基本描述

英文别名	AI3-52371 \| HY-W010277 \| (3-Amino-propionylamino)-acetic acid \| N-L-Alanylglycine \| n-l-alanyl-Glycine \| NSC-89597 \| 2-[(2S)-2-aminopropanamido]acetic acid \| ((S)-2-Amino-propionylamino)-acetic acid \| L-Ala-Gly \| A866982 \| AS-55965 \| EINECS 208-083-7 \| L-
规格或纯度	≥99%
英文名称	Ala-Gly
生化机理	丙氨酰二肽，可用于如ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr 和 ala-phe的理化研究或评估二肽的分离技术。丙氨酰二肽也可用于研究细胞摄取机制，二肽的代谢或细胞生长补充。 L-丙氨酰甘氨酸是一种简单的营养的二肽，也可用于物理化学研究，如氢键和重金属的络合。
储存温度	-20°C储存
运输条件	超低温冰袋运输
纯度	≥99%

关联靶点（人）

ACE Tclin Angiotensin-converting enzyme (1423 活性数据)

点击查看靶蛋白信息： ACE

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 活性数据)

点击查看靶蛋白信息： SLC15A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SLC15A2 Tchem Solute carrier family 15 member 2 (186 活性数据)

点击查看靶蛋白信息： SLC15A2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

GAP1 General amino-acid permease GAP1 (481 活性数据)

点击查看靶蛋白信息： GAP1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	488195960
EC号	211-699-9
分子类型	小分子
IIUPAC Name	2-[[(2S)-2-aminopropanoyl]amino]acetic acid
INCHI	1S/C5H10N2O3/c1-3(6)5(10)7-2-4(8)9/h3H,2,6H2,1H3,(H,7,10)(H,8,9)/t3-/m0/s1
InChi Key	CXISPYVYMQWFLE-VKHMYHEASA-N
Smiles	CC(C(=O)NCC(=O)O)N
Isomeric SMILES	C[C@@H](C(=O)NCC(=O)O)N
分子量	146.14
Beilstein号	1723438
Reaxy-Rn	1723437
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723437&ln=

化学和物理性质

熔点	249-255°C
分子量	146.140 g/mol
XLogP3	-3.700
氢键供体数Hydrogen Bond Donor Count	3
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	3
精确质量Exact Mass	146.069 Da
单同位素质量Monoisotopic Mass	146.069 Da
拓扑极表面积Topological Polar Surface Area	92.400 Å²
重原子数Heavy Atom Count	10
形式电荷Formal Charge	0
复杂度Complexity	146.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	1
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07
信号词	警告
危险声明	H302: 吞食有害 H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
WGK Germany	3

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到6个结果

批号(Lot Number)	证书类型	货号
I2506049	分析证书	A121374
L2116125	分析证书	A121374
L2116128	分析证书	A121374
L1326001	分析证书	A121374
C2301534	分析证书	A121374
H1412058	分析证书	A121374

