| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A651241-1mg |
1mg |
期货  |
| |
| A651241-5mg |
5mg |
期货 |
|
| 别名 | 橙花酰胺醋酸盐 |
|---|---|
| 英文别名 | AKOS040760046 | Tifentai | Benzenepropanamide, N-[(1S)-1-[(acetyloxy)methyl]-2-phenylethyl]-alpha-(benzoylamino)-, (alphaS)- | MS-28013 | SCHEMBL4357298 | 2Z6NA534YE | C27H28N2O4 | Aurantiamide acetate | Asperglaucide | HY-N2905 | N-Benzoylphenylalanylphe |
| 规格或纯度 | ≥99% |
| 英文名称 | Aurantiamide acetate |
| 生化机理 | 醋酸金盏花酰胺（TMC-58A）是从马齿苋中分离出来的一种具有选择性和口服活性的胰蛋白酶抑制剂。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 产品介绍 |
Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases In Vitro Aurantiamide acetate inhibits cathepsin L (3.4.22.15) and cathepsin B (3.4.22.1) with IC 50 of 12 μM and 49 μM, respectiveiy. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:cathepsin L |
| 纯度 | ≥99% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | [(2S)-2-[[(2S)-2-benzamido-3-phenylpropanoyl]amino]-3-phenylpropyl] acetate |
| INCHI | 1S/C27H28N2O4/c1-20(30)33-19-24(17-21-11-5-2-6-12-21)28-27(32)25(18-22-13-7-3-8-14-22)29-26(31)23-15-9-4-10-16-23/h2-16,24-25H,17-19H2,1H3,(H,28,32)(H,29,31)/t24-,25-/m0/s1 |
| InChi Key | VZPAURMDJZOGHU-DQEYMECFSA-N |
| Smiles | CC(=O)OCC(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3 |
| Isomeric SMILES | CC(=O)OC[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3 |
| PubChem CID | 10026486 |
| 分子量 | 444.52 |
| 溶解性 | DMSO : 50 mg/mL (112.48 mM; Need ultrasonic) |
|---|---|
| 分子量 | 444.500 g/mol |
| XLogP3 | 4.400 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 11 |
| 精确质量Exact Mass | 444.205 Da |
| 单同位素质量Monoisotopic Mass | 444.205 Da |
| 拓扑极表面积Topological Polar Surface Area | 84.500 Ų |
| 重原子数Heavy Atom Count | 33 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 620.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
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