茜素

含钙组织的红色斑点

24篇引用文献

COA

级别和纯度:

≥97%

CAS编号: 72-48-0
分子式: C₁₄H₈O₄
分子量: 240.21
Beilstein号: 1914037
EC号: 200-782-5
MDL号: MFCD00001201
PubChem编号: 6293
PubChem SID: 504751056

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货号 (SKU)	包装规格	是否现货
A110681-5g	5g	现货
A110681-25g	25g	现货
A110681-100g	100g	现货
A110681-500g	500g	现货

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Fluorescent Dye (370) 六元碳环化合物 (251) 蒽醌类 (58)

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基本描述

别名	1,2-二羟基蒽醌 \| 媒染红11 \| 颜料红83
英文别名	Mitsui Alizarine BS \| Mordant Red 11 \| NSC7212 \| NSC-7212 \| 9, 1,2-dihydroxy- \| ALIZARINE \| Alizarine Lake Red 3P \| KBio2_003434 \| 2,9-dihydroxy-1,10-anthraquinone \| D&C ORANGE NO. 15 (DELISTED) \| KBio2_006002 \| KBioGR_002050 \| Pincoffin \| Sanyo Carmine l
规格或纯度	≥97%
英文名称	Alizarin
生化机理	茜素（1，2-二羟基蒽醌）是一种蒽醌染料，是茜草染料的主要发色体。它被用作生产湖泊颜料的染料。茜素是茜草科、大戟科、五倍子科、老鹳草科植物根提取物的主要成分。可检测滑液中的钙化合物。确定成骨分化。在体内与游离离子钙形成沉淀。
应用	酸碱指示剂(0.5%溶液)，pH变色范围5.5(黄色)-6.8(红色)。作铝、铟、汞、锌和锆的点滴试剂。神经组织和原生动物活体染色剂。
储存温度	2-8°C储存,干燥
运输条件	冰袋运输
备注	如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍	微溶于水，溶于丙酮、甲醇、乙醇(沸腾下)、碱和溶纤素，微溶于苯、四氯化碳、甲苯、二甲苯、吡啶、二硫化碳和冰乙酸，不溶于乙醇(冷)、斯淘特溶剂，溶于碱液呈蓝紫色，遇浓硫酸呈黄光红色，稀释后产生红光黄色沉淀，遇氢氧化钠为紫色。110℃升华(0.27kPa)。半数致死量(小鼠，腹腔)500mg/k 酸碱指示剂(0.5%溶液)，pH变色范围5.5(黄色)-6.8(红色)。作铝、铟、汞、锌和锆的点滴试剂。神经组织和原生动物活体染色剂。
纯度	≥97%

关联靶点（人）

CYP1B1 Tchem 细胞色素 P450 1B1(Cytochrome P450 1B1) (1 活性数据)

点击查看靶蛋白信息： CYP1B1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 活性数据)

点击查看靶蛋白信息： MAOA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 活性数据)

点击查看靶蛋白信息： MAOB

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP1B1 Tchem Cytochrome P450 1B1 (1148 活性数据)

点击查看靶蛋白信息： CYP1B1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 活性数据)

点击查看靶蛋白信息： PLK1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 活性数据)

点击查看靶蛋白信息： ALOX15B

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 活性数据)

点击查看靶蛋白信息： ALDH1A1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 活性数据)

点击查看靶蛋白信息： ALOX12

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 活性数据)

点击查看靶蛋白信息： ALOX15

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 活性数据)

点击查看靶蛋白信息： UGT1A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 活性数据)

点击查看靶蛋白信息： PIN1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)

点击查看靶蛋白信息： CYP3A4

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

A498 (42825 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ACHN (49357 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CAKI-1 (44928 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

CCRF-CEM (65223 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

COLO 205 (50209 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

DLD-1 (17511 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

DMS-273 (14108 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HT-29 (80576 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

K562 (73714 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

KM12 (47707 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

M14 (47487 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

MOLT-4 (49676 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

OVCAR-3 (48710 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

OVCAR-4 (44535 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

OVCAR-5 (45555 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

OVCAR-8 (47708 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Raji (5516 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RPMI-8226 (44974 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

RXF 393 (41971 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SF-295 (48000 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SK-MEL-2 (46422 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SK-MEL-28 (48833 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SN12C (47755 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SNB-19 (46794 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SNB-78 (14240 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

