| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| A423654-1ml |
1ml |
现货  |
|
| 别名 | 3-氨基-1-丙磺酸 | 高牛磺酸 | 3-氨基丙烷-1-磺酸 | 3-氨基丙烷磺酸 |
|---|---|
| 英文别名 | Acamprosate impurity A | KBio1_000348 | TRAMIPROSATE [MI] | 3-ammoniopropane-1-sulfonate | EINECS 222-977-4 | SCHEMBL26759 | 3-Amino-1-propanesulfonic acid | UNII-5K8EAX0G53 | 5K8EAX0G53 | GS-3103 | MLS000028639 | 1-Propanesulfonic acid, 3-amino- | AI3-52 |
| 规格或纯度 | 10mM in Water |
| 英文名称 | 3-Amino-1-propanesulfonic acid |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 作用类型 | 稳定剂 |
| 作用机制 | β 淀粉样蛋白 A4 蛋白稳定剂 |
| 产品介绍 |
重要的 GABA-mimetic 药物成分，可引起类似于 γ-氨基丁酸 (GABA) 诱导的神经反应。 Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA). |
| ALogP | -3.8 |
|---|
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 222-977-4 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | 3-aminopropane-1-sulfonic acid |
| INCHI | 1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7) |
| InChi Key | SNKZJIOFVMKAOJ-UHFFFAOYSA-N |
| Smiles | C(CN)CS(=O)(=O)O |
| Isomeric SMILES | C(CN)CS(=O)(=O)O |
| 分子量 | 139.17 |
| Reaxy-Rn | 1753803 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1753803&ln= |
| 熔点 | 293°C |
|---|---|
| 分子量 | 139.180 g/mol |
| XLogP3 | -3.800 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 4 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 139.03 Da |
| 单同位素质量Monoisotopic Mass | 139.03 Da |
| 拓扑极表面积Topological Polar Surface Area | 88.800 Ų |
| 重原子数Heavy Atom Count | 8 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 133.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS07 |
|---|---|
| 信号词 | 警告 |
| 危险声明 |
H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 1 |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
| 1. Shaocheng Liu, Zhenyu Guo, Xianxin Wu, Xinfeng Liu, Zijian Huang, Liang Li, Jinwen Zhang, Huanping Zhou, Ling-Dong Sun, Chun-Hua Yan. (2022) Zwitterions Narrow Distribution of Perovskite Quantum Wells for Blue Light-Emitting Diodes with Efficiency Exceeding 15%. ADVANCED MATERIALS, 35 (3): (2208078). [PMID:36398427] [10.1002/adma.202208078] |
| 2. Mengyue Hu, Xu Peng, Shubin Shi, Chang Wan, Can Cheng, Ningning Lei, Xixun Yu. (2022) Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification. Journal of Materials Chemistry B, 10 (40): (8218-8234). [PMID:36173240] [10.1039/D2TB01704K] |
| 3. Zhan Hao, Song Zhao, Qinghua Li, Yi Wang, Jun Zhang, Zhi Wang, Jixiao Wang. (2021) Reverse osmosis membranes with sulfonate and phosphate groups having excellent anti- scaling and anti-fouling properties. DESALINATION, 509 (115076). [10.1016/j.desal.2021.115076] |
| 4. Yaojun Ju, Harapriya Chakravarty, Kin Yip Tam. (2020) An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer’s Disease. ACS Chemical Neuroscience, 11 (20): (3346–3357). [PMID:33001625] [10.1021/acschemneuro.0c00464] |
| 5. Zhiqiang Man, Wenxiang Wu. (2024) Study on the Synthesis, Surface Activity, and Self-Assembly Behavior of Anionic Non-Ionic Gemini Surfactants. MOLECULES, 29 (8): (1725). [PMID:38675545] [10.3390/molecules29081725] |
| 6. Yuying Chen, Huimin Wu, Fei Jin, Hong-Liang Ge, Feng Gao, Qiong Wu, Song Wang, Ying Wang, Hua Yang. (2024) Sulfonate-modified fullerenes mimicking tentacle structures for humidity sensors. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 661 (977). [PMID:38330669] [10.1016/j.jcis.2024.02.024] |
| 7. He Junqiu, Sun Shan, Wang Hongfeng, Ying Zheng, Tam Kin Yip. (2025) Triple-Target Inhibition of Cholinesterase, Amyloid Aggregation, and GSK3β to Ameliorate Cognitive Deficits and Neuropathology in the Triple-Transgenic Mouse Model of Alzheimer’s Disease. Neuroscience Bulletin, (1-16). [PMID:39907971] [10.1007/s12264-025-01354-y] |
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