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氨基吡嗪

8篇引用文献 COA COA
    级别和纯度:
  • ≥99%
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货号 (SKU) 包装规格 是否现货 价格 数量
A111242-1g
 1g 现货 Stock Image
A111242-5g
 5g 现货 Stock Image
A111242-10g
 10g 现货 Stock Image
A111242-25g
 25g 现货 Stock Image
A111242-50g
 50g 现货 Stock Image
A111242-100g
 100g 现货 Stock Image
A111242-500g
 500g 期货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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六元杂环化合物 (1701) 吡嗪类 (193)
main product photo

基本描述

别名 2-氨基吡嗪 | 2-氨基哌嗪
英文别名 F2169-0758 | Pyrazine, 2-amino- | EINECS 225-748-7 | AC-907/25014024 | AKOS000120229 | MFCD00007083 | pyrazineamine | FT-0682702 | 2-(1,3-dioxoisoindolin-2-yl)ethyl acetate | STL137799 | CL4536 | Aminopyrazine, purum, >=97.0% (NT) | DTXSID80198510 | W-105
规格或纯度 ≥99%
英文名称 Aminopyrazine
运输条件 常规运输
产品介绍

Aminopyrazine is a synthetic intermediate.A synthetic intermediate

Aminopyrazine is a synthetic intermediate.
A synthetic intermediate
纯度 ≥99%

关联靶点（人）

HSP90AA1 Tchem Heat shock protein HSP 90-alpha (4115 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488185616
EC号 225-748-7
分子类型 小分子
IIUPAC Name pyrazin-2-amine
INCHI 1S/C4H5N3/c5-4-3-6-1-2-7-4/h1-3H,(H2,5,7)
InChi Key XFTQRUTUGRCSGO-UHFFFAOYSA-N
Smiles C1=CN=C(C=N1)N
Isomeric SMILES C1=CN=C(C=N1)N
分子量 95.1
Beilstein号 107025
Reaxy-Rn 107025
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=107025&ln=

化学和物理性质

溶解性 Soluble in water.
密度 1.216
熔点 117-120°C
分子量 95.100 g/mol
XLogP3 -0.100
氢键供体数Hydrogen Bond Donor Count 1
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 0
精确质量Exact Mass 95.0483 Da
单同位素质量Monoisotopic Mass 95.0483 Da
拓扑极表面积Topological Polar Surface Area 51.800 Ų
重原子数Heavy Atom Count 7
形式电荷Formal Charge 0
复杂度Complexity 54.900
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS07
信号词 警告
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激
预防措施声明

P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾

P264: 处理后要彻底洗手。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。

P319: 如果你感到不适，请寻求医疗帮助。
WGK Germany 3
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到23个结果

批号(Lot Number) 证书类型 货号
L2114074 分析证书 A111242
L2114077 分析证书 A111242
L2114078 分析证书 A111242
L2114131 分析证书 A111242
G2102074 分析证书 A111242
B2325265 分析证书 A111242
A2329023 分析证书 A111242
C2514194 分析证书 A111242
L2210008 分析证书 A111242
L2210009 分析证书 A111242
L2210010 分析证书 A111242
L2210011 分析证书 A111242
L2210012 分析证书 A111242
L2210013 分析证书 A111242
L2210014 分析证书 A111242
L2210015 分析证书 A111242
L2210016 分析证书 A111242
B2505097 分析证书 A111242
K1419045 分析证书 A111242
H1815017 分析证书 A111242
C2224034 分析证书 A111242
B2314170 分析证书 A111242
I2318175 分析证书 A111242

