| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A646279-5mg |
5mg |
期货  |
| |
| A646279-10mg |
10mg |
期货 |
|
| 别名 | 阿斯匹芬那酯 |
|---|---|
| 英文别名 | 2H4MD59YVT | anabellamide | L-PHENYLALANINE, N-BENZOYL-, 2-(BENZOYLAMINO)-3-PHENYLPROPYL ESTER, (S)- | N-BENZOYL-L-PHENYLALANINOL N-BENZOYL-L-PHENYLALANINATE | NCGC00170024-01 | NSC-306231 | L-PHENYLALANINE, N-BENZOYL-, (2S)-2-(BENZOYLAMINO)-3-PHENYLPROPY |
| 规格或纯度 | ≥98% |
| 英文名称 | Asperphenamate |
| 生化机理 | Asperphenamate 是一种具有抗癌作用的花曲霉真菌代谢产物，在 T47D、MDA-MB-231 和 HL-60 细胞中的 IC 50 值分别为 92.3 μM、96.5 μM 和 97.9 μM。 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 激活剂 |
| 产品介绍 |
Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC 50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively. In Vitro Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
| 纯度 | ≥98% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| 分子类型 | 小分子 |
|---|---|
| IIUPAC Name | [(2S)-2-benzamido-3-phenylpropyl] (2S)-2-benzamido-3-phenylpropanoate |
| INCHI | 1S/C32H30N2O4/c35-30(26-17-9-3-10-18-26)33-28(21-24-13-5-1-6-14-24)23-38-32(37)29(22-25-15-7-2-8-16-25)34-31(36)27-19-11-4-12-20-27/h1-20,28-29H,21-23H2,(H,33,35)(H,34,36)/t28-,29-/m0/s1 |
| InChi Key | CVULDJMCSSACEO-VMPREFPWSA-N |
| Smiles | C1=CC=C(C=C1)CC(COC(=O)C(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3)NC(=O)C4=CC=CC=C4 |
| Isomeric SMILES | C1=CC=C(C=C1)C[C@@H](COC(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3)NC(=O)C4=CC=CC=C4 |
| PubChem CID | 173952 |
| 分子量 | 506.59 |
| 溶解性 | DMSO : 100 mg/mL (197.40 mM; Need ultrasonic) |
|---|---|
| 分子量 | 506.600 g/mol |
| XLogP3 | 6.100 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 12 |
| 精确质量Exact Mass | 506.221 Da |
| 单同位素质量Monoisotopic Mass | 506.221 Da |
| 拓扑极表面积Topological Polar Surface Area | 84.500 Ų |
| 重原子数Heavy Atom Count | 38 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 732.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
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