Integrin beta 7 Rat mAb (PE-Cy7)

COA

级别和纯度:

已验证

ExactAb™

0.5 mg/mL

应用:

Flow Cytometry

宿主种属: 大鼠(Rat)
种属反应性: 人(Human), 小鼠(Mouse)
亚型: Rat IgG2a
克隆号: FIB504
偶联: PE-Cy7

有货

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货号 (SKU)	包装规格	是否现货
Ab190043-10μg	10μg	现货
Ab190043-25μg	25μg	现货
Ab190043-100μg	100μg	现货

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点击查看靶蛋白信息: ITGB7

Accession#: P26011 (7) Accession#:P26010 (10) Gene ID: 16421 (7) Gene ID:3695 (10) Itgb7 (11) Ly69 (7) PE-Cy7 (67) 串联染料 (162)

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基本信息

产品名称	Integrin beta 7 Rat mAb (PE-Cy7)
规格或纯度	ExactAb™, 已验证, 0.5 mg/mL
生化机理	Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.
宿主种属	大鼠(Rat)
特异性	Integrin beta 7
种属反应性	人(Human),小鼠(Mouse)
免疫原	TK1 cells
阳性对照	Flow: Human peripheral blood lymphocytes.
偶联	PE-Cy7
Excitation(nm)	Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)	774nm
Ex/Em(nm)	Ex:565nm;Em:774nm

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
纯化方法	Protein G purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	0.5 mg/mL
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

ITGB7 Tclin 整合素β-7(Integrin beta-7) (0 活性数据)

点击查看靶蛋白信息： ITGB7

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043)

Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043) - Flow Cytometry
Flow cytometry analysis of Integrin beta 7 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043) at 0.3μg/test for 1 hour at 4°C. Left panel - Rat IgG (PE-Cy7) (Ab190073).

Flow Cytometry: Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043)

Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043) - Flow Cytometry
Flow cytometry analysis of Integrin beta 7 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were preincubated with Human Fc Receptor Blocking Solution (H1374078). The cells were then stained with Integrin beta 7 Rat mAb (PE-Cy7) (Ab190043) at 0.3μg/test for 1 hour at 4°C. Blue - Rat IgG (PE-Cy7) (Ab190073). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	≤1.0μg/ test For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume.

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批号(Lot Number)	证书类型	货号
ZJ25F1028540	分析证书	Ab190043
ZJ25F1028539	分析证书	Ab190043
ZJ25F1028538	分析证书	Ab190043

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