transfected COS cells.
阳性对照	Flow Cytometry: Human peripheral blood lymphocytes
偶联	APC
Excitation(nm)	Red Laser(633nm)
Emission(nm)	660nm
Ex/Em(nm)	Ex:650nm;Em:660nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	1 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

IL3RA Tclin 白细胞介素-3 受体亚基 α(Interleukin-3 receptor subunit alpha) (0 活性数据)

点击查看靶蛋白信息： IL3RA

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant IL3RA/CD123 Antibody (APC) (Ab223905)

Recombinant IL3RA/CD123 Antibody (APC) (Ab223905) - Flow Cytometry
Flow cytometry analysis of IL3RA/CD123 expression by human peripheral blood cells (right panel) compared to an isotype control (left panel). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant IL3RA/CD123 Antibody (APC) (Ab223905) at 1 μL/test for 1 hour at 4°C. Left panel - Mouse IgG (APC) (Ab180309).

Flow Cytometry: Recombinant IL3RA/CD123 Antibody (APC) (Ab223905)

Recombinant IL3RA/CD123 Antibody (APC) (Ab223905) - Flow Cytometry
Flow cytometry analysis of IL3RA/CD123 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Recombinant IL3RA/CD123 Antibody (APC) (Ab223905) at 1 μL/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	1.0 μL/test For flow cytometric staining, the suggested use of this reagent is 1µL per million cells in 100 µL staining volume or 1 µL per 100 µL of whole blo

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F1028275	分析证书	Ab223905
ZJ25F1028274	分析证书	Ab223905
ZJ25F1028276	分析证书	Ab223905

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