| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A424427-1ml |
1ml |
现货  |
|
| 别名 | 莨菪碱 | 阿托品 | 阿托品 |
|---|---|
| 英文别名 | (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate | alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester | Atropine, >=95.0% (NT) | InChI=1/C11H8Cl2N2O/c12-8-1-2-9(10(13)5-8)11(16)6-15-4-3-14-7-15 |
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Atropine |
| 生化机理 | 位于中枢和外周毒蕈碱型乙酰胆碱受体处的竞争性非选择性拮抗剂。强效，竞争性，非选择性mAChR拮抗剂（IC 50 = 2.5 nM）。引起瞳孔散大。在体内显示抗毒蕈碱和抗胆碱能作用。口服具有活性 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 拮抗剂 |
| 作用机制 | 肌卡因乙酰胆碱受体 M2 拮抗剂 |
| 产品介绍 |
Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery. |
| ALogP | 1.8 |
|---|
| EC号 | 200-104-8 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate |
| INCHI | 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16? |
| InChi Key | RKUNBYITZUJHSG-PJPHBNEVSA-N |
| Smiles | CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3 |
| Isomeric SMILES | CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3 |
| 分子量 | 289.37 |
| Beilstein号 | 91260 |
| Reaxy-Rn | 91256 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=91256&ln= |
| 敏感性 | 对光线和空气敏感 |
|---|---|
| 分子量 | 289.400 g/mol |
| XLogP3 | 1.800 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 5 |
| 精确质量Exact Mass | 289.168 Da |
| 单同位素质量Monoisotopic Mass | 289.168 Da |
| 拓扑极表面积Topological Polar Surface Area | 49.800 Ų |
| 重原子数Heavy Atom Count | 21 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 353.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 2 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 1 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS06 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H300+H330: 吞咽或吸入会致命 |
| 预防措施声明 |
P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。 P264: 处理后要彻底洗手。 P284: 如果通风不良，请佩戴呼吸防护装置。 P310: 立即致电解毒中心或医生。 P301+P310: 如误吞咽：立即呼叫急救中心/医生。 |
| WGK Germany | 3 |
| RTECS | CK0700000 |
| 个人防护装备 | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
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