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Biegel A, Gebauer S, Hartrodt B, Brandsch M, Neubert K, Thondorf I. (2005) Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.. J Med Chem, 48 (13): (4410-9). [PMID:15974593]
2. E K Patterson. (1989-05-15) Inhibition by bestatin of a mouse ascites tumor dipeptidase. Reversal by certain substrates.. The Journal of biological chemistry, 264 ((14)): (8004-8011). [PMID:2722773]
3. L A Nafie,T B Freedman. (1993-01-01) Raman optical activity.. Methods in enzymology, 226 (470-482). [PMID:8277877]
4. C J Gray,N I Desai,R Gorst,G Masih. (1996-01-01) Synthesis of azaalanine peptides using the solid phase method.. Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity, 2 ((1)): (13-18). [PMID:9346831]
5. W W Navarre,H Ton-That,K F Faull,O Schneewind. (1999-05-21) Multiple enzymatic activities of the murein hydrolase from staphylococcal phage phi11. Identification of a D-alanyl-glycine endopeptidase activity.. The Journal of biological chemistry, 274 ((22)): (15847-15856). [PMID:10336488]
6. Y Wei,D K Lee,A Ramamoorthy. (2001-06-21) Solid-state (13)C NMR chemical shift anisotropy tensors of polypeptides.. Journal of the American Chemical Society, 123 ((25)): (6118-6126). [PMID:11414846]
7. Motoya Kohtani,Gary A Breaux,Martin F Jarrold. (2004-01-30) Water molecule adsorption on protonated dipeptides.. Journal of the American Chemical Society, 126 ((4)): (1206-1213). [PMID:14746492]
8. Trang U Vo,Linda B McGown. (2004-06-03) Selectivity of quadruplex DNA stationary phases toward amino acids in homodipeptides and alanyl dipeptides.. Electrophoresis, 25 ((9)): (1230-1236). [PMID:15174042]
9. Yousuke Tsuneyoshi,Shozo Tomonaga,Mari Asechi,Koji Morishita,D Michael Denbow,Mitsuhiro Furuse. (2007-06-01) Central administration of dipeptides, beta-alanyl-BCAAs, induces hyperactivity in chicks.. BMC neuroscience, 8 (37-37). [PMID:17537271]
10. L Padmaja,C Ravikumar,C James,V S Jayakumar,I Hubert Joe. (2008-02-05) Analysis of vibrational spectra of L-alanylglycine based on density functional theory calculations.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71 ((1)): (252-262). [PMID:18243781]
11. M Tafazzoli,S K Amini. (2008-02-15) Theoretical 13C chemical shift, 14N, and 2H quadrupole coupling- constant studies of hydrogen bonding in L-alanylglycine dipeptide.. Magnetic resonance in chemistry : MRC, 46 ((4)): (370-376). [PMID:18273875]
12. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912]
13. Puneet Ahuja,Riddhiman Sarkar,Paul R Vasos,Geoffrey Bodenhausen. (2009-05-16) Diffusion coefficients of biomolecules using long-lived spin states.. Journal of the American Chemical Society, 131 ((22)): (7498-7499). [PMID:19441812]
14. P R Vasos,A Comment,R Sarkar,P Ahuja,S Jannin,J-P Ansermet,J A Konter,P Hautle,B van den Brandt,G Bodenhausen. (2009-10-21) Long-lived states to sustain hyperpolarized magnetization.. Proceedings of the National Academy of Sciences of the United States of America, 106 ((44)): (18469-18473). [PMID:19841270]
15. Marie-Pierre Gaigeot. (2010-06-12) Infrared spectroscopy of the alanine dipeptide analog in liquid water with DFT-MD. Direct evidence for P(II)/beta conformations.. Physical chemistry chemical physics : PCCP, 12 ((35)): (10198-10209). [PMID:20539891]
16. Aurélien Bornet,Riddhiman Sarkar,Geoffrey Bodenhausen. (2010-07-10) Life-times of long-lived coherences under different motional regimes.. Journal of magnetic resonance (San Diego, Calif. : 1997), 206 ((1)): (154-156). [PMID:20615732]
17. Víctor Cruz, Javier Ramos, Javier Martínez-Salazar,. (2011-04-08) Water-mediated conformations of the alanine dipeptide as revealed by distributed umbrella sampling simulations, quantum mechanics based calculations, and experimental data.. The journal of physical chemistry. B, 115 ((16)): ( 4880-4886 ). [PMID:21469661]
18. Voislav Blagojevic,Alexander Chramow,Bradley B Schneider,Thomas R Covey,Diethard K Bohme. (2011-04-21) Differential mobility spectrometry of isomeric protonated dipeptides: modifier and field effects on ion mobility and stability.. Analytical chemistry, 83 ((9)): (3470-3476). [PMID:21504141]
