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N-乙酰-D-氨基葡萄糖

    级别和纯度:
  • ≥98%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
A105211-25g
25g 现货 Stock Image
A105211-100g
100g 现货 Stock Image
A105211-500g
500g 现货 Stock Image
A105211-2.5kg
2.5kg 现货 Stock Image

基本描述

别名 N-乙酰氨基葡萄糖 | 2-乙酰氨基-2-脱氧-D-吡喃葡萄糖
英文别名 2-Acetamido-2-deoxy-D-glucopyranose | D-GlcNAc
规格或纯度 ≥98%
英文名称 N-Acetyl-D-glucosamine
储存温度 -20°C储存,充氩
运输条件 超低温冰袋运输
产品介绍

溶于水。 N-乙酰-D-氨基葡萄糖是生物细胞内许多重要多糖的基本组成单位,尤其是甲壳类动物的外骨骼含量最高。它是合成双歧因子的重要前体,在生物体内具有许多重要生理功能。

应用

N-乙酰-D-葡萄糖胺已用于:
1.用作凝集素组织化学竞争性抑制糖;
2.用作培养伯氏疏螺旋体螺旋体菌(Borrelia burgdorferi spirochetes)株的 Barbour-Stonner-Kelly (BSK) 培养基成分;
3.用作重悬肺炎链球菌(Streptococcus pneumoniae)菌株的结合缓冲液成分,以便通过抑制测定检验M-ficolin纤维胶凝蛋白与肺炎链球菌(S. pneumoniae )菌株结合的特异性;

N-Acetyl-D-glucosamine (D-GlcNAc) is a derivitized glucose monomer found in polymers of bacterial cell walls, chitin, hyaluronic acids and various glycans. D-GlcNAc is used to identify, differentiate and characterize N-acetyl-β-D-hexoaminidase(s).

纯度 ≥98%

关联靶点(其它种属)

Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 488191997
EC号 231-368-2
分子类型 小分子
Isomeric SMILES CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O
分子量 221.21
Beilstein号 1727589
Reaxy-Rn 1727589
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1727589&ln=

化学和物理性质

溶解性 Solubility in Water almost transparency
密度 1.5
敏感性 对湿度敏感
比旋光度 +39.0 to +43.0 deg(C=1, H2O)
熔点 211°C
分子量 221.210 g/mol
XLogP3 -3.400
氢键供体数Hydrogen Bond Donor Count 5
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 6
精确质量Exact Mass 221.09 Da
单同位素质量Monoisotopic Mass 221.09 Da
拓扑极表面积Topological Polar Surface Area 127.000 Ų
重原子数Heavy Atom Count 15
形式电荷Formal Charge 0
复杂度Complexity 221.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 4
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性(GHS)

WGK Germany 3
个人防护装备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

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G2523122 分析证书 A105211
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此产品的引用文献

引用文献

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