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Pinatuzumab vedotin (anti-CD22), CD22 结合剂的结合剂

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human), 大鼠(Rat), 食蟹猴(Cynomolgus monkey)
  • 亚型: Human IgG1
  • 偶联: MC-VC-PAB-MMAE
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab183323-100μg
100μg 现货 Stock Image
Ab183323-1mg
1mg 现货 Stock Image
Ab183323-5mg
5mg 现货 Stock Image
Ab183323-10mg
10mg 期货 Stock Image

基本信息

产品名称 Pinatuzumab vedotin (anti-CD22), CD22 结合剂的结合剂
别名 维汀-匹那妥珠单抗 | 维汀-匹那妥珠单抗 | 皮那珠单抗维多汀(抗 CD22)
英文别名 B cell receptor CD22 precursor antibody | B lymphocyte cell adhesion molecule antibody | B-cell receptor CD22 antibody | B-lymphocyte cell adhesion molecule antibody | BL CAM antibody | BL-CAM antibody | BLCAM antibody | CD 22 antibody | CD22 antibody | C
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥90%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 CD22
种属反应性 人(Human),大鼠(Rat),食蟹猴(Cynomolgus monkey)
偶联 MC-VC-PAB-MMAE
作用类型 结合剂
作用机制 CD22 结合剂的结合剂

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 151.97 kDa
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 1313706-14-7
分子类型 抗体偶联药物

关联靶点(人)

CD22 Tclin B细胞受体CD22(B-cell receptor CD22) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150). 

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with Pinatuzumab vedotin (anti-CD22) (Ab183323). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - ELISA
Immobilized Recombinant Human Siglec-2/CD22 protein (rp169575) at 1.0 μg/mL can bind Pinatuzumab vedotin (anti-CD22) (Ab183323) with the EC50 of 73.42 ng/mL.

Pinatuzumab vedotin (anti-CD22) (Ab183323) - SEC
The purity of Pinatuzumab vedotin (anti-CD22) (Ab183323) is more than 95% verified by HPLC.

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0708979 分析证书 Ab183323
ZJ24F0708978 分析证书 Ab183323
ZJ24F0708977 分析证书 Ab183323

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