TK-10 (45540 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

U-251 (51189 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

UACC-257 (46019 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

UACC-62 (47335 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

UO-31 (46270 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

XF498 (12972 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

786-0 (47912 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

A549 (127892 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

EKVX (44102 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NCI-H1299 (3248 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

NCI-H322M (45589 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HCC 2998 (41480 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HCT-116 (91556 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

HOP-92 (41141 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

关联靶点（其它种属）

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 活性数据)

点击查看靶蛋白信息： pol

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Ttr Transthyretin (14 活性数据)

点击查看靶蛋白信息： Ttr

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 活性数据)

点击查看靶蛋白信息： Mapk1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Pklr Pyruvate kinase isozymes R/L (113 活性数据)

点击查看靶蛋白信息： Pklr

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Brugia malayi (1377 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

P388 (20296 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

L929 (3802 活性数据)

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活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 活性数据)

点击查看靶蛋白信息： GCN5

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A (1629 活性数据)

点击查看靶蛋白信息： Dyrk1a

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

gag-pol Gag-Pol polyprotein (8 活性数据)

点击查看靶蛋白信息： gag-pol

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Erwinia amylovora (182 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

rmtA RmtA (95 活性数据)

点击查看靶蛋白信息： rmtA

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 活性数据)

点击查看靶蛋白信息： Mapt

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Impa1 Inositol monophosphatase 1 (16203 活性数据)

点击查看靶蛋白信息： Impa1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

Phosphoglycerate kinase, glycosomal (2184 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

ESR1 Estrogen receptor (4 活性数据)

点击查看靶蛋白信息： ESR1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 活性数据)

点击查看靶蛋白信息： vpr

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 活性数据)

点击查看此靶标相关信息

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

PubChem SID	504751056
EC号	200-782-5
分子类型	小分子
IIUPAC Name	1,2-dihydroxyanthracene-9,10-dione
INCHI	1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H
InChi Key	RGCKGOZRHPZPFP-UHFFFAOYSA-N
Smiles	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
Isomeric SMILES	C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
分子量	240.21
Beilstein号	1914037
Reaxy-Rn	1914037
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1914037&ln=

化学和物理性质

溶解性	DMSO (Slightly), Methanol (Slightly)
密度	1.54
沸点	430°C
熔点	290°C
分子量	240.210 g/mol
XLogP3	3.200
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	0
精确质量Exact Mass	240.042 Da
单同位素质量Monoisotopic Mass	240.042 Da
拓扑极表面积Topological Polar Surface Area	74.600 Å²
重原子数Heavy Atom Count	18
形式电荷Formal Charge	0
复杂度Complexity	378.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	0
定义的键立体中心计数Defined Bond Stereocenter Count	0
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	0
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

象形图	GHS07, GHS08
信号词	警告
危险声明	H341: 怀疑引起遗传缺陷 H315+H320: 引起皮肤和眼睛刺激
预防措施声明	P201: 使用前获取特殊说明 P202: 在阅读并理解所有安全预防措施之前，不要进行操作。 P264: 处理后要彻底洗手。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P302+P352: 如皮肤沾染：用水充分清洗。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P308+P313: 如接触到或有疑虑：求医/就诊。 P332+P313: 如发生皮肤刺激：求医/就诊。 P337+P313: 如仍觉眼刺激：求医/就诊。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P501: 将内容物/容器处理到。。。
WGK Germany	3
RTECS	CB6580000
Merck Index	251
个人防护装备	Eyeshields,Faceshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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找到12个结果

批号(Lot Number)	证书类型	货号
F2102091	分析证书	A110681
F2510219	分析证书	A110681
H2302033	分析证书	A110681
H2302034	分析证书	A110681
H2302036	分析证书	A110681
F2519785	分析证书	A110681
H1905186	分析证书	A110681
B2325283	分析证书	A110681
B2325284	分析证书	A110681
B2325285	分析证书	A110681
J2214255	分析证书	A110681
J2214254	分析证书	A110681

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引用文献

1. Jin-jing Hu, Zeng-hui Sun, Zi-wei Wu, Chao Tu, Li Cui, Yao-jun Tan. (2024) One-Step Preparation of Ph-Sensitive and Antibacterial Calcium Alginate Fibers: In Situ Reduction Method and Original Solution Dyeing. MACROMOLECULAR CHEMISTRY AND PHYSICS, 225 (4): (2300255). [10.1002/macp.202300255]
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