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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab170584-100μg |
100μg |
现货 ![]() |
| |
| Ab170584-1mg |
1mg |
现货 ![]() |
| |
| Ab170584-5mg |
5mg |
现货 ![]() |
| |
| Ab170584-10mg |
10mg |
期货 ![]() |
|
| 产品名称 | Sofituzumab (anti-MUC16) |
|---|---|
| 别名 | 索非妥珠单抗 | 索菲珠单抗(抗 MUC16) |
| 英文别名 | MMUC 1206A | Sofituzumab | CA 125 antibody | CA-125 antibody | CA125 antibody | CA125 ovarian cancer antigen antibody | Cancer antigen 125 antibody | FLJ14303 antibody | MUC 16 antibody | MUC-16 antibody | MUC16 antibody | MUC16_HUMAN antibody | Mucin 16 |
| 规格或纯度 | 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA |
| 宿主种属 | 人(Human) |
| 特异性 | MUC16 |
| 应用 | ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt |
| 种属反应性 | 人(Human),大鼠(Rat),食蟹猴(Cynomolgus monkey) |
| 偶联 | Unconjugated |
| 抗体类型 | Primary antibody |
|---|---|
| 克隆类型 | 重组抗体 |
| Format | Whole IgG |
| 亚型 | Human IgG1 |
| 轻链亚型 | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 52.1 kDa (Heavy Chain), under reducing conditions; 180.9 kDa, under non-reducing conditions. |
| 纯化方法 | Protein A purified |
| 纯度 | >95% |
| 来源 | CHO supernatant |
| 物理外观 | Liquid |
| 储存缓冲液 | Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | -80℃储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。 |
| CAS编号和信息 | 1615692-28-8 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
Sofituzumab (anti-MUC16) (Ab170584) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling MUC16 (red) with Sofituzumab (anti-MUC16) (Ab170584). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Sofituzumab (anti-MUC16) (Ab170584) - SEC
The purity of Sofituzumab (anti-MUC16) (Ab170584) is more than 95% verified by HPLC.
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab170584 | |
| 分析证书 | Ab170584 | |
| 分析证书 | Ab170584 | |
| 分析证书 | Ab170584 | |
| 分析证书 | Ab170584 | |
| 分析证书 | Ab170584 |
¥799.92
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| 1. Yin, B W BW and Lloyd, K O KO.. (2001) Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16.. The Journal of biological chemistry, (20): [PMID:11369781] |
| 2. O'Brien, T J TJ and 5 more authors.. The CA 125 gene: an extracellular superstructure dominated by repeat sequences.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:11786729] |
| 3. O'Brien, Timothy J TJ, Beard, John B JB, Underwood, Lowell J LJ and Shigemasa, Kazushi K.. The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure.. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, [PMID:12218296] |
| 4. Kui Wong, Nyet N and 9 more authors.. (2003) Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125.. The Journal of biological chemistry, (1): [PMID:12734200] |
| 5. Rump, Armin A and 6 more authors.. (2004) Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.. The Journal of biological chemistry, (5): [PMID:14676194] |
| 6. McLemore, Monica R MR and Aouizerat, Bradley B.. (2005) Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer.. Biological research for nursing, [PMID:15788735] |
| 7. Argüeso, Pablo P, Tisdale, Ann A, Spurr-Michaud, Sandra S, Sumiyoshi, Mika M and Gipson, Ilene K IK.. (2006) Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye.. Investigative ophthalmology & visual science, [PMID:16384952] |