| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A424359-1ml |
1ml |
现货  |
|
| 英文别名 | 5,8,11,14-Eicosatetraenoic acid | C00219 | (5Z,8Z,11Z,14Z)-Icosatetraenoic acid | A0781 | Immunocytophyte | 5,8,11,14-Eicosatetraenoate | ARACHIDONIC ACID [INCI] | all-cis-eicosa-5,8,11,14-tetraenoic acid | HMS3402M21 | s6185 | UNII-27YG812J1I | [(2S,3aR, |
|---|---|
| 规格或纯度 | Moligand™, 10mM in DMSO |
| 英文名称 | Arachidonic acid(AA) |
| 生化机理 | 类花生酸生产中的主要前体和重要的细胞信号传导介质。PLA 2从磷脂中释放出的内源性游离脂肪酸。通过COX，脂氧合酶和细胞色素p450代谢形成多种类花生酸 |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 抑制剂 |
| 作用机制 | ClC-2 的激活剂;K 2P10.1 的激活剂;K 2P13.1 的激活剂;K 2P18.1 的抑制剂;K 2P2.1 的激活剂;K 2P3.1 的通道阻断剂;K 2P4.1 的激活剂;K ir2.3 的激活剂;K ir3.4 的激活剂;K v4.2 的通道阻断剂;蛋白激酶 C zeta 的激活剂;TRPC6 的激活剂;TRPM2 的激活剂;TRPV4 的激活剂 |
| 产品介绍 |
是人体中最重要的一种多不饱和脂肪酸（PUFA），是人体“必需脂肪酸”之一，属n-6系列，简记为20:4( n-6)。它是人体内含量最丰富，最为活跃和最必需的一种多不饱和脂肪酸(PUFA)。它广泛存在于人类的脑细胞和神经末梢。人类大脑的60%是由脑结构脂构成，而AA就约占脑结构总量的40%-50%，在神经末梢甚至高达 70％。在正常人的血浆中的含量也高达400mg/L。母乳中也存在着丰富的AA，授乳第一周后母乳中AA的含量约占类脂物总量的0.4％，是母乳中含量最高的一种多不饱和脂肪酸。 |
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
| 活性类型 | Relation | Activity value | Units | Action Type | 期刊 | PubMed Id | doi | Assay Aladdin ID |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 208-033-4 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid |
| INCHI | 1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- |
| InChi Key | YZXBAPSDXZZRGB-DOFZRALJSA-N |
| Smiles | CCCCCC=CCC=CCC=CCC=CCCCC(=O)O |
| Isomeric SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O |
| 分子量 | 304.47 |
| Beilstein号 | 1713889 |
| Reaxy-Rn | 1713889 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1713889&ln= |
| 敏感性 | 空气及湿度和光敏感 |
|---|---|
| 折光率 | 1.4872 |
| 闪点(℉) | 113 °C |
| 闪点(℃) | 113°C |
| 沸点 | 169-171 °C/0.15 mmHg |
| 熔点 | -49°C |
| 分子量 | 304.500 g/mol |
| XLogP3 | 6.300 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 2 |
| 可旋转键计数Rotatable Bond Count | 14 |
| 精确质量Exact Mass | 304.24 Da |
| 单同位素质量Monoisotopic Mass | 304.24 Da |
| 拓扑极表面积Topological Polar Surface Area | 37.300 Ų |
| 重原子数Heavy Atom Count | 22 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 362.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 4 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 4 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H302: 吞食有害 H312: 皮肤接触有害 H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H332: 吸入有害 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P317: 如果被吞咽：请寻求医疗帮助。 P317: 寻求紧急医疗救助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| Merck Index | 765 |
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