TBP Mouse mAb

COA

级别和纯度:

≥95%(SDS-PAGE)
1.0 mg/mL

应用:

ELISA
WB

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human), 大鼠(Rat), 小鼠(Mouse)
亚型: Mouse IgG2b
克隆号: AB02/2F6
偶联: Unconjugated

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货号 (SKU)	包装规格	是否现货
Ab156573-10μl	10μl	现货
Ab156573-50μl	50μL	现货
Ab156573-100μl	100μL	现货
Ab156573-1ml	1ml	期货

查看相关系列

点击查看靶蛋白信息: TBP

Accession#:P20226 (4) Gene ID:6908 (4) TBP (4)

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基本信息

产品名称	TBP Mouse mAb
别名	TATA结合蛋白 \| TATA框结合蛋白 \| TBP抗体 \| 小鼠抗人TBP单克隆抗体
英文别名	GTF2D antibody \| GTF2D1 antibody \| HDL4 antibody \| MGC117320 antibody \| MGC126054 antibody \| MGC126055 antibody \| SCA17 antibody \| TATA binding factor antibody \| TATA box factor antibody \| TATA sequence binding protein antibody \| TATA sequence-binding pro
规格或纯度	ExactAb™, 已验证, 无载体, 无叠氮钠, 高性能, ≥95%(SDS-PAGE), 1.0 mg/mL
生化机理	The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TBP forms the TFIID-A module together with TAF3 and TAF5. TBP is a general transcription factor that functions at the core of the TFIID complex. During assembly of the core PIC on the promoter, as part of TFIID, TBP binds to and also bends promoter DNA, irrespective of whether the promoter contains a TATA box. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promote. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
宿主种属	小鼠(Mouse)
特异性	Human TATA binding protein
种属反应性	人(Human),大鼠(Rat),小鼠(Mouse)
免疫原	Recombinant full length protein corresponding to human TATA binding protein
阳性对照	WB: HEK293, MCF-7, Jurkat, K562, HeLa, NIH/3T3 and C6 whole cell lysates
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150.0 KDa
纯化方法	Protein A purified
储存缓冲液	PBS, pH 7.4
浓度	1.0 mg/mL
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
分子类型	抗体

关联靶点（人）

TBP Tbio TATA盒结合蛋白(TATA-box-binding protein) (0 活性数据)

点击查看靶蛋白信息： TBP

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Western Blot: TATA binding protein Mouse mAb (Ab156573)

TATA binding protein Mouse mAb (Ab156573) - Western Blot
All lanes: TATA binding protein Mouse mAb (Ab156573) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution

Predicted band size: 38 kDa
Observed band size: 45 kDa
Exposure time: 60.0 s

Western Blot: TATA binding protein Mouse mAb (Ab156573)

应用

应用名称	稀释比例
WB	1/1000 - 1/2000

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批号(Lot Number)	证书类型	货号
ZJ25F0927970	分析证书	Ab156573
ZJ25F0927969	分析证书	Ab156573
ZJ25F0927971	分析证书	Ab156573

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