19. Zhanli Wang,Saisai Zhang,Hongwei Jin,Wei Wang,Jianxin Huo,Lishe Zhou,Yongfu Wang,Fengqin Feng,Liangren Zhang. (2011-05-31) Angiotensin-I-converting enzyme inhibitory peptides: Chemical feature based pharmacophore generation.. European journal of medicinal chemistry, 46 ((8)): (3428-3433). [PMID:21621881]
20. Alessandro Pedretti,Laura De Luca,Cristina Marconi,Luca Regazzoni,Giancarlo Aldini,Giulio Vistoli. (2011-07-12) Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.. Bioorganic & medicinal chemistry, 19 ((15)): (4544-4551). [PMID:21741846]
21. W M Zuk,T B Freedman,L A Nafie. (1989-11-01) Vibrational CD studies of the solution conformation of simple alanyl peptides as a function of pH.. Biopolymers, 28 ((11)): (2025-2044). [PMID:2597744]
22. C L Welch,B J Campbell. (1980-01-01) Uptake of glycine from L-alanylglycine into renal brush border vesicles.. The Journal of membrane biology, 54 ((1)): (39-50). [PMID:7205942]
23. E N Zvonkova,E I Khabarova,I A Vasilenko,R P Evstigneeva. (1981-01-01) [Interaction of poly-DL-alanylglycine with a phospholipid membrane].. Doklady Akademii nauk SSSR, 259 ((3)): (726-727). [PMID:7285782]
24. C Schiene-Fischer,G Fischer. (2001-06-28) Direct measurement indicates a slow cis/trans isomerization at the secondary amide peptide bond of glycylglycine.. Journal of the American Chemical Society, 123 ((26)): (6227-6231). [PMID:11427045]
25. Lee Ayres,P Hans H M Adams,Dennis W P M Löwik,Jan C M van Hest. (2005-03-15) Beta-sheet side chain polymers synthesized by atom-transfer radical polymerization.. Biomacromolecules, 6 ((2)): (825-831). [PMID:15762647]
26. Yan Cheng,Min Bai,Xinmei Wang,Yongfei Ming,Jinmao You. (2006-07-13) [Chiral separation of dipeptides by capillary electrophoresis].. Se pu = Chinese journal of chromatography, 24 ((2)): (188-191). [PMID:16830473]
27. Masatoshi Watabe,Hiroto Fukuda,Koichiro Kitsukawa,Hiroshi Nakajima,Yasuhiko Yukawa,Satoshi Igarashi,Yuki Fujii,Toshio Takayama. (2006-07-22) Preparation of platinum(IV) complexes with dipeptide and diimine. X-ray crystal structure and 195Pt NMR spectra.. Journal of inorganic biochemistry, 100 ((10)): (1653-1659). [PMID:16857262]
28. Gregory A Barding,Takeshi Fukao,Szabolcs Béni,Julia Bailey-Serres,Cynthia K Larive. (2011-10-25) Differential metabolic regulation governed by the rice SUB1A gene during submergence stress and identification of alanylglycine by 1H NMR spectroscopy.. Journal of proteome research, 11 ((1)): (320-330). [PMID:22017194]
29. Molly Moravek,Senait Fisseha,Jason E Swain. (2012-01-17) Dipeptide forms of glycine support mouse preimplantation embryo development in vitro and provide protection against high media osmolality.. Journal of assisted reproduction and genetics, 29 ((3)): (283-290). [PMID:22246224]
30. Gregory A Barding,Szabolcs Béni,Takeshi Fukao,Julia Bailey-Serres,Cynthia K Larive. (2012-12-05) Comparison of GC-MS and NMR for metabolite profiling of rice subjected to submergence stress.. Journal of proteome research, 12 ((2)): (898-909). [PMID:23205590]
31. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang. (2017) Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency. JOURNAL OF CHROMATOGRAPHY A, 1509 (83). [PMID:28629939] [10.1016/j.chroma.2017.06.034]
32. Wei Wang, Lihong Ma, Ping Lin, Kaixuan Xu. (2016) Separation and detection of amino acid metabolites of Escherichia coli in microbial fuel cell with CE. ELECTROPHORESIS, 37 (14): (2106-2111). [PMID:27121957] [10.1002/elps.201600007]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

=

浓度

x

体积

x

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

x

体积 1 (V1)

=

浓度 2 (C2)

x

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

=

质量（小瓶）

÷

所需的复溶浓度

货号 (SKU)	包装规格	是否现货
A121374-200mg	200mg	现货
A121374-1g	1g	现货
A121374-5g	5g	现货

L-丙氨酰甘氨酸

库存信息

库存信息

库存信息

基本描述

关联靶点（人）

关联靶点（其它种属）

作用机制

名称和识别符

化学和物理性质

安全和危险性（GHS）

质检证书（CoA,COO,BSE/TSE 和分析图谱)

此产品的引用文献

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器