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Lilotomab (anti-TSPAN26)

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab175580-100μg
100μg 现货 Stock Image
Ab175580-1mg
1mg 现货 Stock Image
Ab175580-5mg
5mg 现货 Stock Image
Ab175580-10mg
10mg 期货 Stock Image

基本信息

产品名称 Lilotomab (anti-TSPAN26)
别名 利洛托单抗 | 利洛托单抗(抗TSPAN26)
英文别名 CD 37 antibody | CD37 antibody | CD37 antigen antibody | CD37 molecule antibody | CD37_HUMAN antibody | Cell differentiation antigen 37 antibody | GP52 40 antibody | Leukocyte antigen CD37 antibody | Leukocyte surface antigen CD37 antibody | MGC120234 ant
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 CD37
种属反应性 人(Human)
偶联 Unconjugated

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 26.5 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 192.1 kDa, under non-reducing conditions.
纯化方法 Protein A purified
物理外观 Liquid
储存缓冲液 Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 1453362-55-4
分子类型 抗体

关联靶点(人)

CD37 Tbio 白细胞抗原 CD37(Leukocyte antigen CD37) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

Lilotomab (anti-TSPAN26) (Ab175580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling TSPAN26 with Lilotomab (anti-TSPAN26) (Ab175580) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Lilotomab (anti-TSPAN26) (Ab175580) - SEC
The purity of Lilotomab (anti-TSPAN26) (Ab175580) is more than 95% verified by HPLC.

Lilotomab (anti-TSPAN26) (Ab175580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling TSPAN26 (red) with Lilotomab (anti-TSPAN26) (Ab175580) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Lilotomab (anti-TSPAN26) (Ab175580) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling TSPAN26 (red) with Lilotomab (anti-TSPAN26) (Ab175580). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

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找到6个结果

批号(Lot Number) 证书类型 货号
ZJ24F1114099 分析证书 Ab175580
ZJ24F1114098 分析证书 Ab175580
ZJ24F1114097 分析证书 Ab175580
ZJ24F0606883 分析证书 Ab175580
ZJ24F0606882 分析证书 Ab175580
ZJ24F0606881 分析证书 Ab175580

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引用文献

1. Dahle J, Repetto-Llamazares AH, Mollatt CS, Melhus KB, Bruland OS, Kolstad A, Larsen RH.  (2013)  Evaluating antigen targeting and anti-tumor activity of a new anti-CD37 radioimmunoconjugate against non-Hodgkin's lymphoma..  Anticancer Res,  33  (1): (85-95).  [PMID:23267131]
2. Stokke C, Blakkisrud J, Løndalen A, Dahle J, Martinsen ACT, Holte H, Kolstad A.  (2018)  Pre-dosing with lilotomab prior to therapy with 177Lu-lilotomab satetraxetan significantly increases the ratio of tumor to red marrow absorbed dose in non-Hodgkin lymphoma patients..  Eur J Nucl Med Mol Imaging,  45  (7): (1233-1241).  [PMID:29470615]

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