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氨苄青霉素钠

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货号 (SKU) 包装规格 是否现货 价格 数量
A105484-5g
5g 现货 Stock Image
A105484-25g
25g 现货 Stock Image
A105484-100g
100g 现货 Stock Image
A105484-500g
500g 现货 Stock Image

基本描述

别名 氨苄西林钠 | 氨苄西林 钠盐 | 氨苄青霉素 钠盐 | 阿苄西林钠 | 胺苄青霉素钠 | 安比西林钠 | 氨必西林钠
英文别名 AMPICILLIN SODIUM (USP MONOGRAPH) | sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | A836527 | Ampicillin (as sodium) | AMPICILLIN SODIUM [GREEN BOOK] | D-(-)-alpha-Aminobenzylpe
规格或纯度 用于细胞培养
英文名称 Ampicillin Na
生化机理 β-内酰胺类抗生素,具有连接到青霉素结构上的氨基侧链。青霉素衍生物,通过灭活细菌细胞膜内表面上的转肽酶,抑制细菌细胞壁的合成(肽聚糖交联)。仅对生长的 Escherichia coli 具有杀菌作用。抗性方式:通过 β-内酰胺酶使氨苄西林的 β-内酰胺环分裂。抗菌谱:革兰氏阴性和革兰氏阳性细菌。
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized throμgh filtration and stored frozen, where it will be stable for months.半合成的青霉素,抗革兰氏阳性及阴性菌。 属β-内酰胺酶抗生素,氨基基团链连接到青霉素结构上。属青霉素衍生物,依靠在细菌细胞膜的内层面使转肽酶(transpeptidases)失活抑制细菌细胞壁的合成。

Ampicillin is reported as slightly soluble in water, practically insoluble in alcohol, chloroform, ether and fixed oils but soluble in dilute acids or bases. The solution should not be autoclaved; a stock solution should be sterilized through filtration and stored frozen, where it will be stable for months.
Used to select for ampicillin resistance in mutated and transformed cells.

关联靶点(人)

POLB Tchem DNA polymerase beta (23632 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
POLH Tchem DNA polymerase eta (21678 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点(其它种属)

ampC Beta-lactamase AmpC (62480 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cruzipain (33337 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ftsZ Cell division protein ftsZ (97 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Streptococcus pneumoniae (31063 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ralstonia solanacearum (520 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bacillus subtilis (32866 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bacillus cereus (7522 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CCT2 T-complex protein 1 subunit beta (5007 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504769486
分子类型 小分子
IIUPAC Name sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
INCHI 1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
InChi Key KLOHDWPABZXLGI-YWUHCJSESA-M
Smiles CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)[O-])C.[Na+]
Isomeric SMILES CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)[O-])C.[Na+]
分子量 371.39
Reaxy-Rn 1231014
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1231014&ln=

化学和物理性质

溶解性 H2O: soluble50 mg/mL
密度 0.945
熔点 215°C
分子量 371.400 g/mol
XLogP3
氢键供体数Hydrogen Bond Donor Count 2
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 4
精确质量Exact Mass 371.092 Da
单同位素质量Monoisotopic Mass 371.092 Da
拓扑极表面积Topological Polar Surface Area 141.000 Ų
重原子数Heavy Atom Count 25
形式电荷Formal Charge 0
复杂度Complexity 568.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 4
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 2

安全和危险性(GHS)

象形图 GHS08
信号词 Danger
个人防护装备 dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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批号(Lot Number) 证书类型 货号
C2511047 分析证书 A105484
C2511052 分析证书 A105484
C2511054 分析证书 A105484
C2511046 分析证书 A105484
J2409137 分析证书 A105484
J2409138 分析证书 A105484
E2414214 分析证书 A105484
E2414213 分析证书 A105484
A2404026 分析证书 A105484
A2404028 分析证书 A105484
A2404037 分析证书 A105484
A2404038 分析证书 A105484
A2404189 分析证书 A105484
A2404279 分析证书 A105484
A2305013 分析证书 A105484
A2305014 分析证书 A105484
A2305015 分析证书 A105484
A2305016 分析证书 A105484
A2305017 分析证书 A105484
A2305018 分析证书 A105484
A2305019 分析证书 A105484
C2224120 分析证书 A105484
C2224121 分析证书 A105484
C2224124 分析证书 A105484
C2224167 分析证书 A105484
K2229864 分析证书 A105484
L2214678 分析证书 A105484

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溶液计算器