E Cadherin/CD324 Rat mAb (PE-Cy5)

COA

级别和纯度:

已验证

ExactAb™

0.5 mg/mL

应用:

Flow Cytometry

宿主种属: 大鼠(Rat)
种属反应性: 小鼠(Mouse)
亚型: Rat IgG1
克隆号: DECMA-1
偶联: PE-Cy5

有货

库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
Ab216093-10μg	10μg	现货
Ab216093-25μg	25μg	现货
Ab216093-100μg	100μg	现货

查看相关系列

点击查看靶蛋白信息: CDH1

Accession#: P09803 (12) ARC-1 (11) Cdh1 (14) E-cad (11) Ecad (11) Gene ID: 12550 (12) L-CAM (11) PE-Cy5 (58) Um (11) UVO (11) 串联染料 (162)

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基本信息

产品名称	E Cadherin/CD324 Rat mAb (PE-Cy5)
别名	上皮性钙黏附蛋白抗体 \| E Cadherin/CD324抗体
英文别名	Um \| UVO \| Ecad \| ARC-1 \| E-cad \| CAD1 \| cadherin 1, E-cadherin (epithelial) \| cadherin 1, type 1, E-cadherin (epithelial) \| Cadherin-1 \| calcium-dependent adhesion protein, epithelial \| CAM 120/80 \| CD324 antigen \| CD324 \| CDH1 \| CDHE \| cell-CAM 120/80 \|
规格或纯度	ExactAb™, 已验证, 0.5 mg/mL
生化机理	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
宿主种属	大鼠(Rat)
特异性	E Cadherin/CD324
种属反应性	小鼠(Mouse)
免疫原	Mouse PCC4azal teratocarcinoma cells
阳性对照	Flow: F9 cells
偶联	PE-Cy5
Excitation(nm)	Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)	670nm
Ex/Em(nm)	Ex:565nm;Em:670nm

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein G purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	0.5 mg/mL
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

CDH1 Tbio 钙粘蛋白-1(Cadherin-1) (0 活性数据)

点击查看靶蛋白信息： CDH1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: E Cadherin/CD324 Rat mAb (PE-Cy5) (Ab216093)

E Cadherin/CD324 Rat mAb (PE-Cy5) (Ab216093) - Flow Cytometry
Flow cytometry analysis of E Cadherin/CD324 expression by F9 cells (red) compared to an isotype control (blue). Cells were stained with E Cadherin/CD324 Rat mAb (PE-Cy5) (Ab216093) at 0.3μg/test for 1 hour at 4°C. Blue - Rat IgG (PE-Cy5) (Ab190072). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.