Tifcemalimab (anti-BTLA)

COA

级别和纯度:

≥95%(SDS-PAGE&SEC-HPLC)
见COA

应用:

Animal Model
ELISA
Flow Cytometry
Functional Assay

宿主种属: 人(Human)
种属反应性: 人(Human)
亚型: Human IgG4SP
偶联: Unconjugated

有货

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货号 (SKU)	包装规格	是否现货
Ab182990-100μg	100μg	现货
Ab182990-1mg	1mg	现货
Ab182990-5mg	5mg	现货
Ab182990-10mg	10mg	期货

查看相关系列

点击查看靶蛋白信息: BTLA

Accession#:Q7Z6A9 (3) Btla (11) CD272 (5) Gene ID:151888 (3)

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基本信息

产品名称	Tifcemalimab (anti-BTLA)
别名	抗BTLA单抗 \| 4-1BB药靶抗体
英文别名	B and T lymphocyte attenuator antibody \| B and T lymphocyte associated protein antibody \| B and T lymphocyte associated antibody \| B- and T-lymphocyte attenuator antibody \| B- and T-lymphocyte-associated protein antibody \| JS004 \| MGC129743 \| BTLA antibod
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
生化机理	Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. Post-translational: Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11. N-glycosylated.
宿主种属	人(Human)
特异性	BTLA
种属反应性	人(Human)
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG4SP
轻链亚型	kappa
SDS-PAGE	146 kDa
纯化方法	Protein A purified
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

BTLA Tbio B 和 T 淋巴细胞衰减因子(B- and T-lymphocyte attenuator) (0 活性数据)

点击查看靶蛋白信息： BTLA

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Tifcemalimab (anti-BTLA) (Ab182990)

Tifcemalimab (anti-BTLA) (Ab182990) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA with Tifcemalimab (anti-BTLA) (Ab182990) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Tifcemalimab (anti-BTLA) (Ab182990)

Tifcemalimab (anti-BTLA) (Ab182990) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling BTLA (red) with Tifcemalimab (anti-BTLA) (Ab182990) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Tifcemalimab (anti-BTLA) (Ab182990)

Tifcemalimab (anti-BTLA) (Ab182990) - ELISA
Immobilized Recombinant Human BTLA protein (rp143904) at 1.0 μg/mL can bind Tifcemalimab (anti-BTLA) (Ab182990) with the EC₅₀ of 130.30 ng/mL.