| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A655705-1ml |
1ml |
期货  |
|
| 规格或纯度 | 10mM in DMSO |
|---|---|
| 英文名称 | AZD1940 |
| 生化机理 | AZD1940 是一种口服活性高亲和力大麻素 CB1/CB2 受体激动剂，对人类 CB1R 和 CB2R 的 pK i 值分别为 7.93 和 9.06。AZD1940 具有很强的镇痛作用。 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action In Vitro AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species . MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain. For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:hCB1-R 7.93 (pKi) hCB2-R 9.06 (pKi) |
| 分子类型 | 未知 |
|---|---|
| Isomeric SMILES | CCS(=O)(=O)NC1=CC2=C(C=C1)N(C(=N2)C(C)(C)C)CC3CCC(CC3)(F)F |
| 关联CAS | 881413-29-2 |
| PubChem CID | 11675994 |
| MeSH Entry Terms | AZD1940;N-(2-tert-butyl-1-((4,4-difluorocyclohexyl)methyl)-1H-benzo(d)imidazol-5-yl)ethanesulfonamide |
| 分子量 | 413.52 |
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