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此产品的引用文献

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引用文献

1. J F Cavalier,M Burton,F Dussart,C Marchand,J F Rees,J Marchand-Brynaert.  (2001-05-17)  Catechol derivatives of aminopyrazine and cell protection against UVB-induced mortality..  Bioorganic & medicinal chemistry,  9  ((4)): (1037-1044).  [PMID:11354660]
2. Abdullah M Asiri,Khadija O Badahdah.  (2007-10-26)  Synthesis of some new anils: part 1. Reaction of 2-hydroxy-benzaldehyde and 2-hydroxynaphthaldehyde with 2-aminopyridene and 2-aminopyrazine..  Molecules (Basel, Switzerland),  12  ((8)): (1796-1804).  [PMID:17960088]
3. Anna Eriksson,Martin Höglund,Elin Lindhagen,Anna Aleskog,Sadia Bashir Hassan,Carina Ekholm,Karin Fhölenhag,Annika Jenmalm Jensen,Agneta Löthgren,Martin Scobie,Rolf Larsson,Vendela Parrow.  (2010-08-14)  Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemia..  Biochemical pharmacology,  80  ((10)): (1507-1516).  [PMID:20705060]
4. Takaaki Miura,Takaaki A Fukami,Kiyoshi Hasegawa,Naomi Ono,Atsushi Suda,Hidetoshi Shindo,Dong-Oh Yoon,Sung-Jin Kim,Young-Jun Na,Yuko Aoki,Nobuo Shimma,Takuo Tsukuda,Yasuhiko Shiratori.  (2011-08-31)  Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design..  Bioorganic & medicinal chemistry letters,  21  ((19)): (5778-5783).  [PMID:21875802]
5. Suman K Vodnala,Thomas Lundbäck,Birger Sjöberg,Richard Svensson,Martin E Rottenberg,Lars G J Hammarström.  (2012-12-21)  In vitro and in vivo activities of 2-aminopyrazines and 2-aminopyridines in experimental models of human African trypanosomiasis..  Antimicrobial agents and chemotherapy,  57  ((2)): (1012-1018).  [PMID:23254423]
6. Robert Jirásko,Michal Holčapek,Martin Kuneš,Aleš Svatoš.  (2014-05-21)  Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging..  Analytical and bioanalytical chemistry,  406  ((19)): (4601-4610).  [PMID:24842405]
7. W H Lunn,J K Shadle.  (1992-11-01)  Mercapturic acid formation from 2-aminopyrazine in rats..  Xenobiotica; the fate of foreign compounds in biological systems,  22  ((11)): (1239-1241).  [PMID:1492416]
8. Frédéric De Wael,Giulio G Muccioli,Didier M Lambert,Thérèse Sergent,Yves-Jacques Schneider,Jean-François Rees,Jacqueline Marchand-Brynaert.  (2010-06-24)  Chemistry around imidazopyrazine and ibuprofen: discovery of novel fatty acid amide hydrolase (FAAH) inhibitors..  European journal of medicinal chemistry,  45  ((9)): (3564-3574).  [PMID:20570023]
9. Boyu Cai, Qing Jiang, Wendi Xu, Luze Wang, Zhonglin Luo, Biaobing Wang.  (2023)  A nitrogen-rich DOPO-based phosphoramide for improving the fire resistance of polycarbonate with comparable mechanical property.  JOURNAL OF APPLIED POLYMER SCIENCE,  140  (41): (e54513).  [10.1002/app.54513]
10. Huahao Wang, Yaping Ding, Mengjia Ning, Miao Yu, Wenji Zheng, Xuehua Ruan, Yuan Xi, Yan Dai, Hongjing Liu, Gaohong He.  (2023)  Amino-functional CPL-1 with abundant CO2-philic groups to enhance MMM-based CO2 separation.  SEPARATION AND PURIFICATION TECHNOLOGY,  322  (124227).  [10.1016/j.seppur.2023.124227]
11. Lei Wang, Xianying Bai, Yawei Gu, Xinxin Shi, Shilong Wang, Jingxian Hua, Rujing Hou, Chongqing Wang, Yichang Pan.  (2023)  Aligned Metal–Organic Framework Nanoplates in Mixed-Matrix Membranes for Highly Selective CO2/CH4 Separation.  Advanced Materials Interfaces,  10  (12): (2202524).  [10.1002/admi.202202524]
12. Hao Tang, Hong Zhou.  (2019)  A novel nitrogen, phosphorus, and boron ionic pair compound toward fire safety and mechanical enhancement effect for epoxy resin.  POLYMERS FOR ADVANCED TECHNOLOGIES,  31  (4): (885-897).  [10.1002/pat.4823]
13. Hao Tang, ZongMin Zhu, Rui Chen, JunJie Wang, Hong Zhou.  (2019)  Synthesis of DOPO-based pyrazine derivative and its effect on flame retardancy and thermal stability of epoxy resin.  POLYMERS FOR ADVANCED TECHNOLOGIES,  30  (9): (2331-2339).  [10.1002/pat.4674]
14. Huan Yang, Li He, Shuang Pan, Hui Liu, Xiaoli Hu.  (2019)  Nitrogen-doped fluorescent carbon dots for highly sensitive and selective detection of tannic acid.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  210  (111).  [PMID:30453186] [10.1016/j.saa.2018.11.029]
15. Hongmei Chen, Yanyun Fan, Kexin Shi, Peng Wang, Chong-Chen Wang.  (2024)  Implanting pyrazine ring into g-C3N4 for accelerating photocatalytic hydrogen evolution.  JOURNAL OF ALLOYS AND COMPOUNDS,  976  (173410).  [10.1016/j.jallcom.2023.173410]
16. Qi Yang, Zhao Wang, Li Yang, Yue Zhu, Han Cao, Yao Wu.  (2025)  Simple fabrication of bimetallic metal-organic framework derived magnetic flower-like composites for selective adsorption of hemoglobin: isotherm, kinetic, and thermodynamic studies.  Materials Research Express,  [10.1088/2053-1591/adbdad]

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