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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab179373-100μg |
100μg |
现货 ![]() |
| |
| Ab179373-1mg |
1mg |
现货 ![]() |
| |
| Ab179373-5mg |
5mg |
现货 ![]() |
| |
| Ab179373-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Anrukinzumab (anti-IL-13), 白细胞介素-13 抑制剂 |
|---|---|
| 别名 | 安芦组单抗 | 安鲁金珠单抗(抗 IL-13) |
| 英文别名 | Allergic rhinitis antibody | ALRH antibody | BHR 1 antibody | BHR1 antibody | Bronchial hyperresponsiveness 1 (bronchial asthma) antibody | IL 13 antibody | IL-13 antibody | Il13 antibody | IL13_HUMAN antibody | Interleukin 13 antibody | Interleukin-13 an |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | IL13 |
| 种属反应性 | 人(Human),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 作用类型 | 抑制剂 |
| 作用机制 | 白细胞介素-13 抑制剂 |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 145.38 kDa |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 910649-32-0 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Anrukinzumab (anti-IL-13) (Ab179373) - ELISA
Immobilized Recombinant Human IL-13 Protein (rp147396) at 2.0 μg/mL can bind Anrukinzumab (anti-IL-13) (Ab179373) with the EC50 of 357.7 ng/mL.
Anrukinzumab (anti-IL-13) (Ab179373) - SEC
The purity of Anrukinzumab (anti-IL-13) (Ab179373) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab179373 | |
| 分析证书 | Ab179373 | |
| 分析证书 | Ab179373 |
¥669.90
¥479.90
¥669.90
¥669.90
¥669.90
¥669.90
¥1,099.90
¥669.90
¥463.92
| 1. Morgan, J G JG, Dolganov, G M GM, Robbins, S E SE, Hinton, L M LM and Lovett, M M.. (1992) The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.. Nucleic acids research, (11): [PMID:1408833] |
| 2. Smirnov, D V DV, Smirnova, M G MG, Korobko, V G VG and Frolova, E I EI.. (1995) Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization.. Gene, (3): [PMID:7721105] |
| 3. Defrance, T T and 6 more authors.. (1994) Interleukin 13 is a B cell stimulating factor.. The Journal of experimental medicine, (1): [PMID:7903680] |
| 4. Minty, A A and 9 more authors.. (1993) Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.. Nature, (18): [PMID:8096327] |
| 5. McKenzie, A N AN and 9 more authors.. (1993) Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:8097324] |
| 6. Dolganov, G G and 8 more authors.. (1996) Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31.. Blood, (15): [PMID:8605348] |
| 7. Miloux, B B and 6 more authors.. (1997) Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex.. FEBS letters, (20): [PMID:9013879] |
| 8. Heinzmann, A A and 31 more authors.. (2000) Genetic variants of IL-13 signalling and human asthma and atopy.. Human molecular genetics, (1): [PMID:10699178] |
| 9. Moy, F J FJ, Diblasio, E E, Wilhelm, J J and Powers, R R.. (2001) Solution structure of human IL-13 and implication for receptor binding.. Journal of molecular biology, (29): [PMID:11419948] |
| 10. Howard, T D TD and 8 more authors.. (2001) Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population.. American journal of respiratory cell and molecular biology, [PMID:11588017] |
| 11. Wang, Min M and 7 more authors.. (2003) A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis.. Human genetics, [PMID:12928861] |
| 12. Lupardus, Patrick J PJ, Birnbaum, Michael E ME and Garcia, K Christopher KC.. (2010) Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2.. Structure (London, England : 1993), (10): [PMID:20223216] |
| 13. Kasaian, Marion T MT and 6 more authors.. (2011) IL-13 antibodies influence IL-13 clearance in humans by modulating scavenger activity of IL-13Rα2.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:21622864] |