计算溶液所需的质量、体积或浓度。
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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab177900-100μg |
100μg |
现货 ![]() |
| |
| Ab177900-1mg |
1mg |
现货 ![]() |
| |
| Ab177900-5mg |
5mg |
现货 ![]() |
| |
| Ab177900-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Ensituximab (anti-MUC5AC), 其他 Mucin-5AC 的 OTHER |
|---|---|
| 别名 | 恩妥昔单抗(抗 MUC5AC) |
| 英文别名 | Gastric mucin | Major airway glycoprotein | MUC-5AC | Mucin-5 subtype AC, tracheobronchial | TBM | Tracheobronchial mucin |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | MUC5AC |
| 种属反应性 | 人(Human),恒河猴(Rhesus monkey),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 作用类型 | 其它 |
| 作用机制 | 其他 Mucin-5AC 的 OTHER |
| 克隆类型 | 重组抗体 |
|---|---|
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.5kDa (Light Chain) & 50.5 kDa (Heavy Chain), under reducing conditions; 188.1kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 1092658-06-4 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Ensituximab (anti-MUC5AC) (Ab177900) - SEC
The purity of Ensituximab (anti-MUC5AC) (Ab177900) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab177900 | |
| 分析证书 | Ab177900 | |
| 分析证书 | Ab177900 | |
| 分析证书 | Ab177900 | |
| 分析证书 | Ab177900 | |
| 分析证书 | Ab177900 |
| 1. Meezaman, D D and 5 more authors.. (1994) Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).. The Journal of biological chemistry, (29): [PMID:7513696] |
| 2. Lesuffleur, T T and 7 more authors.. (1995) Characterization of a mucin cDNA clone isolated from HT-29 mucus-secreting cells. The 3' end of MUC5AC?. The Journal of biological chemistry, (9): [PMID:7775418] |
| 3. Klomp, L W LW, Van Rens, L L and Strous, G J GJ.. (1995) Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains.. The Biochemical journal, (15): [PMID:8948439] |
| 4. Li, D D, Gallup, M M, Fan, N N, Szymkowski, D E DE and Basbaum, C B CB.. (1998) Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts.. The Journal of biological chemistry, (20): [PMID:9506983] |
| 5. Buisine, M P MP and 5 more authors.. (1998) Genomic organization of the 3'-region of the human MUC5AC mucin gene: additional evidence for a common ancestral gene for the 11p15.5 mucin gene family.. The Biochemical journal, (15): [PMID:9620876] |
| 6. Silverman, H S HS and 10 more authors.. (2001) In vivo glycosylation of mucin tandem repeats.. Glycobiology, [PMID:11445551] |
| 7. Escande, F F, Aubert, J P JP, Porchet, N N and Buisine, M P MP.. (2001) Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region.. The Biochemical journal, (15): [PMID:11535137] |
| 8. Van de Bovenkamp, Jeroen H B JH and 6 more authors.. (2003) The MUC5AC glycoprotein is the primary receptor for Helicobacter pylori in the human stomach.. Helicobacter, [PMID:14535999] |
| 9. Lidell, Martin E ME and Hansson, Gunnar C GC.. (2006) Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin.. The Biochemical journal, (1): [PMID:16787389] |
| 10. Raman, Jayalakshmi J, Guan, Yu Y, Perrine, Cynthia L CL, Gerken, Thomas A TA and Tabak, Lawrence A LA.. (2012) UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree.. Glycobiology, [PMID:22186971] |
| 11. Lira-Navarrete, Erandi and 14 more authors.. (2015) Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.. Nature communications, (5): [PMID:25939779] |
| 12. Simões, Filipa B and 7 more authors.. (2019) TMEM16A chloride channel does not drive mucus production.. Life science alliance, [PMID:31732694] |